Lung volumes and lung capacities refer to the
volume
Volume is a measure of occupied three-dimensional space. It is often quantified numerically using SI derived units (such as the cubic metre and litre) or by various imperial or US customary units (such as the gallon, quart, cubic inch). The de ...
of
air
The atmosphere of Earth is the layer of gases, known collectively as air, retained by Earth's gravity that surrounds the planet and forms its planetary atmosphere. The atmosphere of Earth protects life on Earth by creating pressure allowing f ...
in the
lung
The lungs are the primary organs of the respiratory system in humans and most other animals, including some snails and a small number of fish. In mammals and most other vertebrates, two lungs are located near the backbone on either side of t ...
s at different phases of the
respiratory cycle.
The average total lung capacity of an adult human male is about 6
litres
The litre (international spelling) or liter (American English spelling) (SI symbols L and l, other symbol used: â„“) is a metric unit of volume. It is equal to 1 cubic decimetre (dm3), 1000 cubic centimetres (cm3) or 0.001 cubic metre (m3). ...
of air.
Tidal breathing is normal, resting breathing; the
tidal volume
Tidal volume (symbol VT or TV) is the volume of air moved into or out of the lungs during a normal breath. In a healthy, young human adult, tidal volume is approximately 500 ml per inspiration or 7 ml/kg of body mass.
Mechanical vent ...
is the volume of air that is inhaled or exhaled in only a single such breath.
The average human
respiratory rate
The respiratory rate is the rate at which breathing occurs; it is set and controlled by the respiratory center of the brain. A person's respiratory rate is usually measured in breaths per minute.
Measurement
The respiratory rate in humans is mea ...
is 30–60 breaths per minute at birth,
decreasing to 12–20 breaths per minute in adults.
Factors affecting volumes
Several factors affect lung volumes; some can be controlled, and some cannot be controlled. Lung volumes vary with different people as follows:
A person who is born and lives at
sea level
Mean sea level (MSL, often shortened to sea level) is an average surface level of one or more among Earth's coastal bodies of water from which heights such as elevation may be measured. The global MSL is a type of vertical datuma standardised g ...
will develop a slightly smaller lung capacity than a person who spends their life at a high
altitude
Altitude or height (also sometimes known as depth) is a distance measurement, usually in the vertical or "up" direction, between a reference datum and a point or object. The exact definition and reference datum varies according to the context ...
. This is because the partial pressure of oxygen is lower at higher altitude which, as a result means that oxygen less readily diffuses into the bloodstream. In response to higher altitude, the body's diffusing capacity increases in order to process more air. Also, due to the lower environmental air pressure at higher altitudes, the air pressure within the breathing system must be lower in order to inhale; in order to meet this requirement, the thoracic diaphragm has a tendency to lower to a greater extent during inhalation, which in turn causes an increase in lung volume.
When someone living at or near sea level travels to locations at high altitudes (e.g. the
Andes
The Andes, Andes Mountains or Andean Mountains (; ) are the longest continental mountain range in the world, forming a continuous highland along the western edge of South America. The range is long, wide (widest between 18°S – 20°S ...
;
Denver, Colorado
Denver () is a consolidated city and county, the capital, and most populous city of the U.S. state of Colorado. Its population was 715,522 at the 2020 census, a 19.22% increase since 2010. It is the 19th-most populous city in the Unit ...
;
Tibet
Tibet (; ''Böd''; ) is a region in East Asia, covering much of the Tibetan Plateau and spanning about . It is the traditional homeland of the Tibetan people. Also resident on the plateau are some other ethnic groups such as Monpa people, ...
; the
Himalayas
The Himalayas, or Himalaya (; ; ), is a mountain range in Asia, separating the plains of the Indian subcontinent from the Tibetan Plateau. The range has some of the planet's highest peaks, including the very highest, Mount Everest. Over 100 ...
) that person can develop a condition called
altitude sickness
Altitude sickness, the mildest form being acute mountain sickness (AMS), is the harmful effect of high altitude, caused by rapid exposure to low amounts of oxygen at high elevation. People can respond to high altitude in different ways. Sympt ...
because their lungs remove adequate amounts of carbon dioxide but they do not take in enough oxygen. (In normal individuals, carbon dioxide is the primary determinant of respiratory drive.)
Lung function development is reduced in children who grow up near motorways
although this seems at least in part reversible. Air pollution exposure affects FEV
1 in asthmatics, but also affects FVC and FEV
1 in healthy adults even at low concentrations.
Specific changes in lung volumes also occur during pregnancy.
Functional residual capacity
Functional residual capacity (FRC) is the volume of air present in the lungs at the end of passive expiration. At FRC, the opposing elastic recoil forces of the lungs and chest wall are in equilibrium and there is no exertion by the diaphragm ...
drops 18–20%,
typically falling from 1.7 to 1.35 litres, due to the compression of the
diaphragm by the uterus. The compression also causes a decreased
total lung capacity
Lung volumes and lung capacities refer to the volume of air in the lungs at different phases of the respiratory cycle.
The average total lung capacity of an adult human male is about 6 litres of air.
Tidal breathing is normal, resting breathi ...
(TLC) by 5%
and decreased
expiratory reserve volume
Lung volumes and lung capacities refer to the volume of air in the lungs at different phases of the respiratory cycle.
The average total lung capacity of an adult human male is about 6 litres of air.
