Luisa Massimo
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Luisa Massimo (22 December 1928 – 5 October 2016) was an
Italian Italian(s) may refer to: * Anything of, from, or related to the people of Italy over the centuries ** Italians, an ethnic group or simply a citizen of the Italian Republic or Italian Kingdom ** Italian language, a Romance language *** Regional Ita ...
pediatrician Pediatrics ( also spelled ''paediatrics'' or ''pædiatrics'') is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, paediatrics covers many of their youth until the ...
. From 1972 to 1997 she was the director of the 4th Division of Pediatrics (
Hematology Hematology ( always spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood. It involves treating diseases that affect the produc ...
and
Oncology Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ó ...
) of the Children's Hospital
Istituto Giannina Gaslini The Istituto Giannina Gaslini is the biggest pediatric hospital of North Italy, located in Genoa, Genoa Quarto dei Mille and founded by the Italian industrialist, politician and phylanthropist Gerolamo Gaslini (Count of Saint Jerome) in 1938. It ...
of Genoa. From 1998 she is director emeritus. She is internationally considered one of the founders of
Pediatric oncology Childhood cancer is cancer in a child. About 80% of childhood cancer cases can be successfully treated thanks to modern medical treatments and optimal patient care. However, only about 10% of children diagnosed with cancer reside in high-income cou ...
Since April 2003 she was consultant of Pediatric Psycho-Oncology and International Affairs. Since 1996 she is Expert Evaluator in Ethics and Clinical Bioethics of the
European Commission The European Commission (EC) is the executive of the European Union (EU). It operates as a cabinet government, with 27 members of the Commission (informally known as "Commissioners") headed by a President. It includes an administrative body o ...
. She taught Pediatric Oncology and Pediatric Hematology at the graduate schools of Pediatrics, of Hematology and of Oncology in the
University of Genoa The University of Genoa, known also with the acronym UniGe ( it, Università di Genova), is one of the largest universities in Italy. It is located in the city of Genoa and regional Metropolitan City of Genoa, on the Italian Riviera in the Liguri ...
. From 1986 to 1994 she was President of the "IST-National Institute for cancer research” in Genoa. A member of several scientific commissions (national and international), she has published 300 scientific works including 220 indexed on
PubMed PubMed is a free search engine accessing primarily the MEDLINE database of references and abstracts on life sciences and biomedical topics. The United States National Library of Medicine (NLM) at the National Institutes of Health maintain the ...
. She is an honorary citizen of
Baltimore Baltimore ( , locally: or ) is the List of municipalities in Maryland, most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic (United States), Mid-Atlantic, and List of United States cities by popula ...
(United States), of
La Paz La Paz (), officially known as Nuestra Señora de La Paz (Spanish pronunciation: ), is the seat of government of the Bolivia, Plurinational State of Bolivia. With an estimated 816,044 residents as of 2020, La Paz is the List of Bolivian cities ...
in Bolivia, of
Bogotá Bogotá (, also , , ), officially Bogotá, Distrito Capital, abbreviated Bogotá, D.C., and formerly known as Santa Fe de Bogotá (; ) during the Spanish period and between 1991 and 2000, is the capital city of Colombia, and one of the larges ...
in Colombia, and
Rochefort-du-Gard Rochefort-du-Gard is a commune in the Gard department in southern France. Population Culture Rochefort-du-Gard is integrated into Occitanie but naturally rooted in Provence. It depends on the economic area of Avignon. With its 42 associatio ...
in France. She received numerous awards: among them, in 1971 the "Gianni Pauletta" for Oncology, by the
Accademia Nazionale dei Lincei The Accademia dei Lincei (; literally the "Academy of the Lynx-Eyed", but anglicised as the Lincean Academy) is one of the oldest and most prestigious European scientific institutions, located at the Palazzo Corsini on the Via della Lungara in Rom ...
, in 1991 the "American Italian Cancer Foundation's Prize for Scientific Excellence in Medicine" in New York City, in 2004 she was decorated with the Gold Medal of Italian Republic for merit of public health (Rome, Quirinale), in 2011 with the Gold Medal “Master of Pediatrics" by the Italian Society of Pediatrics.


