Homeobox protein Meis1 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the MEIS1
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Function
Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins.
Interactions
MEIS1 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with
PBX1
Pre-B-cell leukemia transcription factor 1 is a protein that in humans is encoded by the ''PBX1'' gene.
Interactions
PBX1 has been shown to Protein-protein interaction, interact with:
* HOXB1,
* HOXB7,
* MEIS1, and
* PKNOX1, Prep1.
Referen ...
and
HOXA9
Homeobox protein Hox-A9 is a protein that in humans is encoded by the ''HOXA9'' gene.
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromoso ...
.
References
Further reading
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External links
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Transcription factors
{{gene-2-stub