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Louis Agassiz Shaw Jr. (September 25, 1886 – August 27, 1940) was an instructor of
physiology Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical ...
at the School of Public Health of
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
, where he is credited in 1928 along with
Philip Drinker Philip Drinker (December 12, 1894 – October 19, 1972) was an industrial hygienist. With Louis Agassiz Shaw, he invented the first widely used iron lung in 1928. Family and early life Drinker's father was railroad man and Lehigh University ...
for inventing the Drinker respirator, the first widely used
iron lung An iron lung is a type of negative pressure ventilator (NPV), a mechanical respirator which encloses most of a person's body, and varies the air pressure in the enclosed space, to stimulate breathing.Shneerson, Dr. John M., Newmarket General ...
.


Family and early life

Shaw's parents were Louis Agassiz Shaw Sr. and Mary Elizabeth Saltonstall. Both parents came from wealthy and politically influential
Boston Brahmin The Boston Brahmins or Boston elite are members of Boston's traditional upper class. They are often associated with Harvard University; Anglicanism; and traditional Anglo-American customs and clothing. Descendants of the earliest English colonis ...
families with roots extending back to the ''
Mayflower ''Mayflower'' was an English ship that transported a group of English families, known today as the Pilgrims, from England to the New World in 1620. After a grueling 10 weeks at sea, ''Mayflower'', with 102 passengers and a crew of about 30, r ...
''. The couple's elder son was Quincy Adams Shaw III (born May 21, 1885). Louis Sr. died at home in Chestnut Hill from
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
when Louis Jr. was only four years old on July 2, 1891. Shaw's father was born at 26 Mount Vernon Street in Beacon Hill in 1861, and the following year the family moved to
Jamaica Plain Jamaica Plain is a neighborhood of in the City of Boston, Massachusetts, United States. Settled by Puritans seeking farmland to the south, it was originally part of the former Town of Roxbury, now also a part of the City of Boston. The commun ...
. He attended George Washington Copp Noble School in
Boston Boston (), officially the City of Boston, is the state capital and most populous city of the Commonwealth of Massachusetts, as well as the cultural and financial center of the New England region of the United States. It is the 24th- mo ...
, and graduated from Harvard University in 1884. He married Mary Elizabeth Saltonstall on June 30, 1884, in
Newton Newton most commonly refers to: * Isaac Newton (1642–1726/1727), English scientist * Newton (unit), SI unit of force named after Isaac Newton Newton may also refer to: Arts and entertainment * ''Newton'' (film), a 2017 Indian film * Newton ( ...
, right after the graduation ceremony. Shaw's uncle
Robert Gould Shaw II Robert Gould Shaw II (sometimes referred to as RGS II) (June 16, 1872 – March 29, 1930) was a wealthy landowner, international polo player of the Myopia Hunt Club and socialite of the leisure class in the greater Boston area of Massachusetts. He ...
was the first husband of Nancy Witcher Langhorne. She later married
Waldorf Astor Waldorf Astor, 2nd Viscount Astor, DL (19 May 1879 – 30 September 1952) was an American-born English politician and newspaper proprietor. He was a member of the Astor family. He was active in minor political roles. He was devoted to charitab ...
, the eldest son of
William Waldorf Astor William Waldorf "Willy" Astor, 1st Viscount Astor (31 March 1848 – 18 October 1919) was an American-British attorney, politician, businessman (hotels and newspapers), and philanthropist. Astor was a scion of the very wealthy Astor family of ...
and Mary Dahlgren Paul of the
Astor family The Astor family achieved prominence in business, society, and politics in the United States and the United Kingdom during the 19th and 20th centuries. With ancestral roots in the Italian Alps region of Italy by way of Germany, the Astors settle ...
. Shaw's paternal grandparents were
Quincy Adams Shaw Quincy Adams Shaw (February 8, 1825June 12, 1908) was a Boston Brahmin investor and business magnate who was the first president of Calumet and Hecla Mining Company. Family and early life Shaw came from a famous and moneyed Boston family. With ...
(one of the richest men in
Massachusetts Massachusetts (Massachusett language, Massachusett: ''Muhsachuweesut assachusett writing systems, məhswatʃəwiːsət'' English: , ), officially the Commonwealth of Massachusetts, is the most populous U.S. state, state in the New England ...
through his investment in the
Calumet and Hecla Mining Company The Calumet and Hecla Mining Company was a major copper-mining company based within Michigan's Copper Country. In the 19th century, the company paid out more than $72 million in shareholder dividends, more than any other mining company in the Uni ...
) and Pauline Agassiz. Shaw's great grandfather, for whom he was named, was
Louis Agassiz Jean Louis Rodolphe Agassiz ( ; ) FRS (For) FRSE (May 28, 1807 – December 14, 1873) was a Swiss-born American biologist and geologist who is recognized as a scholar of Earth's natural history. Spending his early life in Switzerland, he rec ...
, noted professor of
zoology Zoology ()The pronunciation of zoology as is usually regarded as nonstandard, though it is not uncommon. is the branch of biology that studies the Animal, animal kingdom, including the anatomy, structure, embryology, evolution, Biological clas ...
at Harvard University. Another of Shaw's great grandfathers was
Leverett Saltonstall I Leverett Saltonstall (June 13, 1783 – May 8, 1845), was a member of the United States House of Representatives from Massachusetts who also served as Speaker of the Massachusetts House of Representatives, President of the Massachusetts Senate, ...
, a member of the
United States House of Representatives The United States House of Representatives, often referred to as the House of Representatives, the U.S. House, or simply the House, is the Lower house, lower chamber of the United States Congress, with the United States Senate, Senate being ...
. Shaw married Joanne Bird of East Walpole on June 14, 1910. The couple had two children, Joanne Bird Shaw (born March 31, 1911) and Pauline Agassiz Shaw (November 4, 1915 — October 30, 1992).