Family and education

But in my heart, looking in the mirror the days of my life, the people I have met in any part of the world, efforts to honor the values I believe in, the choice of medicine as the reason of my life and the desire to spend myself for the youngest patients and less curable, I feel that my parents and the type of education they gave me are the basis of everything I was able to realize and appreciate
The Massimo family after the
First World War World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fightin ...
was spread over several continents. Only her father settled in Genoa. They have deep roots, from
Veneto Veneto (, ; vec, Vèneto ) or Venetia is one of the 20 regions of Italy. Its population is about five million, ranking fourth in Italy. The region's capital is Venice while the biggest city is Verona. Veneto was part of the Roman Empire unt ...
and
Piedmont it, Piemontese , population_note = , population_blank1_title = , population_blank1 = , demographics_type1 = , demographics1_footnotes = , demographics1_title1 = , demographics1_info1 = , demographics1_title2 ...
to the United States, South Africa, several countries in Europe and South America. Luisa Massimo's great-grandfather Giovanni Battista Mantovani studied Medicine at the end of the 18th century at the
University of Padua The University of Padua ( it, Università degli Studi di Padova, UNIPD) is an Italian university located in the city of Padua, region of Veneto, northern Italy. The University of Padua was founded in 1222 by a group of students and teachers from B ...
, and practiced in
Rovigo Rovigo (, ; egl, Ruig) is a city and ''comune'' in the Veneto region of Northeast Italy, the capital of the eponymous province. Geography Rovigo stands on the low ground known as Polesine, by rail southwest of Venice and south-southwest of P ...
. The grandfather Diodato Massimo was a painter, graduated at the famous Academia of
Venice Venice ( ; it, Venezia ; vec, Venesia or ) is a city in northeastern Italy and the capital of the Veneto Regions of Italy, region. It is built on a group of 118 small islands that are separated by canals and linked by over 400  ...
. Living at the Court of
Vienna en, Viennese , iso_code = AT-9 , registration_plate = W , postal_code_type = Postal code , postal_code = , timezone = CET , utc_offset = +1 , timezone_DST ...
, he was considered a traitor and in 1914 interned at the Lager of Katzenau in Austria with most of his family. After his death he received great honors, a street and the conference room of the Library of Badia Polesine where he was born were named after him. Two of his paintings are exhibited at the Österreichische Galerie Belvedere in Vienna art museum. Her father was born in Trento, and was a great lover of classical music since his youth. After internment at Katzenau during the First World War, he was enlisted in the Inter-Allied Commission, and remained at the Italian diplomatic service until 1923. Graduated in design, he wrote a number of articles of historical and political interest in Italy and Germany. The Piedmontese mother, despite humble beginnings, cultivated studies becoming a primary school teacher. They married in Turin on April 3, 1926. Luisa Maria Elena Massimo was born on December 22, 1928. In 1931 her sister Elena Maria Laura was born. In 1933 the father won the tender for the construction of the Institute Giannina Gaslini, defining event for the economy of the family business of building materials. In 1935 Germany began the race first persecution of the Jews and family Massimo was a lifeline for many of them. On March 13, 1938 the Nazis occupied Vienna and began the Holocaust. This tragic event also touched the family of Luisa Massimo. During the
Second World War World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...
they moved in a village of the Riviera. In those years, Luisa decided to study
medicine Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care pract ...
.


