The Mycobacterial 4 TMS Phage Holin (MP4 Holin) Family
TC# 1.E.40 is a group of
transporters belonging to
Holin superfamily IV The Holin superfamily IV is a superfamily of integral membrane transport proteins. It is one of the seven different holin superfamilies in total.
The Holin superfamily IV includes the TC families:
1.E.10- The ''Bacillus subtilis'' φ29 Holin (φ ...
. A representative list of members belonging to the MP4 holin family can be found in the Transporter Classification Database.
A member of the Mycobacterial 4 transmembrane segment (TMS) Phage Holin family was first identified by Catalao ''et al.'' This small family includes several 4 TMS homologues, from
mycobacterial
''Mycobacterium'' is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis ('' M. tuberculosis'') and ...
phage and
cyanobacteria
Cyanobacteria (), also known as Cyanophyta, are a phylum of gram-negative bacteria that obtain energy via photosynthesis. The name ''cyanobacteria'' refers to their color (), which similarly forms the basis of cyanobacteria's common name, blu ...
.
See also
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Holin
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Lysin
Lysins, also known as endolysins or murein hydrolases, are hydrolytic enzymes produced by bacteriophages in order to cleave the host's cell wall during the final stage of the lytic cycle. Lysins are highly evolved enzymes that are able to target ...
*
Transporter Classification Database
References
Holins
Protein families
{{Membrane-protein-stub