4-Maleylacetoacetate (4-maleylacetoacetatic acid) is an intermediate in the metabolism of

tyrosine -Tyrosine or tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins. It is a non-essential amino acid with a polar side group. The word "tyrosine" is from the Gr ...

. It is converted to fumarylacetoacetate by the

enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...

4-maleylacetoacetate cis-trans-isomerase In enzymology, maleylacetoacetate isomerase () is an enzyme that catalysis, catalyzes the chemical reaction :4-maleylacetoacetate \rightleftharpoons 4-fumarylacetoacetate This enzyme belongs to the family of isomerases, specifically Cis-trans iso ...

. Gluthathione coenzymatically helps in conversion to fumarylacetoacetic acid.

See also