Lysophospholipid acyltransferase 7 also known as membrane-bound O-acyltransferase domain-containing protein 7 (MBOAT7) is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
that in humans is encoded by the MBOAT7
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
It is homologous to other
membrane-bound O-acyltransferases.
Function
This gene encodes a member of the membrane-bound O-
acyltransferase
Acyltransferase is a type of transferase enzyme that acts upon acyl groups.
Examples include:
* Glyceronephosphate O-acyltransferase
* Lecithin-cholesterol acyltransferase
*Long-chain-alcohol O-fatty-acyltransferase
In enzymology, a long-chain- ...
s family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the re-
acylation
In chemistry, acylation (or alkanoylation) is the chemical reaction in which an acyl group () is added to a compound. The compound providing the acyl group is called the acylating agent.
Because they form a strong electrophile when treated with ...
of
phospholipid
Phospholipids, are a class of lipids whose molecule has a hydrophilic "head" containing a phosphate group and two hydrophobic "tails" derived from fatty acids, joined by an alcohol residue (usually a glycerol molecule). Marine phospholipids typ ...
s as part of the phospholipid remodeling pathway known as the Land cycle.
References
Further reading
*
*
*
*
*
{{gene-19-stub