Lucius Calpurnius Piso Frugi may refer to:
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Lucius Calpurnius Piso Frugi (consul 133 BC), Roman annalist and politician
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Lucius Calpurnius Piso Frugi Licinianus, adopted heir of the emperor Galba, murdered by the emperor Otho
{{hndis, Calpurnius Piso Frugi, Lucius