Education

Louis Jr. followed his father's educational footsteps, first attending the George Washington Copp Noble School (which had been renamed the
Noble and Greenough School The Noble and Greenough School, commonly known as Nobles, is a coeducational, nonsectarian day and five-day boarding school for students in grades seven through twelve. It is near Boston on a campus that borders the Charles River in Dedham, Massa ...
in 1892) and later attending Harvard University, graduating in 1909. Shaw's cousin
Leverett Saltonstall Leverett A. Saltonstall (September 1, 1892June 17, 1979) was an American lawyer and politician from Massachusetts. He served three two-year terms as the List of Governors of Massachusetts, 55th Governor of Massachusetts, and for more than twent ...
also pursued the same academic path. Shaw continued to study for a couple of years after graduation, taking classes in
botany Botany, also called , plant biology or phytology, is the science of plant life and a branch of biology. A botanist, plant scientist or phytologist is a scientist who specialises in this field. The term "botany" comes from the Ancient Greek w ...
,
geology Geology () is a branch of natural science concerned with Earth and other astronomical objects, the features or rocks of which it is composed, and the processes by which they change over time. Modern geology significantly overlaps all other Ear ...
, and zoology. He contracted tuberculosis in the summer of 1911, and was consequently unable to work until the spring of 1913.


Career

Beginning in 1914, his research focused exclusively on physiology. Shaw and his family moved into the
brownstone Brownstone is a brown Triassic–Jurassic sandstone that was historically a popular building material. The term is also used in the United States and Canada to refer to a townhouse clad in this or any other aesthetically similar material. Type ...
building located at 6 Marlborough Street in the
Back Bay Back Bay is an officially recognized neighborhood of Boston, Massachusetts, built on reclaimed land in the Charles River basin. Construction began in 1859, as the demand for luxury housing exceeded the availability in the city at the time, and t ...
in 1917, having acquired the property upon the death of his grandmother, Pauline Agassiz Shaw. The building had a long history, having served as a private day school (18851893), later as headquarters of the
Massachusetts Woman Suffrage Association The Massachusetts Woman Suffrage Association (MWSA) was an American organization devoted to women's suffrage in Massachusetts. It was active from 1870 to 1919. History The MWSA was founded in 1870 by suffrage activists Julia Ward Howe, Lucy Stone, ...
(19041915), and then as headquarters of the Women's Municipal League of Boston (19151917).Boston Architecture: 6 Marlborough Street
/ref> From late 1917 until early 1919, Shaw and his research team conducted investigations in his home laboratory on the physiological effects of poisonous gases and other problems related to the ongoing war in Europe. In the spring of 1919, he joined the faculty at the Harvard-MIT School for Health Officers in the department of
industrial hygiene Occupational hygiene (United States: industrial hygiene (IH)) is the anticipation, recognition, evaluation, control, and confirmation (ARECC) of protection from hazards at work that may result in injury, illness, or affect the well being of work ...
. The Harvard-MIT School for Health Officers was a joint venture between
