Lanugo is very thin, soft, usually unpigmented, downy

hair Hair is a protein filament that grows from follicles found in the dermis. Hair is one of the defining characteristics of mammals. The human body, apart from areas of glabrous skin, is covered in follicles which produce thick terminal and f ...

that is sometimes found on the body of a fetus or

newborn An infant or baby is the very young offspring of human beings. ''Infant'' (from the Latin word ''infans'', meaning 'unable to speak' or 'speechless') is a formal or specialised synonym for the common term ''baby''. The terms may also be used to ...

. It is the first hair to be produced by the fetal hair follicles, and it usually appears around sixteen weeks of gestation and is abundant by week twenty. It is normally shed before birth, around seven or eight months of gestation, but is sometimes present at birth. It disappears on its own within a few weeks. It is replaced by hair covering the same surfaces, which is called

vellus hair Vellus hair is short, thin, light-colored, and barely noticeable hair that develops on most of a human’s body during childhood. Exceptions include the lips, the back of the ear, the palm of the hand, the sole of the foot, some external genital ...

. This hair is thinner and more difficult to see. The more visible hair that persists into adulthood is called

terminal hair In humans, terminal hair is a variant of hair that is thick and long such as what grows on the scalp, as compared with vellus hair, colloquially known as peach fuzz, growing elsewhere.Marks, James G; Miller, Jeffery (2006)''Lookingbill and M ...

. It forms in specific areas and is

hormone A hormone (from the Greek participle , "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs by complex biological processes to regulate physiology and behavior. Hormones are required ...

-dependent. The term is from the

Latin Latin (, or , ) is a classical language belonging to the Italic branch of the Indo-European languages. Latin was originally a dialect spoken in the lower Tiber area (then known as Latium) around present-day Rome, but through the power of the ...

lana Lana may refer to: *Lana (given name) *Francesco Lana de Terzi (1631–1687), Italian Jesuit priest and scientist *Lana (wrestler), professional wrestler and pro wrestling manager *''Wild Energy. Lana'', a 2006 Ukrainian fantasy novel Sciences *L ...

'', meaning "wool."

Humans

Fetal development

During human development, the lanugo grows on

fetus A fetus or foetus (; plural fetuses, feti, foetuses, or foeti) is the unborn offspring that develops from an animal embryo. Following embryonic development the fetal stage of development takes place. In human prenatal development, fetal deve ...

es as a normal part of

gestation Gestation is the period of development during the carrying of an embryo, and later fetus, inside viviparous animals (the embryo develops within the parent). It is typical for mammals, but also occurs for some non-mammals. Mammals during pregna ...

, but it is usually shed and replaced by

at about thirty-three to thirty-six weeks of

gestational age In obstetrics, gestational age is a measure of the age of a pregnancy which is taken from the beginning of the woman's last menstrual period (LMP), or the corresponding age of the gestation as estimated by a more accurate method if available. Su ...

. As the lanugo is shed from the skin, it is normal for the hair to be consumed by the developing fetus, since it drinks from the

amniotic fluid The amniotic fluid is the protective liquid contained by the amniotic sac of a gravid amniote. This fluid serves as a cushion for the growing fetus, but also serves to facilitate the exchange of nutrients, water, and biochemical products betwee ...

and urinates into its environment. As a result, lanugo contributes to the new-born baby's meconium. The presence of lanugo on new-borns is not necessarily a sign of

premature birth Preterm birth, also known as premature birth, is the birth of a baby at fewer than 37 weeks gestational age, as opposed to full-term delivery at approximately 40 weeks. Extreme preterm is less than 28 weeks, very early preterm birth is between 2 ...

, as it is also seen on infants born at thirty-nine weeks of gestation (full term). Lanugo functions as an anchor to hold the

vernix caseosa Vernix caseosa, also known as vernix or birthing custard, is the waxy white substance found coating the skin of newborn human babies. It is produced by dedicated cells and is thought to have some protective roles during fetal development and for ...

on the skin. Together they protect the delicate fetal skin from being damaged by the amniotic fluid. The vernix caseosa also helps to prepare the fetus for life outside the womb. It provides lubrication for birth and contributes to thermoregulation, prevention of water loss, and innate immunity. Without the lanugo to anchor the vernix caseosa, these functions would be compromised.

Malnutrition

In the absence of

fat In nutrition science, nutrition, biology, and chemistry, fat usually means any ester of fatty acids, or a mixture of such chemical compound, compounds, most commonly those that occur in living beings or in food. The term often refers spec ...

, lanugo grows to serve as a replacement insulator, and thus can be observed in malnourished patients, including those with eating disorders. When found along with other physical symptoms, for example, lanugo can help a physician make a diagnosis of

anorexia nervosa Anorexia nervosa, often referred to simply as anorexia, is an eating disorder characterized by low weight, food restriction, body image disturbance, fear of gaining weight, and an overpowering desire to be thin. ''Anorexia'' is a term of Gr ...

bulimia nervosa Bulimia nervosa, also known as simply bulimia, is an eating disorder characterized by binge eating followed by purging or fasting, and excessive concern with body shape and weight. The aim of this activity is to expel the body of calories eate ...

Teratoma

It is often found in

teratoma A teratoma is a tumor made up of several different types of tissue, such as hair, muscle, teeth, or bone. Teratomata typically form in the ovary, testicle, or coccyx. Symptoms Symptoms may be minimal if the tumor is small. A testicular terato ...

s (congenital tumours).

Other mammals

Lanugo is also common on other

mammals Mammals () are a group of vertebrate animals constituting the class Mammalia (), characterized by the presence of mammary glands which in females produce milk for feeding (nursing) their young, a neocortex (a region of the brain), fur or ...

. For example, seals and elephants are often born with a covering of lanugo. Some species of fetal whales and dolphins also have lanugo.

References

External links

{{Authority control Human hair Neonatology