Linear atrophoderma of Moulin (also known as "Moulin atrophoderma linearis"
) is an acquired unilateral
dermatitis
Dermatitis is inflammation of the skin, typically characterized by itchiness, redness and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened. The area of skin involved can v ...
localized along the
Blaschko lines. It affects
children
A child ( : children) is a human being between the stages of birth and puberty, or between the developmental period of infancy and puberty. The legal definition of ''child'' generally refers to a minor, otherwise known as a person younger ...
or
adolescents
Adolescence () is a transitional stage of physical and psychological development that generally occurs during the period from puberty to adulthood (typically corresponding to the age of majority). Adolescence is usually associated with the te ...
of both genders, involving the
trunk
Trunk may refer to:
Biology
* Trunk (anatomy), synonym for torso
* Trunk (botany), a tree's central superstructure
* Trunk of corpus callosum, in neuroanatomy
* Elephant trunk, the proboscis of an elephant
Computing
* Trunk (software), in rev ...
and the
limbs. It is, presumably, a rare
cutaneous
Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation.
Other animal coverings, such as the arthropod exoskeleton, have different de ...
form of
mosaicism
Mosaicism or genetic mosaicism is a condition in multicellular organisms in which a single organism possesses more than one genetic line as the result of genetic mutation. This means that various genetic lines resulted from a single fertilized e ...
.
This disease was first referred to as Atrophoderma of Moulin after Dr.Moulin who first reported it in 1992
then was renamed as linear atrophoderma of Moulin.
Only a few dozen cases have been described; for this reason, LAM is considered to be a very rare disorder.
See also
*
Atrophoderma of Pasini and Pierini
Morphea is a form of scleroderma that involves isolated patches of hardened skin on the face, hands, and feet, or anywhere else on the body, with no internal organ involvement.
Signs and symptoms
Morphea most often presents as macules or plaq ...
*
List of cutaneous conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against t ...
References
{{reflist
Connective tissue diseases