Macelignan
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Macelignan (Anwulignan) is a lignan. It can be found in ''
Myristica fragrans ''Myristica fragrans'' is an evergreen tree indigenous to the Maluku Islands of Indonesia. It is important as the main source of the spices nutmeg and mace. It is widely grown across the tropics including Guangdong and Yunnan in China, Taiwan, I ...
'', the nutmeg.


Medical research

One study has shown that macelignan may exert antimicrobial and anti
cariogenic Tooth decay, also known as cavities or caries, is the breakdown of teeth due to acids produced by bacteria. The cavities may be a number of different colors from yellow to black. Symptoms may include pain and difficulty with eating. Complicatio ...
activity against ''
Streptococcus mutans ''Streptococcus mutans'' is a facultatively anaerobic, gram-positive coccus (round bacterium) commonly found in the human oral cavity and is a significant contributor to tooth decay. It is part of the " streptococci" (plural, non-italic lowercase ...
'', but this is not a currently used treatment. Macelignan may also act as an antidiabetic molecule via PPAR signaling and upregulate adipocyte gene expression Macelignan may contain antioxidant and anti-inflammatory properties and is marketed in breast enhancement creams for its anti-aging properties.


References

Lignans Methoxy compounds {{aromatic-stub