Loránd Kesztyűs ( Sarkad,

Hungary Hungary ( hu, Magyarország ) is a landlocked country in Central Europe. Spanning of the Carpathian Basin, it is bordered by Slovakia to the north, Ukraine to the northeast, Romania to the east and southeast, Serbia to the south, Croatia a ...

, 11 April 1915 −

Debrecen Debrecen ( , is Hungary's second-largest city, after Budapest, the regional centre of the Northern Great Plain region and the seat of Hajdú-Bihar County. A city with county rights, it was the largest Hungarian city in the 18th century and i ...

, Hungary, 17 August 1979) was a Hungarian

physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...

, immunologist, pathophysiologist, a full member of the

Hungarian Academy of Sciences The Hungarian Academy of Sciences ( hu, Magyar Tudományos Akadémia, MTA) is the most important and prestigious learned society of Hungary. Its seat is at the bank of the Danube in Budapest, between Széchenyi rakpart and Akadémia utca. Its ma ...

Career

He studied at the

University of Debrecen ThUniversity of Debrecen( hu, Debreceni Egyetem) is a university located in Debrecen, Hungary. It is the oldest continuously operating institution of higher education in Hungary ever since its establishment in 1538 by Suleiman the Magnificent f ...

until 1938, then worked at the Physiological and General Pathological Institute of the university. In 1948 he was appointed director of the Pathophysiological Institute of Debrecen, a post which he held until his death. During his directorship the institute became the research center of

immunology Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see there ...

in Hungary. Antibodies to muscle proteins were first prepared by Kesztyűs and his team; they also studied the reaction of these antibodies with the muscle protein antigens. During the early period of his career he studied - together with István Went -

antibodies An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the ...

and

flavins Flavins (from Latin ''flavus'', "yellow") are organic compounds, like their base, pteridine. They are formed by the tricyclic heterocycle isoalloxazine. The biochemical source is the vitamin riboflavin. The flavin moiety is often attached with ...

, on the ground of their researches they could successfully produce immunizer

pharmaceutical drug A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and re ...

s used as treatment for

allergies Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic derma ...

. Later he investigated the relationship between

nervous system In biology, the nervous system is the highly complex part of an animal that coordinates its actions and sensory information by transmitting signals to and from different parts of its body. The nervous system detects environmental changes th ...

and

immunity Immunity may refer to: Medicine * Immunity (medical), resistance of an organism to infection or disease * ''Immunity'' (journal), a scientific journal published by Cell Press Biology * Immune system Engineering * Radiofrequence immunity desc ...

, and stated that despite the

neurological Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal ...

understanding being in force at that time the nervous system doesn't impact either on production of antibodies, or on

anaphylaxis Anaphylaxis is a serious, potentially fatal allergic reaction and medical emergency that is rapid in onset and requires immediate medical attention regardless of use of emergency medication on site. It typically causes more than one of the follow ...

. He was a corresponding (1967), then a full member (1976) of the

, and the founder and first chairman of the Hungarian Immunological Society (1971).

Works

*''A kórélettan tankönyve.'' ectures on pathophysiology.Budapest, Medicina, 1963, 587 p. (With József Sós) *''Immunität und Nervensystem.'' Budapest, Akadémiai, 1967, 159 p. *''Kórélettan.'' athophysiology.Budapest, Medicina, 1975, 762 p.

References

*''A Magyar Tudományos Akadémia tagjai 1825–2002 II.'' embers of the Hungarian Academy of Sciences 1825–2002.Budapest, 2003, pp. 667. {{DEFAULTSORT:Kesztyus Lorand Hungarian immunologists Hungarian physiologists Members of the Hungarian Academy of Sciences 1979 deaths 1915 births