Lusutrombopag, sold under the brand name Mulpleta among others, is a medication that has been developed for certain conditions that lead to thrombocytopenia (abnormally low platelet counts) such as thrombocytopenia associated with chronic liver disease in patients prior to elective invasive procedures. It is being manufactured and marketed in Japan by Shionogi. It was approved by the U.S. Food and Drug Administration (FDA) in July 2018, and NICE in January 2020. It was approved for medical use in the European Union in February 2019.

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* Drugs acting on the blood and blood forming organs Orphan drugs Thrombopoietin receptor agonists Thiazoles Chloroarenes Carboxylic acids Japanese inventions Carboxamides Ethers {{blood-drug-stub