Litten's Sign
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Litten's sign is a
clinical sign Signs and symptoms are the observed or detectable signs, and experienced symptoms of an illness, injury, or condition. A sign for example may be a higher or lower temperature than normal, raised or lowered blood pressure or an abnormality showin ...
in which
cotton wool spots Cotton wool spots are opaque fluffy white patches on the retina of the eye that are considered an abnormal finding during a funduscopic exam (also called an ophthalmoscopic exam). Cotton wool spots are typically a sign of another disease state, mo ...
are seen on fundoscopic examination of the
retina The retina (from la, rete "net") is the innermost, light-sensitive layer of tissue of the eye of most vertebrates and some molluscs. The optics of the eye create a focused two-dimensional image of the visual world on the retina, which then ...
in patients with
infective endocarditis Infective endocarditis is an infection of the inner surface of the heart, usually the valves. Signs and symptoms may include fever, small areas of bleeding into the skin, heart murmur, feeling tired, and low red blood cell count. Complications ...
. The sign is named after
Moritz Litten Moritz Litten (August 10, 1845 – May 31, 1907) was a German physician who was a native of Berlin. He was a son-in-law to pathologist Ludwig Traube (1818–1876). Biography He studied medicine at the Universities of Heidelberg, Marburg and Ber ...
.


See also

*
Roth's spot Roth's spots, also known as Litten spots or the Litten sign, are non-specific red spots with white or pale centres, seen on the retina and although traditionally associated with infective endocarditis, can occur in a number of other conditions incl ...


References

Medical signs Cardiology {{med-sign-stub