MIMT1
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In molecular biology, MER1 repeat containing imprinted transcript 1 (non-protein coding), also known as MIMT1 is a
long non-coding RNA Long non-coding RNAs (long ncRNAs, lncRNA) are a type of RNA, generally defined as transcripts more than 200 nucleotides that are not translated into protein. This arbitrary limit distinguishes long ncRNAs from small non-coding RNAs, such as mic ...
. It is an imprinted gene, which is paternally expressed. Deletion of this
gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
is lethal in
cattle Cattle (''Bos taurus'') are large, domesticated, cloven-hooved, herbivores. They are a prominent modern member of the subfamily Bovinae and the most widespread species of the genus ''Bos''. Adult females are referred to as cows and adult mal ...
, causing still births and
abortions Abortion is the termination of a pregnancy by removal or expulsion of an embryo or fetus. An abortion that occurs without intervention is known as a miscarriage or "spontaneous abortion"; these occur in approximately 30% to 40% of pregnan ...
. It is lethal in 85% of individuals with the deletion, it is thought that incomplete
silencing Silencing is a visual illusion in which a set of objects that change iluminancehuealleles allows some individuals with the deletion to survive.


See also

* Long noncoding RNA


References

{{reflist Non-coding RNA