E3 ubiquitin-protein ligase MIB1 is an
enzyme that in humans is encoded by the ''MIB1''
gene.
It is involved in regulating
apoptosis
Apoptosis (from grc, ἀπόπτωσις, apóptōsis, 'falling off') is a form of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes incl ...
.
Confusion with proliferative marker
An
antibody directed at the protein
Ki-67, a product of the
MKI67 gene, is called ''MIB-1''.
[MIB-1. Veripath OncoDiagnostics]
http://www.oncodx.org/onco/mib_1.htm
. Accessed on: April 24, 2009.
References
Further reading
*
*
*
*
*
*
*
*
*
*
*
*
*
{{gene-18-stub