Medical studies

The journalist and friend Pier Luigi Bagatin of the University Cà Foscari of Venice, writes about the professional choice of Luisa Massimo:
One day in 1942, a young girl 14 years old makes a deal with herself under the olive trees on a hill watching the sea and the coast of Portofino. If she will survive the war, she would study medicine, she wished to become a good doctor devoted to research. Just to reach her objective she promised herself to be alone
In 1947 she entered the Faculty of Medicine in Genoa. Completed the first year, she took part to the fifteen-day meeting of the European youth in Germany. She continued her studies in Genoa, but she could integrate them each year from July to December at the
London University The University of London (UoL; abbreviated as Lond or more rarely Londin in post-nominals) is a federal public research university located in London, England, United Kingdom. The university was established by royal charter in 1836 as a degree- ...
. Luisa was the first foreign student to ask to attend the London University. She was assigned to the second year of Medicine at St. Mary's Hospital in
Paddington Paddington is an area within the City of Westminster, in Central London. First a medieval parish then a metropolitan borough, it was integrated with Westminster and Greater London in 1965. Three important landmarks of the district are Paddi ...
, becoming a student also of
Alexander Fleming Sir Alexander Fleming (6 August 1881 – 11 March 1955) was a Scottish physician and microbiologist, best known for discovering the world's first broadly effective antibiotic substance, which he named penicillin. His discovery in 1928 of w ...
, who was then Emeritus, but still active. To live in London offered her another opportunity: she met
Winston Churchill Sir Winston Leonard Spencer Churchill (30 November 187424 January 1965) was a British statesman, soldier, and writer who served as Prime Minister of the United Kingdom twice, from 1940 to 1945 Winston Churchill in the Second World War, dur ...
as a painter both of the English country and of Morocco. In London she applied for a rotating internship in the United States, to start soon after the end of the Medical studies. On 20 July 1953 she graduated cum laude discussing an experimental thesis on one of the first anticancer drugs. Few days after, from the Port of Genoa she left for the United States and started to work at the
Woman's Medical College of Pennsylvania The Woman's Medical College of Pennsylvania (WMCP) was founded in 1850, and was the second medical institution in the world established to train women in medicine to earn the M.D. degree. The New England Female Medical College had been established ...
in
Philadelphia Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Sinc ...
. She attended also the famous "Children's Hospital" by participating to several meetings. She became also member of the
Medical Women's International Association The Medical Women's International Association is a non-governmental organization founded in 1919 with the purpose of representing female physicians worldwide. Esther Lovejoy was its first president. The Association grew from an international mee ...
. After a year in Philadelphia she attended for a month the pediatric ward of
The Johns Hopkins University School of Medicine The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a Private university, private research university in Baltimore, Maryland. Founded in 1893, the School of Medicine shares a campus with the ...
in Baltimore.


Clinical and scientific career

With this cultural baggage she returned at Gaslini in Genoa. She focused the postgraduate School of Pediatrics in a year. She specialized on 1955 with 60/60 cum laude with a thesis of experimental Oncology. In 1958 she was assigned by Professor
Giovanni De Toni Giovanni may refer to: * Giovanni (name), an Italian male given name and surname * Giovanni (meteorology), a Web interface for users to analyze NASA's gridded data * ''Don Giovanni'', a 1787 opera by Wolfgang Amadeus Mozart, based on the legend of ...
of a scholarship funded by the Italian Ministry of Health, to attend the first International Course of
Pediatric Oncology Childhood cancer is cancer in a child. About 80% of childhood cancer cases can be successfully treated thanks to modern medical treatments and optimal patient care. However, only about 10% of children diagnosed with cancer reside in high-income cou ...
in
Paris Paris () is the capital and most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), making it the 30th most densely populated city in the world in 2020. S ...
. Back from Paris at the end of 1959, she was entrusted with the task to take care of children with
leukemia Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ' ...
and
cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...
. Charlotte Tan, professor at the
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in the borough of Manhattan in New York City, founded in 1884 as the New York Cancer Hospital. MSKCC is one of 52 National Cancer Institute– ...
in New York, was her partner. In July 1959 she received the promotion to Assistant Professor in charge. She published many articles, mostly in Italian Journals. Furthermore, Luisa Massimo spent a short time in the Kinderspital Zürich, where she collaborated with Walter Hitzig testing new drugs such as
azathioprine Azathioprine (AZA), sold under the brand name Imuran, among others, is an immunosuppressive medication. It is used in rheumatoid arthritis, granulomatosis with polyangiitis, Crohn's disease, ulcerative colitis, and systemic lupus erythematosus, ...
(an
immunosuppressant Immunosuppressive drugs, also known as immunosuppressive agents, immunosuppressants and antirejection medications, are drugs that inhibit or prevent activity of the immune system. Classification Immunosuppressive drugs can be classified in ...
) whose results were published in the leading hematological journal
Blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood in the c ...
. Such research is considered a milestone in the study of
transplants Transplant or Transplantation may refer to: Sciences *Transplanting a plant from one location to another *Organ transplantation, moving an organ from one body to another *Transplant thought experiment, an experiment similar to Trolley problem *Tra ...
, mostly of
kidney The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood ...
. She worked as well with Nasrollah Shaidi, a researcher of the
University of Wisconsin A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, t ...
, in the field of severe bone marrow aplasia. In spring 1960 she attended in
Basel , french: link=no, Bâlois(e), it, Basilese , neighboring_municipalities= Allschwil (BL), Hégenheim (FR-68), Binningen (BL), Birsfelden (BL), Bottmingen (BL), Huningue (FR-68), Münchenstein (BL), Muttenz (BL), Reinach (BL), Riehen (BS ...
the first International theoretical and practical course in
cytogenetics Cytogenetics is essentially a branch of genetics, but is also a part of cell biology/cytology (a subdivision of human anatomy), that is concerned with how the chromosomes relate to cell behaviour, particularly to their behaviour during mitosis an ...
, funded by the Ministry of Health. Back in Gaslini in 1962, she managed to organize a new Laboratory of cytogenetics. In April of the same year she became Professor of Pediatrics after a three days examination at the University of Rome. In 1966 the entrepreneur Dr. Vittorio Rollero and his wife Gianna, because of their 6 years old daughter admitted for leukemia, understood the financial difficulties of the Department, mostly for the heavy costs of drugs. They created the “Children’s Cancer and Leukemia Fund” to help and increase the tight budget. In 1972 a big amount of money allowed the birth of a new division named “Medicine 4th”. Since 1959 the relationship with
Odile Schweisguth Odile Schweisguth (1913-2002) was a French physician who is considered the pioneer of pediatric oncology in Europe and was the founder of the first child cancer department at the Institut Gustave Roussy (IGR) in Villejuif. Life and work Schweis ...
was a continuous help. Luisa Massimo and Renée Maurus of Brussels urged her for the creation of a Society of pediatric oncology. SIOP was founded in Paris in 1968.See the historical section of SIO
official website
/ref> The first congress of the
International Society of Paediatric Oncology The International Society of Pediatric Oncology (SIOP) () is a medical association for pediatric oncologists that is dedicated to increasing knowledge about childhood cancer. Its first president was Odile Schweisguth of France. It is an organisa ...
was held in 1969 in Madrid. Luisa Massimo organized the Sixth Congress (1974) in
Santa Margherita Ligure Santa Margherita Ligure ( lij, Santa Margaita) is a ''comune'' (municipality) in the Metropolitan City of Genoa in the Italian region Liguria, located about southeast of Genoa, in the area traditionally known as Tigullio. It has a port, used for b ...
together with the 4th Congress of the European Society of Pediatric Hematology and Immunology – ESPHI, and the foundation of the Italian Society of Pediatric Heamatology and Oncology. Since those years, considering also her knowledge of several languages she was invited to teach or to give seminars in several universities in Europe and other continents (Spain, Germany, Nigeria, Brasil, Mexico, Iceland, Argentina, Bolivia, Colombia, India, Japan, Australia, China, Ecuador, Jamaica).


