Locomotor Ataxia
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Locomotor
ataxia Ataxia is a neurological sign consisting of lack of voluntary coordination of muscle movements that can include gait abnormality, speech changes, and abnormalities in eye movements. Ataxia is a clinical manifestation indicating dysfunction of ...
is the inability to precisely control one's own bodily movements. __TOC__


Disease

People afflicted with this disease may walk in a jerky, non-fluid manner. They will not know where their arms and legs are without looking (i.e. a failure of
proprioception Proprioception ( ), also referred to as kinaesthesia (or kinesthesia), is the sense of self-movement, force, and body position. It is sometimes described as the "sixth sense". Proprioception is mediated by proprioceptors, mechanosensory neurons ...
), but can, for instance, feel and locate a hot object placed against their feet. It is often a symptom of
tabes dorsalis Tabes dorsalis is a late consequence of neurosyphilis, characterized by the slow degeneration (specifically, demyelination) of the neural tracts primarily in the dorsal root ganglia of the spinal cord (nerve root). These patients have lancinating n ...
, which is a key finding in tertiary
syphilis Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms of syphilis vary depending in which of the four stages it presents (primary, secondary, latent, an ...
. It is caused by degeneration of the posterior (dorsal) white column of the spinal cord.


In popular culture

The chilling effects of this condition and its connection to
venereal disease Sexually transmitted infections (STIs), also referred to as sexually transmitted diseases (STDs) and the older term venereal diseases, are infections that are spread by sexual activity, especially vaginal intercourse, anal sex, and oral se ...
are dramatized in the story "Love O' Women" by
Rudyard Kipling Joseph Rudyard Kipling ( ; 30 December 1865 – 18 January 1936)''The Times'', (London) 18 January 1936, p. 12. was an English novelist, short-story writer, poet, and journalist. He was born in British India, which inspired much of his work. ...
.
Bram Stoker Abraham Stoker (8 November 1847 – 20 April 1912) was an Irish author who is celebrated for his 1897 Gothic horror novel '' Dracula''. During his lifetime, he was better known as the personal assistant of actor Sir Henry Irving and busine ...
's
death certificate A death certificate is either a legal document issued by a medical practitioner which states when a person died, or a document issued by a government civil registration office, that declares the date, location and cause of a person's death, as ...
named the cause of death as "Locomotor Ataxia 6 months", presumed to be a reference to syphilis.


References

Neurodegenerative disorders {{nervoussystem-disease-stub