Louis Rapkine (July 14, 1904 – December 13, 1948) was a French
biologist
A biologist is a scientist who conducts research in biology. Biologists are interested in studying life on Earth, whether it is an individual Cell (biology), cell, a multicellular organism, or a Community (ecology), community of Biological inter ...
, specializing in
embryology
Embryology (from Greek ἔμβρυον, ''embryon'', "the unborn, embryo"; and -λογία, '' -logia'') is the branch of animal biology that studies the prenatal development of gametes (sex cells), fertilization, and development of embryos and ...
and
enzymology
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
. He is best known for his role in saving numerous French scientists from persecution during
World War II
World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...
, and in rebuilding the French scientific community and its institutions after the war.
[
]
Biography
Early life and family
Rapkine was born in the town of Tikhinichi ( be, Ціхінічы) in Belarus
Belarus,, , ; alternatively and formerly known as Byelorussia (from Russian ). officially the Republic of Belarus,; rus, Республика Беларусь, Respublika Belarus. is a landlocked country in Eastern Europe. It is bordered by R ...
, then part of the Russian Empire
The Russian Empire was an empire and the final period of the Russian monarchy from 1721 to 1917, ruling across large parts of Eurasia. It succeeded the Tsardom of Russia following the Treaty of Nystad, which ended the Great Northern War. ...
. As a result of anti-Jewish activity including the Kiev pogrom of 1905, his parents Israël Rapkine and Ida Sorkine moved to Paris in 1911. The family moved again in 1913 to Montréal
Montreal ( ; officially Montréal, ) is the second-most populous city in Canada and most populous city in the Canadian province of Quebec. Founded in 1642 as '' Ville-Marie'', or "City of Mary", it is named after Mount Royal, the triple-p ...
, where Rapkine studied medicine
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care pract ...
at McGill University
McGill University (french: link=no, Université McGill) is an English-language public research university located in Montreal, Quebec, Canada. Founded in 1821 by royal charter granted by King George IV,Frost, Stanley Brice. ''McGill Universit ...
from 1921 to 1924. He returned to Paris in 1924.
Rapkine married Sarah Malamud in New York in 1929, and their daughter Claude was born in Paris in 1932.[
]
Career
Rapkine became a researcher in Paris and at Cambridge
Cambridge ( ) is a university city and the county town in Cambridgeshire, England. It is located on the River Cam approximately north of London. As of the 2021 United Kingdom census, the population of Cambridge was 145,700. Cambridge bec ...
. He pursued biochemical research on the metabolic and developmental roles of sulfhydryl compounds, working initially with Charles Pérez and Maurice Caullery
Maurice Jules Gaston Corneille Caullery (5 September 1868, Bergues – 13 July 1958, Paris) was a French biologist.
Biography
He was born in Bergues in north France on 5 September 1868. His early education was in Douai.
He began as a lectu ...
at the Roscoff Maritime Station in 1925.[ He then worked at the ]Collège de France
The Collège de France (), formerly known as the ''Collège Royal'' or as the ''Collège impérial'' founded in 1530 by François I, is a higher education and research establishment (''grand établissement'') in France. It is located in Paris ne ...
under Emmanuel Fauré-Fremiet in 1926.[
In 1927, working under René Wurmser,][ Rapkine began a long research career at the in Paris, where he served as deputy head of the biophysics department from 1936 to 1940.][ He published a seminal paper in this area with Serbian biochemist Pavle Trpinac in 1939.][
As a foreigner in France in 1936, Rapkine was prohibited from engaging in political activity.][ According to the Collège de France:
Rapkine, who was 35 at the outbreak of ]World War II
World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...
, suspended his research career to devote himself to the French war effort until the end of hostilities.[ The French government sent Rapkine to London in January 1940, on an official mission to secure a supply of coal for French industrial and military purposes.][ While in England, he assisted ]James Crowther James Gerald Crowther (26 September 1899, Halifax, West Yorkshire, Halifax – 30 March 1983) was one of the founders of science journalism. He was appointed the scientific correspondent of ''The Manchester Guardian'' in 1928.
James was the second ...
in creating an Anglo-French Society of Sciences to formalize scientific cooperation between the two countries. In June 1940, after France's surrender to Germany, Rapkine advocated for the Society to help French scientists find refuge in the United Kingdom, but the Society dissolved when hostilities between France and England foreclosed scientific cooperation. Rapkine and Henri Laugier
Henri Laugier (1888-1973) was a French scholar. He served as the president of the French National Centre for Scientific Research from 1939 to 1940 and from 1943 to 1944.
Early life
Henri Laugier was born on 15 August 1888. He studied medicine, but ...
left London to continue their efforts in the United States.[
In New York from 1940 to 1944, Rapkine and Laugier organized the rescue of French scientists and those of other nationalities fleeing occupied France for the United States and Great Britain, with assistance from the ]Rockefeller Foundation
The Rockefeller Foundation is an American private foundation and philanthropic medical research and arts funding organization based at 420 Fifth Avenue, New York City. The second-oldest major philanthropic institution in America, after the Carneg ...
and the government-in-exile
A government in exile (abbreviated as GiE) is a political group that claims to be a country or semi-sovereign state's legitimate government, but is unable to exercise legal power and instead resides in a foreign country. Governments in exile u ...
of Free France
Free France (french: France Libre) was a political entity that claimed to be the legitimate government of France following the dissolution of the Third Republic. Led by French general , Free France was established as a government-in-exile ...
