Livia S. Eberlin
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Livia Schiavinato Eberlin is a Brazilian
analytical chemist Analytical chemistry studies and uses instruments and methods to separate, identify, and quantify matter. In practice, separation, identification or quantification may constitute the entire analysis or be combined with another method. Separati ...
who won a MacArthur "Genius" Fellowship for her research on the use of mass spectrometry to detect cancerous tissue.


Education and career

Eberlin is the daughter of Marcos Nogueira Eberlin, a Brazilian chemist at the
University of Campinas The State University of Campinas ( pt, Universidade Estadual de Campinas), commonly called Unicamp, is a public research university in the state of São Paulo, Brazil. Unicamp is consistently ranked among the top universities in Brazil and ...
. She was born in
Campinas Campinas (, ''Plains'' or ''Meadows'') is a Brazilian municipality in São Paulo State, part of the country's Southeast Region. According to the 2020 estimate, the city's population is 1,213,792, making it the fourteenth most populous Brazilian ...
, and she earned her bachelor's degree in 2007 from the University of Campinas. During her undergraduate studies, she did summer research in mass spectrometry at
Purdue University Purdue University is a public land-grant research university in West Lafayette, Indiana, and the flagship campus of the Purdue University system. The university was founded in 1869 after Lafayette businessman John Purdue donated land and mone ...
, where her father also had research ties. She later enrolled at Purdue for her doctorate, which she completed in 2012. Her dissertation, ''Developments in ambient mass spectrometry imaging and its applications in biomedical research and cancer diagnosis'', was supervised by
R. Graham Cooks Robert Graham Cooks is the Henry Bohn Hass Distinguished Professor of Chemistry in the Aston Laboratories for Mass Spectrometry at Purdue University. He is an ISI Highly Cited Chemist, with over 1,000 publications and an H-index of 134. Educatio ...
. After postdoctoral research at Stanford University with
Richard Zare Richard Neil Zare (born November 19, 1939, in Cleveland, Ohio) is the Marguerite Blake Wilbur Professor in Natural Science and a Professor of Chemistry at Stanford University. Throughout his career, Zare has made a considerable impact in physical ...
, she joined the faculty at the
University of Texas at Austin The University of Texas at Austin (UT Austin, UT, or Texas) is a public research university in Austin, Texas. It was founded in 1883 and is the oldest institution in the University of Texas System. With 40,916 undergraduate students, 11,07 ...
in 2015 in the Department of Chemistry. She joined
Baylor College of Medicine Baylor College of Medicine (BCM) is a medical school and research center in Houston, Texas, within the Texas Medical Center, the world's largest medical center. BCM is composed of four academic components: the School of Medicine, the Graduate S ...
as Associate Professor in 2021.


Research

Eberlin developed a pen-like device, called the "MasSpec Pen" or "The Cancer Pen", that has demonstrated the capability to detect cancerous tissue by delivering a discrete water droplet to extract biomolecules from the tissue's surface and transporting them to a mass spectrometer for molecular analysis. The pen allows surgeons to achieve a better understanding of which tissues should be removed. As a co-principal investigator at the University of Texas at Austin, Eberlin has developed a method to detect thyroid cancer using
Desorption electrospray ionization Desorption electrospray ionization (DESI) is an ambient ionization technique that can be coupled to mass spectrometry (MS) for chemical analysis of samples at atmospheric conditions. Coupled ionization sources-MS systems are popular in chemical a ...
mass spectrometry (DESI-MS) imaging of fine-needle aspiration biopsies. It is two-thirds more accurate than the test already in use, fine-needle aspiration, which yields more indeterminate results when used in isolation. In addition to her work on cancer diagnosis, Eberlin has also worked with Cooks and her father on the use of mass spectrometry to quickly detect
counterfeit money Counterfeit money is currency produced without the legal sanction of a state or government, usually in a deliberate attempt to imitate that currency and so as to deceive its recipient. Producing or using counterfeit money is a form of fraud or fo ...
. Eberlin is concerned about the representation of women and diversity in science. In interviews, she has stressed the importance of women in higher levels of academia as well as leadership.


Awards and recognition

Eberlin was named among the Forbes "30 Under 30" list in 2015. She won the Marion Milligan Mason Award of the American Association for the Advancement of Science in 2016. The award is given every two years to promising young female researchers in chemistry. She won the MacArthur "Genius" Fellowship from the John D. and Catherine T. MacArthur Foundation in 2018 for her research on the use of mass spectrometry "to differentiate more quickly and accurately diseased from healthy tissues during surgery". She is the first UT Austin professor to win MacArthur grant this century. The award consists of a $625,000 no-strings-attached grant. According to the foundation, this award goes to "extraordinarily talented and creative individuals as an investment in their potential". She also won the Moore Inventor Fellowship in 2018. She received the 2020 Curt Brunnée Award from the
International Mass Spectrometry Foundation The International Mass Spectrometry Foundation (IMSF) is a non-profit scientific organization in the field of mass spectrometry. It operates the International Mass Spectrometry Society, which consists of 37 member societies and sponsors the Inter ...
. She was named on the Power List by the Analytical Scientist in 2014, 2018, 2019, 2021, 2022, and 2023. She received the 2024 Norman Hackerman Award from the Welch Foundation.


Selected publications


Research articles

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References


External links


Livia S. Eberlin Research Group
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MassSpec Pen
{{DEFAULTSORT:Eberlin, Livia S. Year of birth missing (living people) Living people 21st-century American chemists Brazilian chemists Brazilian women chemists State University of Campinas alumni Purdue University alumni University of Texas at Austin faculty MacArthur Fellows Mass spectrometrists