Lin Chao is a
Chinese Brazilian
Chinese Brazilians ( pt, Sino-brasileiro, italic=yes or ''Chinês-brasileiro''; zh, c=巴西華人 / 巴西华人 or 巴西華裔 / 巴西华裔) are Brazilians of Chinese ancestry or birth. The Chinese Brazilian population was estimated to be a ...
American
evolutionary biologist
Evolutionary biology is the subfield of biology that studies the evolutionary processes (natural selection, common descent, speciation) that produced the diversity of life on Earth. It is also defined as the study of the history of life for ...
and
geneticist
A geneticist is a biologist or physician who studies genetics, the science of genes, heredity, and variation of organisms. A geneticist can be employed as a scientist or a lecturer. Geneticists may perform general research on genetic processe ...
. Chao gained his
PhD PHD or PhD may refer to:
* Doctor of Philosophy (PhD), an academic qualification
Entertainment
* '' PhD: Phantasy Degree'', a Korean comic series
* ''Piled Higher and Deeper'', a web comic
* Ph.D. (band), a 1980s British group
** Ph.D. (Ph.D. albu ...
in 1977 from the
University of Massachusetts Amherst
The University of Massachusetts Amherst (UMass Amherst, UMass) is a public research university in Amherst, Massachusetts and the sole public land-grant university in Commonwealth of Massachusetts. Founded in 1863 as an agricultural college, it ...
, as a student of Bruce R. Levin (now at
Emory University
Emory University is a private research university in Atlanta, Georgia. Founded in 1836 as "Emory College" by the Methodist Episcopal Church and named in honor of Methodist bishop John Emory, Emory is the second-oldest private institution of ...
), and was a
NIH
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
postdoctoral fellow at
Princeton University
Princeton University is a private university, private research university in Princeton, New Jersey. Founded in 1746 in Elizabeth, New Jersey, Elizabeth as the College of New Jersey, Princeton is the List of Colonial Colleges, fourth-oldest ins ...
in the laboratory of Edward C. Cox. He spent most of his career in the Department of Biology of the
University of Maryland, College Park
The University of Maryland, College Park (University of Maryland, UMD, or simply Maryland) is a public land-grant research university in College Park, Maryland. Founded in 1856, UMD is the flagship institution of the University System of Mary ...
and is currently at the
Ecology
Ecology () is the study of the relationships between living organisms, including humans, and their physical environment. Ecology considers organisms at the individual, population, community, ecosystem, and biosphere level. Ecology overlaps wi ...
, Behavior and Evolution Section of the
University of California, San Diego
The University of California, San Diego (UC San Diego or colloquially, UCSD) is a public university, public Land-grant university, land-grant research university in San Diego, California. Established in 1960 near the pre-existing Scripps Insti ...
.
Chao is best known for his early work on the evolution of
bacteriocins
Bacteriocins are proteinaceous or peptide, peptidic toxins produced by bacteria to inhibit the growth of similar or closely related bacterial strain(s). They are similar to yeast and paramecium killing factors, and are structurally, functionally ...
, his demonstration of
Muller’s ratchet in the
RNA Virus
An RNA virus is a virusother than a retrovirusthat has ribonucleic acid (RNA) as its genetic material. The nucleic acid is usually single-stranded RNA ( ssRNA) but it may be double-stranded (dsRNA). Notable human diseases caused by RNA viruses ...
Phi-6 and his work on sex in viruses. More recently, he was instrumental in the demonstration of the evolution of parasitic genetic elements in co-infecting
bacteriophages
A bacteriophage (), also known informally as a ''phage'' (), is a duplodnaviria virus that infects and replicates within bacteria and archaea. The term was derived from "bacteria" and the Greek φαγεῖν ('), meaning "to devour". Bacterio ...
and experimental tests of
Fisher's geometric model Fisher's geometric model (FGM) is an evolutionary model of the effect sizes and effect on fitness (biology), fitness of spontaneous mutations proposed by Ronald Fisher to explain the distribution of effects of mutations that could contribute to adap ...
. He argued that "
life
Life is a quality that distinguishes matter that has biological processes, such as signaling and self-sustaining processes, from that which does not, and is defined by the capacity for growth, reaction to stimuli, metabolism, energ ...
is
evolution
Evolution is change in the heritable characteristics of biological populations over successive generations. These characteristics are the expressions of genes, which are passed on from parent to offspring during reproduction. Variation ...
by
natural selection
Natural selection is the differential survival and reproduction of individuals due to differences in phenotype. It is a key mechanism of evolution, the change in the heritable traits characteristic of a population over generations. Charle ...
". The approach generally used in his laboratory is called microbial
experimental evolution
Experimental evolution is the use of laboratory experiments or controlled field manipulations to explore evolutionary dynamics. Evolution may be observed in the laboratory as individuals/populations adapt to new environmental conditions by natura ...
.
Chao is married to
Camilla Rang
Camilla may refer to:
People
* Camilla (given name), including a list of people with the name
** Camilla, Queen Consort (born 1947), wife of King Charles III
Places
* Camilla, Georgia, a city in the United States
* Camilla Castle, an alternativ ...
, a fellow scientist, T-shirt designer and Swedish children's book author.
* UCSD Chancellor's Associates Faculty Excellence Award (2014)
References
External links
Chao's Faculty Webpage at UCSD
American people of Brazilian descent
American people of Chinese descent
Brazilian people of Chinese descent
Phage workers
University of California, San Diego faculty
Living people
University of Massachusetts Amherst alumni
Princeton University fellows
Year of birth missing (living people)
Brazilian American
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