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Malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
in the Land of Israel was a severe
epidemic An epidemic (from Ancient Greek, Greek ἐπί ''epi'' "upon or above" and δῆμος ''demos'' "people") is the rapid spread of disease to a large number of patients among a given population within an area in a short period of time. Epidemics ...
in the region of
Palestine __NOTOC__ Palestine may refer to: * State of Palestine, a state in Western Asia * Palestine (region), a geographic region in Western Asia * Palestinian territories, territories occupied by Israel since 1967, namely the West Bank (including East ...
. The epidemic killed many people from the bible period until it was finally eradicated in the early 1960s. Malaria was originally a large obstacle to
Zionist Zionism ( he, צִיּוֹנוּת ''Tsiyyonut'' after ''Zion'') is a nationalist movement that espouses the establishment of, and support for a homeland for the Jewish people centered in the area roughly corresponding to what is known in Je ...
settlement, because it restricted the land that was usable for settlement, and affected the lifestyle of the Jewish settlers in Palestine. __TOC__


Kligler's anti-malaria campaign

Israel Jacob Kligler Israel Jacob Kligler (24 April 1888 – 23 September 1944) was a microbiologist. A Zionist and humanist, he was born in the Austro-Hungarian Empire, educated in the United States and spent most of his career in Mandatory Palestine, but died b ...
was a microbiologist, a Zionist, and a key contributor to the eradication of malaria in Israel. Malaria was a major factor in morbidity and death in the country, and had important repercussions for Jewish settlement. Before
aliyah Aliyah (, ; he, עֲלִיָּה ''ʿălīyyā'', ) is the immigration of Jews from Jewish diaspora, the diaspora to, historically, the geographical Land of Israel, which is in the modern era chiefly represented by the Israel, State of Israel ...
, Kligler gathered information about the health issues in the country and acquired experience in the field by joining a delegation for the Study of Yellow Fever in South America. Kligler prepared a malaria eradication program that was sent to several organizations and public figures, including Justice Louis Brandeis, who visited the country in 1919 and was shocked by the morbidity of malaria. After failing to convince
Chaim Weizmann Chaim Azriel Weizmann ( he, חיים עזריאל ויצמן ', russian: Хаим Евзорович Вейцман, ''Khaim Evzorovich Veytsman''; 27 November 1874 – 9 November 1952) was a Russian-born biochemist, Zionist leader and Israel ...
and the Zionist executives of the need to invest in the eradication of malaria, Brandeis privately financed $10,000 for an experimental malaria elimination project. This project was directed by Kliger and run through Hadassah Medical Centre. In the Galilee and around Lake Kinnereth (
Sea of Galilee The Sea of Galilee ( he, יָם כִּנֶּרֶת, Judeo-Aramaic: יַמּא דטבריא, גִּנֵּיסַר, ar, بحيرة طبريا), also called Lake Tiberias, Kinneret or Kinnereth, is a freshwater lake in Israel. It is the lowest ...
), malaria had decimated the Jewish settlements, with the incidence rate over 95 percent in 1919. By 1921, Kligler reported that the incidence rate had been cut drastically, with many settlements having no cases at all. Kligler showed the ineffectiveness of previous methods used for the control of malaria in the country, namely, planting of ''
Eucalyptus ''Eucalyptus'' () is a genus of over seven hundred species of flowering trees, shrubs or mallees in the myrtle family, Myrtaceae. Along with several other genera in the tribe Eucalypteae, including '' Corymbia'', they are commonly known as euca ...
'' trees to dry the marshes, and the provision of
Quinine Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to ''Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal leg cr ...
prophylaxis for preventing infection. Kligler focused his studies on the larval stage of the mosquito life-cycle. He studied the prevalence of various ''
Anopheles ''Anopheles'' () is a genus of mosquito first described and named by J. W. Meigen in 1818. About 460 species are recognised; while over 100 can transmit human malaria, only 30–40 commonly transmit parasites of the genus ''Plasmodium'', which c ...
'' species, their biology and nesting grounds, tested different methods of eradication and selected the appropriate measures, taking into account their efficiency and cost. His work demonstrated that drainage of the swamps alone would have had little effect on the malaria, because the mosquitoes breed in little pools of water, which even the most elaborate system of drainage would not have reached. It was subsequently pointed out that at least half of the malaria could be ascribed simply to human carelessness and neglect. This resulted in such an improvement to the quality of the land with respect to malaria and marshes that agriculture could be introduced safely. One of the new method he initiated was the introduction of ''
Gambusia ''Gambusia'' is a large genus of viviparous fish in the family Poeciliidae (order Cyprinodontiformes). ''Gambusia'' contains over 40 species, most of which are principally found in freshwater habitats, though some species may also be found in br ...
'' fish to water sources in the country in 1923. The use of larvivorous fish to diminish mosquito populations was already well known at that time, e.g., the importance lies in the protocols used to define which of the known species of ''Gambusia'' was best suited to the local conditions. The fish effectively reduced the number of mosquito larva surviving into adulthood. The result, combined with drainage techniques, was the almost total eradication of malaria in the upper
Jordan Valley The Jordan Valley ( ar, غور الأردن, ''Ghor al-Urdun''; he, עֵמֶק הַיַרְדֵּן, ''Emek HaYarden'') forms part of the larger Jordan Rift Valley. Unlike most other river valleys, the term "Jordan Valley" often applies just to ...
, i.e. the Huleh area, north of the Sea of Galilee. (Figure 3) The achievements of Kligler and his staff in combating malaria were brought to the attention of the
Health Organization Health, according to the World Health Organization, is "a state of complete physical, mental and social well-being and not merely the absence of disease and infirmity".World Health Organization. (2006)''Constitution of the World Health Organizat ...
, an agency of the
League of Nations The League of Nations (french: link=no, Société des Nations ) was the first worldwide intergovernmental organisation whose principal mission was to maintain world peace. It was founded on 10 January 1920 by the Paris Peace Conference that ...
, the predecessor of the
World Health Organization The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of h ...
, which in May 1925 sent a delegation to Mandatory Palestine. (Figure 4) The delegation gave international recognition to the importance of anti-malarial activity conducted in the country. Kligler lectured on the war against malaria in Mandatory Palestine at the first international malaria conference held in Rome in October 1925; in the lecture he described the main effort is directed towards destruction of breeding places of mosquitoes. In 1927, he founded the "Malaria Research Station" of the Hebrew University in
Rosh Pina Rosh Pina (ראש פינה) is a lay-led independent minyan in Washington, D.C. It meets for Shabbat morning services twice a month in the National Museum of American Jewish Military History (NMAJMH). It also meets occasionally for Friday night a ...
, where pioneering fieldwork was carried out relating to the eradication of malaria. Two years later, he appointed Dr. Gideon Mer as the station manager and together they published a series of articles on malaria.









References

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External links


How the Fight Against Malaria Infected the Future Map of Israel

Review: Epidemiology and Control of Malaria in Palestine

The Epidemiology and Control of Malaria in Palestine

Local Malaria Elimination: A Historical Perspective from Palestine 100 Years Ago Informs the Current Way Forward in Sub-Saharan Africa
*JSTOR: *
Review: Epidemiology and Control of Malaria in Palestine
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Malaria in Rural Settlements in Palestine
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THE MALARIAL FEVERS OF PALESTINE AND THEIR PREVENTION
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Malaria and Rainfall Periodicity in Palestine
Palestine (region) Malaria Epidemics