Awards and prizes

* 1971: award for Oncology conferred by the
Italian Ministry of Education The Ministry of Education, University and Research (in it, Ministero dell'Istruzione, dell'Università e della Ricerca, italic=no or MIUR) is the ministry of the Italian government for the national education system, the Italian universities and ...
(Accademia Nazionale dei Lincei, Rome 18 June 1971) * 1991: the "American Italian Cancer Foundation's Prize for Scientific Excellence in Medicine" in New York * 2004: Golden Medal of Italian Republic for merit of
public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ...
(Rome, Quirinale), * 2011: Golden Medal “Master of Pediatrics" by the Italian Society of Pediatrics


Bibliography

* Luisa Massimo, ''Dentro la nostra vita. Ricordi di una pediatra oncologa'', Terra Ferma, Genova 2008, pp. 210 * Antonio Infante, Luca Borghi (eds.), ''Ai bambini e ai fiori, lo splendore del sole. Il ruolo dell'Istituto Gaslini nella storia della pediatria'', Rizzoli, Milano 2015, pp. 219–233 and 463-464 *
Italo Farnetani Italo may refer to: *Italo-, a prefix indicating a relation to Italy or Italians Film * ''Italo'' (film), a 2014 comedy film *Italo crime, a genre of crime film Music genres *Italo disco *Italo dance *Italo house People *Italo Allodi (1928–1 ...
, ''I venticinque pediatri, decorati con la Medaglia d'oro della sanità, hanno scritto la storia della Repubblica'', prefazione del ministro della salute
Beatrice Lorenzin Beatrice Lorenzin (born 14 October 1971) is an Italian politician belonging to the Democratic Party (Italy), Democratic Party, former leader of Popular Alternative, and former Italian Minister of Health, Minister of Health from 28 April 2013 to ...
, «Pediatria Preventiva & Sociale» 2016; 11 (3), pp 10–21- https://www.sipps.it/pdf/rivista/2016_03.pdf


Notes

{{DEFAULTSORT:Massimo, Luisa 1928 births 2016 deaths Italian pediatricians Italian oncologists Physicians from Genoa