Tidal breathing is normal, resting breath ...
by 20%.
Tidal volume
Tidal volume (symbol VT or TV) is the volume of air moved into or out of the lungs during a normal breath. In a healthy, young human adult, tidal volume is approximately 500 ml per inspiration or 7 ml/kg of body mass.
Mechanical vent ...
increases by 30–40%, from 0.5 to 0.7 litres,
and
minute ventilation
Minute ventilation (or respiratory minute volume or minute volume) is the volume of gas inhaled (inhaled minute volume) or exhaled (exhaled minute volume) from a person's lungs per minute. It is an important parameter in respiratory medicine du ...
by 30–40%
giving an increase in pulmonary ventilation. This is necessary to meet the increased oxygen requirement of the body, which reaches 50 ml/min, 20 ml of which goes to reproductive tissues. Overall, the net change in maximum breathing capacity is zero.
Values
The ''tidal volume'', ''vital capacity'', ''inspiratory capacity'' and ''expiratory reserve volume'' can be measured directly with a
spirometer
A spirometer is an apparatus for measuring the volume of air inspired and expired by the lungs. A spirometer measures ventilation, the movement of air into and out of the lungs. The spirogram will identify two different types of abnormal ventilat ...
. These are the basic elements of a ventilatory ''
pulmonary function test
Pulmonary function testing (PFT) is a complete evaluation of the respiratory system including patient history, physical examinations, and tests of pulmonary function. The primary purpose of pulmonary function testing is to identify the severity ...
''.
Determination of the ''residual volume'' is more difficult as it is impossible to "completely" breathe out. Therefore, measurement of the residual volume has to be done via indirect methods such as radiographic planimetry,
body plethysmography
A plethysmograph is an instrument for measuring changes in volume within an organ or whole body (usually resulting from fluctuations in the amount of blood or air it contains). The word is derived from the Greek "plethysmos" (increasing, enla ...
, closed circuit dilution (including the
helium dilution technique
The helium dilution technique is the way of measuring the functional residual capacity of the lungs (the volume left in the lungs after normal expiration).
This technique is a closed-circuit system where a spirometer is filled with a mixture o ...
) and
nitrogen washout
Nitrogen washout (or Fowler's method) is a test for measuring anatomic dead space in the lung during a respiratory cycle, as well as some parameters related to the closure of airways.
Procedure
A nitrogen washout can be performed with a single n ...
.
In absence of such, estimates of ''residual volume'' have been prepared as a proportion of body mass for infants (18.1 ml/kg), or as a proportion of ''vital capacity'' (0.24 for men and 0.28 for women) or in relation to height and age ((0.0275* Age
ears
An ear is the organ that enables hearing and, in mammals, body balance using the vestibular system. In mammals, the ear is usually described as having three parts—the outer ear, the middle ear and the inner ear. The outer ear consists o ...
0.0189*Height
mˆ’2.6139) litres for normal-mass individuals and (0.0277*Age
ears
An ear is the organ that enables hearing and, in mammals, body balance using the vestibular system. In mammals, the ear is usually described as having three parts—the outer ear, the middle ear and the inner ear. The outer ear consists o ...
0.0138*Height
mˆ’2.3967) litres for overweight individuals). Standard errors in prediction equations for residual volume have been measured at 579 ml for men and 355 ml for women, while the use of 0.24*FVC gave a standard error of 318 ml.
Online calculators are availablethat can compute predicted lung volumes, and other spirometric parameters based on a patient's age, height, weight, and ethnic origin for many reference sources.
British rower and three-time Olympic gold medalist,
Pete Reed
Peter K. Reed OBE (born 27 July 1981) is a retired British Olympic rower. Reed is a three-times Olympic gold medallist – earning gold in the Men's coxless four at the 2008 and 2012 Olympics, and then a gold medal in the Men's eight at the 2 ...
, is reported to hold the largest recorded lung capacity of 11.68 litres;
US swimmer,
Michael Phelps
Michael Fred Phelps II (born June 30, 1985) is an American former competitive swimmer. He is the most successful and most decorated Olympian of all time with a total of 28 medals. Phelps also holds the all-time records for Olympic gold me ...
is also said to have a lung capacity of around 12 litres.
Weight of breath
The mass of one breath is approximately a gram (0.5-5 g). A litre of air weighs about 1.2 g (1.2 kg/m
3).
[ Atmosphere of Earth#Density and mass] A half litre ordinary tidal breath
weighs 0.6 g; a maximal 4.8 litre breath (average vital capacity for males)
weighs approximately 5.8 g.
Restrictive and obstructive
![Lung volumes in restricted, normal and obstructed lung](https://upload.wikimedia.org/wikipedia/commons/f/fd/Lung_volumes_in_restricted%2C_normal_and_obstructed_lung.jpg)
The results (in particular
FEV1/FVC and FRC) can be used to distinguish between restrictive and obstructive pulmonary diseases:
See also
*
Pulmonary function testing
Pulmonary function testing (PFT) is a complete evaluation of the respiratory system including patient history, physical examinations, and tests of pulmonary function. The primary purpose of pulmonary function testing is to identify the severity ...
(PFT)
*
Spirometry
References
External links
Lung function fundamentals (anaesthetist.com)Volume of human lungs
{{Respiratory physiology
Respiratory physiology
Pulmonary function testing