Lipoprotein receptor-related proteins, low density lipoprotein receptor-related proteins (
HGNC
The HUGO Gene Nomenclature Committee (HGNC) is a committee of the Human Genome Organisation (HUGO) that sets the standards for human gene nomenclature. The HGNC approves a ''unique'' and ''meaningful'' name for every known human gene, based on a q ...
) or prolow-density lipoprotein receptor-related protein (
UniProt
UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from ...
), abbreviated LRP, are a group of
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
s.
They include:
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LRP1
Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster of differentiation 91 (CD91), is a protein forming a receptor found in the plasma membr ...
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LRP1B
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LRP2
Low density lipoprotein receptor-related protein 2 also known as LRP-2 or megalin is a protein which in humans is encoded by the ''LRP2'' gene.
Function
LRP2 was identified as the antigen of rat experimental membranous nephropathy (Heyman neph ...
(megalin)
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LRP3
Low density lipoprotein receptor-related protein 3 (LRP-3) is a protein that in humans is encoded by the ''LRP3'' gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of here ...
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LRP4
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LRP5
Low-density lipoprotein receptor-related protein 5 is a protein that in humans is encoded by the ''LRP5'' gene. LRP5 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway. Mutations in LRP5 can le ...
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LRP6
Low-density lipoprotein receptor-related protein 6 is a protein that in humans is encoded by the ''LRP6'' gene. LRP6 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway.
Structure
LRP6 is a t ...
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LRP8, apolipoprotein e receptor
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LRP10
Low-density lipoprotein receptor-related protein 10 is a protein that in humans is encoded by the ''LRP10'' gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." ...
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LRP11
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LRP12
Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster of differentiation 91 (CD91), is a protein forming a receptor found in the plasma membran ...
See also
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LRPAP1 (low density lipoprotein receptor-related protein associated protein 1)
Lipoprotein receptor-related proteins are co-receptors for Wnt signaling.
{{Lipoprotein metabolism
Human proteins
Lipoprotein receptor-related proteins are co-receptors for Wnt signaling.