.[ In 1940 alone, Rapkine's organization assisted 35 scientists in secretly emigrating from France. Rapkine was officially named the head of the New York ''Bureau Scientifique de la France Libre'' (Free France scientific bureau) in December 1941.][
Rapkine also continued to seek a haven in London for refugee scientists. In 1943, Rapkine assisted Crowther in founding the Society for Visiting Scientists (SVS). Under its auspices as France's representative, Rapkine again undertook to gather exiled French scientists in England. As early as October 1943, the project had obtained a formal agreement from the Provisional French Government, but travel had become impossible. Rapkine complained directly to General ]Charles de Gaulle
Charles André Joseph Marie de Gaulle (; ; (commonly abbreviated as CDG) 22 November 18909 November 1970) was a French army officer and statesman who led Free France against Nazi Germany in World War II and chaired the Provisional Government ...
about the delays, noting that some of the exiled French scientists had already resigned their positions, and suggesting that travel restrictions could be lifted if the scientists were invited as scientific counselors of the French Army.[
After the ]liberation of Paris
The liberation of Paris (french: Libération de Paris) was a military battle that took place during World War II from 19 August 1944 until the German garrison surrendered the French capital on 25 August 1944. Paris had been occupied by Nazi Germ ...
at the end of August 1944, Rapkine was sent to London to establish a French scientific mission there, joined later by Frédéric Joliot-Curie
Jean Frédéric Joliot-Curie (; ; 19 March 1900 – 14 August 1958) was a French physicist and husband of Irène Joliot-Curie, with whom he was jointly awarded the Nobel Prize in Chemistry in 1935 for their discovery of Induced radioactivity. T ...
. Through October 1945, the London mission hosted scientists returning from America, as well as those who had been isolated in France during the German occupation.[
Rapkine returned to Paris, where he resumed his scientific work as the founding department head of a new department of cellular chemistry at the ]Pasteur Institute
The Pasteur Institute (french: Institut Pasteur) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vaccines f ...
, where he continued his research from 1946 until his death in 1948.[ During this period, he also was instrumental in securing American funds for exiled scientists to return to France or the United Kingdom, and for the reestablishment of French scientific facilities, including securing funding from the Rockefeller Foundation to reestablish the French ]National Center for Scientific Research
The French National Centre for Scientific Research (french: link=no, Centre national de la recherche scientifique, CNRS) is the French state research organisation and is the largest fundamental science agency in Europe.
In 2016, it employed 31,637 ...
(CNRS) led by Fréderic Joliot-Curie.[
]
Legacy
Louis Rapkine died in Paris from cancer in 1948. He has been honored for his intellectual and moral impact on scientists, including the young Jacques Monod
Jacques Lucien Monod (February 9, 1910 – May 31, 1976) was a French biochemist who won the Nobel Prize in Physiology or Medicine in 1965, sharing it with François Jacob and André Lwoff "for their discoveries concerning genetic control of en ...
.[
The Rapkine French Scientist Fund, overseen by ]Bethsabée de Rothschild
Baroness Bethsabée de Rothschild (assumed the name Batsheva after she immigrated to Israel in 1951; 23 September 1914 – 20 April 1999) was a philanthropist, dance patron, and member of the Rothschild banking family.
Early life and education
...
, was established in New York in 1951 to provide support and purchase materials for French scientists.[ Renamed the Pasteur Foundation in 1985, the fund became the U.S. affiliate of the ]Pasteur Institute
The Pasteur Institute (french: Institut Pasteur) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vaccines f ...
.[
In April 2019, a conference on Louis Rapkine was presented in Paris at the Institute of Physical and Chemical Biology, in celebration of the 80th anniversary of CRNS.][ Rapkine's service to his peers, starting in 1936 and including his role in saving an elite corps of French scientists from wartime persecution, was retraced using the Institute's unpublished archives.][
]
Awards
* Prix Pourat, Académie des Sciences
The French Academy of Sciences (French: ''Académie des sciences'') is a learned society, founded in 1666 by Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French scientific research. It was at the ...
(1932)
* Legion of Honour
The National Order of the Legion of Honour (french: Ordre national de la Légion d'honneur), formerly the Royal Order of the Legion of Honour ('), is the highest French order of merit, both military and civil. Established in 1802 by Napoleon, ...
(''Chevalier'', 1947)
Selected publications
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*
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*
*
References
{{DEFAULTSORT:Rapkine, Louis
Russian biologists
French biologists
McGill University Faculty of Medicine alumni
1904 births
1948 deaths
Belarusian Jews
People from Rahachow District
20th-century biologists
Emigrants from the Russian Empire to France