''Mandragora caulescens'', the Himalayan mandrake, is a

perennial A perennial plant or simply perennial is a plant that lives more than two years. The term ('' per-'' + '' -ennial'', "through the years") is often used to differentiate a plant from shorter-lived annuals and biennials. The term is also wide ...

herbaceous plant Herbaceous plants are vascular plants that have no persistent woody stems above ground. This broad category of plants includes many perennials, and nearly all annuals and biennials. Definitions of "herb" and "herbaceous" The fourth edition of t ...

in the family

Solanaceae The Solanaceae , or nightshades, are a family of flowering plants that ranges from annual and perennial herbs to vines, lianas, epiphytes, shrubs, and trees, and includes a number of agricultural crops, medicinal plants, spices, weeds, and orn ...

, native to the

Himalaya The Himalayas, or Himalaya (; ; ), is a mountain range in Asia, separating the plains of the Indian subcontinent from the Tibetan Plateau. The range has some of the planet's highest peaks, including the very highest, Mount Everest. Over 100 ...

s and mountainous regions of

Myanmar Myanmar, ; UK pronunciations: US pronunciations incl. . Note: Wikipedia's IPA conventions require indicating /r/ even in British English although only some British English speakers pronounce r at the end of syllables. As John C. Wells, Joh ...

and south-west

China China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and ...

. One of the differences from the other species of '' Mandragora'' is that it has a stem, whereas they are stemless. Like all species of ''Mandragora'', it contains

tropane alkaloid Tropane alkaloids are a class of bicyclic .2.1alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. Tropane alkaloids occur naturally in many members of the plant family Solanaceae. Certain tropane alkaloid ...

s, making it toxic. It is used in

traditional Chinese medicine Traditional Chinese medicine (TCM) is an alternative medical practice drawn from traditional medicine in China. It has been described as "fraught with pseudoscience", with the majority of its treatments having no logical mechanism of action ...

Description

''Mandragora caulescens'' is a

with a thick root. There is considerable variability in the size and shape of its parts and in the colour of its flowers. Unlike other members of the genus ''Mandragora'', it usually has a stem, long (sometimes up to ), making the plant as a whole usually tall. The leaves are mostly basal but are also found along the stem. They are up to long, including the stalk ( petiole). The flowering period is from April or May to July or September, with fruits appearing until October. The flowers are borne singly on stalks (

pedicels In botany, a pedicel is a stem that attaches a single flower to the inflorescence. Such inflorescences are described as ''pedicellate''. Description Pedicel refers to a structure connecting a single flower to its inflorescence. In the absenc ...

) long. The

sepal A sepal () is a part of the flower of angiosperms (flowering plants). Usually green, sepals typically function as protection for the flower in bud, and often as support for the petals when in bloom., p. 106 The term ''sepalum'' was coined b ...

s are joined at the base to form a lobed cup-shaped structure, often nearly as long as the

petal Petals are modified Leaf, leaves that surround the reproductive parts of flowers. They are often advertising coloration, brightly colored or unusually shaped to attract pollinators. All of the petals of a flower are collectively known as the ''c ...

s. The petals are dark purple or yellow, similarly joined at the base with lobes about half their length of . The

stamen The stamen (plural ''stamina'' or ''stamens'') is the pollen-producing reproductive organ of a flower. Collectively the stamens form the androecium., p. 10 Morphology and terminology A stamen typically consists of a stalk called the filame ...

s are joined to the base of the petals, and vary considerably in length, with the anthers long. The fruit is a

berry A berry is a small, pulpy, and often edible fruit. Typically, berries are juicy, rounded, brightly colored, sweet, sour or tart, and do not have a stone or pit, although many pips or seeds may be present. Common examples are strawberries, raspb ...

, greenish white to yellow in colour, up to across. The numerous seeds are yellow to light brown, long.

Taxonomy

''Mandragora caulescens'' was first described by

Charles Baron Clarke Charles Baron Clarke (17 June 1832 – 25 August 1906) was a British botanist. He was born at Andover, Hampshire, Andover, the eldest son of Turner Poulter Clarke. He was educated at King's College School, London, and at Trinity College, Cambrid ...

in 1883. In 1978, division into four subspecies was proposed, but this has not been accepted by subsequent researchers. ''Mandragora tibetica'', described in 1970, and ''Mandragora chinghaiensis'', described in 1978, are also, , not considered to be sufficiently differentiated from ''M. caulescens'', although the ''Flora of China'' says that "further study may lead to separation of independent taxa from the single species recognized here." A molecular phylogenetic study found that ''M. caulescens'' (including ''M. chinghaiensis'') is distinct from the remaining species within the genus, which form a separate

clade A clade (), also known as a monophyletic group or natural group, is a group of organisms that are monophyletic – that is, composed of a common ancestor and all its lineal descendants – on a phylogenetic tree. Rather than the English term, ...