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
and
Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a private land-grant research university in Cambridge, Massachusetts. Established in 1861, MIT has played a key role in the development of modern technology and science, and is one of the ...
(MIT) that began in 1913. The joint venture ended in 1922, when the
Harvard School of Public Health The Harvard T.H. Chan School of Public Health is the public health school of Harvard University, located in the Longwood Medical Area of Boston, Massachusetts. The school grew out of the Harvard-MIT School for Health Officers, the nation's first ...
was formally established. Shaw and his family continued to live at 6 Marlborough Street at least until 1927. Shaw was a member of the Tennis and Racquet Club, located on
Boylston Street Boylston Street is a major east–west thoroughfare in the city of Boston, Massachusetts. The street begins in Boston's Chinatown neighborhood, forms the southern border of the Boston Public Garden and Boston Common, runs through Back Bay, and e ...
not far from his house. In that year, Shaw was arrested for the
distillation Distillation, or classical distillation, is the process of separation process, separating the components or substances from a liquid mixture by using selective boiling and condensation, usually inside an apparatus known as a still. Dry distilla ...
of
alcohol Alcohol most commonly refers to: * Alcohol (chemistry), an organic compound in which a hydroxyl group is bound to a carbon atom * Alcohol (drug), an intoxicant found in alcoholic drinks Alcohol may also refer to: Chemicals * Ethanol, one of sev ...
, which was illegal in the United States during
Prohibition Prohibition is the act or practice of forbidding something by law; more particularly the term refers to the banning of the manufacture, storage (whether in barrels or in bottles), transportation, sale, possession, and consumption of alcoholic ...
, in effect from 1920 to 1933. Shortly after that event, the house was demolished and replaced by a five-story, 21-unit apartment house. Shaw was an instructor in physiology at the Harvard School of Public Health, where he is credited in 1928 along with Philip Drinker (1894–1972, associate professor of industrial hygiene) and his brother Cecil Kent Drinker (1887–1956, later
dean Dean may refer to: People * Dean (given name) * Dean (surname), a surname of Anglo-Saxon English origin * Dean (South Korean singer), a stage name for singer Kwon Hyuk * Dean Delannoit, a Belgian singer most known by the mononym Dean Titles * ...
of the Harvard School of Public Health) for inventing the first widely used iron lung. The machine was powered by an electric motor with air pumps from two vacuum cleaners. The air pumps changed the pressure inside a rectangular, airtight metal box, pulling air in and out of the lungs.


Publications

* * * * * * *


References

{{DEFAULTSORT:Shaw, Louis Agassiz Junior American inventors Harvard University staff 1886 births 1940 deaths
Louis Louis may refer to: * Louis (coin) * Louis (given name), origin and several individuals with this name * Louis (surname) * Louis (singer), Serbian singer * HMS ''Louis'', two ships of the Royal Navy See also Derived or associated terms * Lewis ( ...
American people of English descent American people of Swiss descent Harvard University alumni Noble and Greenough School alumni People from Jamaica Plain People from Beacon Hill, Boston