Magdalena Götz (born 17 January 1962) is a German neuroscientist. She is noted for her study of glial cells and holds a chair at

Ludwig Maximilian University of Munich The Ludwig Maximilian University of Munich (simply University of Munich or LMU; german: Ludwig-Maximilians-Universität München) is a public research university in Munich, Germany. It is Germany's sixth-oldest university in continuous operatio ...

's Department of Physiology. She is involved in the field of adult

neurogenesis Neurogenesis is the process by which nervous system cells, the neurons, are produced by neural stem cells (NSCs). It occurs in all species of animals except the porifera (sponges) and placozoans. Types of NSCs include neuroepithelial cells (NECs) ...

. Götz discovered that glial cells are neural stem cells in the developing mammalian brain. Current investigations study the mechanisms involved in determining how adult neural stem cells are specified. Götz current work focuses on refining ways to reprogram glial cells into neurons in organisms with traumatic brain injury.
The German Stem Cell Network
published a
interview
with Götz in 2015 explaining her research field.

Early life and education

Götz studied Biology between the years 1982 and 1989 at the University of Tübingen, Germany and in Zürich,

Switzerland ). Swiss law does not designate a ''capital'' as such, but the federal parliament and government are installed in Bern, while other federal institutions, such as the federal courts, are in other cities (Bellinzona, Lausanne, Luzern, Neuchâtel ...

. She was promoted in 1992 to the position of

Dr. rer. nat. ''Doctor rerum naturalium'' ( for, , Latin, doctor of natural sciences, lit. 'doctor of the things of nature'), abbreviated Dr. rer. nat., is a doctoral academic degree awarded by universities in some European countries (e.g. Germany, Austria and C ...

at the Friedrich-Miescher Laboratory of the Max-Planck Society, Tübingen. After her promotion and until 1996, she was a postdoctoral fellow at the National Institute for Medical Research, London and Smith Kline Beecham, Harlow.

Career

Götz led an independent Research Group at the Max-Planck Institute of Neurobiology in Martinsried, Munich between 1997 and 2003. She has been the Director of the Institute of Stem Cell Research at th
Helmholtz Center Munich
since 2004. Götz has been chair of Physiological Genomics at the

. Since 2011, Götz has held a Research Professorship at the

. Götz is a member of the Synergy Board as well as a Principal Investigator in th
Münch Cluster for Systems Neurology
also known as Synergy.

Awards and honors

* 2007

Gottfried Wilhelm Leibniz Prize The Gottfried Wilhelm Leibniz Prize (german: link=no, Förderpreis für deutsche Wissenschaftler im Gottfried Wilhelm Leibniz-Programm der Deutschen Forschungsgemeinschaft), in short Leibniz Prize, is awarded by the German Research Foundation to ...

* 2007 Hansen Family Award * 2008 Hans and Ilse Breuer Award * 2010 Order of Merit of the Federal Republic of Germany * 2013 Remedios Caro Almela Prize on Developmental Neurobiology * 2014

Ernst Schering Prize The Ernst Schering Prize is awarded annually by the Ernst Schering Foundation for especially outstanding basic research in the fields of medicine, biology or chemistry anywhere in the world. Established in 1991 by the Ernst Schering Research Found ...

* 2014 Advanced Research Grant by the

European Research Council The European Research Council (ERC) is a public body for funding of scientific and technological research conducted within the European Union (EU). Established by the European Commission in 2007, the ERC is composed of an independent Scientific ...

(ERC) * 2015 Carl-Zeiss Award of the German Society for Cell Biology * 2015 German Stem Cell Network Female Scientist Award * 2016 Prize of the Roger de Spoelberch Foundation * 2018 Schellenberg Award

Publications

Access the complete list of Götz's publication
here
* Falkner S*, Grade S*, Dimou L, Conzelmann K-K, Bonhoeffer T, Götz M*, Hübener M*
Transplanted embryonic neurons integrate into adult neocortical circuits
Nature 539:248-53 (2016) * Gascón S*, Murenu E*, Masserdotti G, Ortega F, Russo GL, Petrik D, Deshpande A, Heinrich C, Karow M, Robertson SP, Schroeder T, Beckers J, Irmler M, Berndt C, Angeli JP, Conrad M, Berninger B, Götz M
Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming
Cell Stem Cell 18:396-409 (2016) * Masserdotti G*, Gillotin S*, Sutor B, Drechsel D, Irmler M, Jørgensen HF, Sass S, Theis FJ, Beckers J, Berninger B, Guillemot F*, Götz M*
Transcriptional mechanisms of proneural factors and REST in regulating neuronal reprogramming of astrocytes
Cell Stem Cell 17:74-88 (2015) * Ninkovic J, Steiner-Mezzadri A, Jawerka M, Akinci U, Masserdotti G, Petricca S, Fischer J, von Holst A, Beckers J, Lie CD, Petrik D, Miller E, Tang J, Wu J, Lefebvre V, Demmers J, Eisch A, Mezger D, Crabtree G, Irmler M, Poot R, Götz M
The BAF complex interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network.
Cell Stem Cell 13:403-18 (2013) * Stahl R, Walcher T, De Juan Romeo C, Pilz GA, Cappello S, Irmler M, Sanz Anquela JM, Beckers J, Blum R, Borrell V, Götz M
Trnp1 regulates expansion and folding of the mammalian cerebral cortex by control of radial glial fate.
Cell 153:535-49 (2013) * Sirko S*, Behrendt G*, Johansson P, Tripathi P, Costa M, Bek S, Heinrich C, Tiedt S, Colak D, Dichgans M, Fischer IR, Plesnila N, Staufenbiel M, Haass C, Snapyan M, Saghatelyan A, Tsai L-H, Fischer A, Grobe K, Dimou L, Götz M
Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog
Cell Stem Cell 12:426-39 (2013) * Bardehle S, Krüger M, Schwausch J, Ninkovic J, Clevers H, Snippert HJ, Buggenthin F, Theis FJ, Meyer-Luehmann M, Bechmann, Dimou L, Götz M
Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation.
Nature Neuroscience 16:580-6 (2013) * Cappello S, Böhringer CRJ, Bergami M, Conzelmann K-K, Ghanem A, Tomassy GS, Arlotta P, Mainardi M, Allegra M, Caleo M, van Hengel J, Brakebusch C, Götz M
A radial glia specific role of RhoA in double-cortex formation
Neuron 73:911-24 (2012) * Beckervordersandforth R, Tripathi P, Ninkovic J, Bayam E, Lepier A, Stempfhuber B, Kirchhoff F, Hirrlinger J, Haslinger A, Chichung LD, Beckers J, Yoder B, Irmler M, Götz M
In vivo fate mapping and expression analysis reveals unique molecular hallmarks of prospectively isolated adult neural stem cells.
Cell Stem Cell 7:744-58 (2010) * Buffo A, Rite I, Tripathi P, Lepier A, Colak D, Horn A-P, Mori T, Götz M. Origin and progeny of reactive gliosis
A source of multipotent cells in the injured brain.
PNAS 105:3581-86 (2008)

References

{{DEFAULTSORT:Gotz, Magdalena German neuroscientists German women neuroscientists Gottfried Wilhelm Leibniz Prize winners Academic staff of the Ludwig Maximilian University of Munich Recipients of the Cross of the Order of Merit of the Federal Republic of Germany Living people 1962 births