Distribution and habitat

''Mandragora caulescens'' is a "Sino-Himalayan" species, native to

Nepal Nepal (; ne, नेपाल ), formerly the Federal Democratic Republic of Nepal ( ne, सङ्घीय लोकतान्त्रिक गणतन्त्र नेपाल ), is a landlocked country in South Asia. It is mai ...

, northern

India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the so ...

(including

Sikkim Sikkim (; ) is a state in Northeastern India. It borders the Tibet Autonomous Region of China in the north and northeast, Bhutan in the east, Province No. 1 of Nepal in the west and West Bengal in the south. Sikkim is also close to the Siligur ...

from where it was first described),

Bhutan Bhutan (; dz, འབྲུག་ཡུལ་, Druk Yul ), officially the Kingdom of Bhutan,), is a landlocked country in South Asia. It is situated in the Eastern Himalayas, between China in the north and India in the south. A mountainous ...

, and south-west

(south-east

Qinghai Qinghai (; alternately romanized as Tsinghai, Ch'inghai), also known as Kokonor, is a landlocked province in the northwest of the People's Republic of China. It is the fourth largest province of China by area and has the third smallest po ...

, west

Sichuan Sichuan (; zh, c=, labels=no, ; zh, p=Sìchuān; alternatively romanized as Szechuan or Szechwan; formerly also referred to as "West China" or "Western China" by Protestant missions) is a province in Southwest China occupying most of the ...

, east Xizang (Tibet), and north-west

Yunnan Yunnan , () is a landlocked Provinces of China, province in Southwest China, the southwest of the People's Republic of China. The province spans approximately and has a population of 48.3 million (as of 2018). The capital of the province is ...

). ''M. caulescens'' grows in open areas, such as grassland, moorland, pastures and stony slopes and screes, particularly among ''

Rhododendron ''Rhododendron'' (; from Ancient Greek ''rhódon'' "rose" and ''déndron'' "tree") is a very large genus of about 1,024 species of woody plants in the heath family (Ericaceae). They can be either evergreen or deciduous. Most species are nati ...

'' shrubs. It is found in the

subalpine Montane ecosystems are found on the slopes of mountains. The alpine climate in these regions strongly affects the ecosystem because temperatures fall as elevation increases, causing the ecosystem to stratify. This stratification is a crucial f ...

and

alpine zone Alpine tundra is a type of natural region or biome that does not contain trees because it is at high elevation, with an associated alpine climate, harsh climate. As the latitude of a location approaches the poles, the threshold elevation for alp ...

s, at altitudes of .

Toxicity and uses

All species of ''Mandragora'' contain highly biologically active

alkaloid Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar ...

s in particular. The different parts of the plant contain different proportions and concentrations of alkaloids, with the roots generally having the highest concentration. Tropane alkaloids are potentially highly toxic. The roots of ''M. caulescens'' contain

hyoscine Scopolamine, also known as hyoscine, or Devil's Breath, is a natural or synthetically produced tropane alkaloid and anticholinergic drug that is formally used as a medication for treating motion sickness and postoperative nausea and vomiti ...

and

anisodamine Anisodamine, also known as 7''β''-hydroxyhyoscyamine, is an anticholinergic and α1 adrenergic receptor antagonist used in the treatment of acute circulatory shock in China. It is given orally or by injection, as a racemic mixture (racanisodam ...

, which are used medicinally in China. The dried roots of ''M. caulescens'' are used in Chinese herbal medicine, and in Yunnan and Xizang as a substitute for

ginseng Ginseng () is the root of plants in the genus ''Panax'', such as Korean ginseng ('' P. ginseng''), South China ginseng ('' P. notoginseng''), and American ginseng ('' P. quinquefolius''), typically characterized by the presence of ginsenosides an ...

References

{{Taxonbar, from=Q1618980 Solanoideae Plants described in 1883