List Of Progestogens
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This is a list of
progestogen Progestogens, also sometimes written progestagens or gestagens, are a class of natural or synthetic steroid hormones that bind to and activate the progesterone receptors (PR). Progesterone is the major and most important progestogen in the body. ...
s that are or that have been used in clinical or veterinary medicine. They are
steroid A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes that alter membrane fluidity; and a ...
s and include derivatives of
progesterone Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. It belongs to a group of steroid hormones called the progestogens and is the m ...
and testosterone.


Progesterone derivatives


Retroprogesterone derivatives

Note that although an active progestogen, retroprogesterone is not medically used.


17α-Hydroxyprogesterone derivatives

Note that 17α-hydroxyprogesterone is inactive as a progestogen and is not used medically. The 19-norprogesterone derivatives gestonorone caproate (gestronol hexanoate), nomegestrol acetate, segesterone acetate (nestorone, elcometrine), and
norgestomet Norgestomet, or norgestamet, sold under the brand name Syncro-Mate B and Crestar, is a progestin medication which is used in veterinary medicine to control estrus and ovulation in cattle. Uses Veterinary Norgestomet is used in veterinary medi ...
are also derivatives of 17α-hydroxyprogesterone (see
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).


17α-Methylprogesterone derivatives

Note that although an active progestogen, 17α-methylprogesterone is not medically used. The 19-norprogesterone derivatives
demegestone Demegestone, sold under the brand name Lutionex, is a progestin medication which was previously used to treat luteal insufficiency but is now no longer marketed.http://www.micromedexsolutions.com/micromedex2/ It is taken oral administration, by m ...
, promegestone, and trimegestone are also derivatives of 17α-methylprogesterone (see
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).


Other 17α-substituted progesterone derivatives


19-Norprogesterone derivatives

Note that although an active progestogen, 19-norprogesterone is not medically used.


Testosterone derivatives

Note that testosterone itself does not have significant progestogenic activity. Testosterone is instead classified as an anabolic-androgenic steroid and is included here purely because it is the parent structure of this group of progestins.


17α-Ethynyltestosterone derivatives


19-Nortestosterone derivatives

Note that while nandrolone (19-nortestosterone) does have significant progestogenic activity, it is not used as a progestogen. It is instead classified as an androgenic-anabolic steroid and is included here purely because it is an important parent structure of this group of progestins.


17α-Ethynyl-19-nortestosterone derivatives


Estranes


18-Methylestranes (13β-ethylgonanes)


Other 17α-substituted 19-nortestosterone derivatives


Spirolactone derivatives

Note that although an active progestogen, SC-5233 (spirolactone) is not medically used.


See also

*
List of steroids List of steroids may refer to: * List of androgens/anabolic steroids – steroidal androgens/anabolic steroids * List of androgens/anabolic steroids (alternate) – steroidal androgens/anabolic steroids * List of steroidal antiandrogens – st ...
* List of progestogen esters


Notes

? = Chemical names that are unverified.


Further reading

* {{Progesterone receptor modulators Progestogens Steroids Progestogens