Lewis Hastings Sarett
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Lewis Hastings Sarett (December 22, 1917 – November 29, 1999) was an American organic chemist. While serving as a research scientist at Merck & Co., Inc., synthesized
cortisone Cortisone is a pregnene (21-carbon) steroid hormone. It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug; it is not synthesized in the adrenal glands. Cortisol is converted by the action of the enzy ...
.


Biography

He was born in
Champaign, Illinois Champaign ( ) is a city in Champaign County, Illinois, United States. The population was 88,302 at the 2020 census. It is the tenth-most populous municipality in Illinois and the fourth most populous city in Illinois outside the Chicago metropo ...
. His father was Lew Sarett, a renowned Jewish poet and professor and an uncle of former Secretary of Defense
Donald Rumsfeld Donald Henry Rumsfeld (July 9, 1932 – June 29, 2021) was an American politician, government official and businessman who served as Secretary of Defense from 1975 to 1977 under president Gerald Ford, and again from 2001 to 2006 under Presi ...
. He lived in
Laona, Wisconsin Laona is a town in Forest County, Wisconsin, United States. The population was 1,212 at the 2010 census. The census-designated place of Laona is located in the town. The unincorporated community of Blackwell Junction is also located partially ...
for a time and then attended high school in
Highland Park, Illinois Highland Park is a suburban city located in the southeastern part of Lake County, Illinois, United States, about north of downtown Chicago. Per the 2020 census, the population was 30,176. Highland Park is one of several municipalities located o ...
. He received a
Bachelor of Science A Bachelor of Science (BS, BSc, SB, or ScB; from the Latin ') is a bachelor's degree awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University of ...
from
Northwestern University Northwestern University is a private research university in Evanston, Illinois. Founded in 1851, Northwestern is the oldest chartered university in Illinois and is ranked among the most prestigious academic institutions in the world. Charte ...
in 1939 (
Phi Beta Kappa The Phi Beta Kappa Society () is the oldest academic honor society in the United States, and the most prestigious, due in part to its long history and academic selectivity. Phi Beta Kappa aims to promote and advocate excellence in the liberal a ...
) and his
doctorate A doctorate (from Latin ''docere'', "to teach"), doctor's degree (from Latin ''doctor'', "teacher"), or doctoral degree is an academic degree awarded by universities and some other educational institutions, derived from the ancient formalism ''l ...
from
Princeton University Princeton University is a private university, private research university in Princeton, New Jersey. Founded in 1746 in Elizabeth, New Jersey, Elizabeth as the College of New Jersey, Princeton is the List of Colonial Colleges, fourth-oldest ins ...
. He worked for Merck & Co. for 38 years retiring in 1982. He invented a Process of Treating Pregnene Compounds
Cortisone Cortisone is a pregnene (21-carbon) steroid hormone. It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug; it is not synthesized in the adrenal glands. Cortisol is converted by the action of the enzy ...
, Patent Number 2,462,133. Named after him is the
Sarett Oxidation The Sarett oxidation is an organic reaction that oxidizes primary and secondary alcohols to aldehydes and ketones, respectively, using chromium trioxide and pyridine. Unlike the similar Jones oxidation, the Sarett oxidation will not further oxidiz ...
which is the oxidation of an alcohol to a ketone or an aldehyde using chromic oxide and pyridine. Primary alcohols will be oxidised to aldehydes and not carboxylic acids.


Writing career

He is also famous for writing the poem The Four Little Foxes to raise awareness about animal rights.


Honors and awards

*1964
Scheele Award The Scheele Award () is a scientific award given by the Swedish , an organisation mainly consisting of pharmacists. The award is given to commemorate the pharmacist and chemist Carl Wilhelm Scheele (1742–1786) and has been appointed since 1961, i ...
*1972
Chemical Pioneer Award The Chemical Pioneer Award, established in 1966, is awarded by the American Institute of Chemists to recognize chemists or chemical engineers who have made outstanding contributions to advances in chemistry or the chemical profession. Recent rec ...
from the
American Institute of Chemists The American Institute of Chemists (AIC) is an organization founded in 1923 with the goal of advancing the chemistry profession in the United States. The institute is known for its yearly awards recognizing contributions of individuals in this fie ...
*1975
National Medal of Science The National Medal of Science is an honor bestowed by the President of the United States to individuals in science and engineering who have made important contributions to the advancement of knowledge in the fields of behavioral and social scienc ...
*1976
Perkin Medal The Perkin Medal is an award given annually by the Society of Chemical Industry (American Section) to a scientist residing in America for an "innovation in applied chemistry resulting in outstanding commercial development." It is considered the h ...
*1980 Inducted into the
National Inventors Hall of Fame The National Inventors Hall of Fame (NIHF) is an American not-for-profit organization, founded in 1973, which recognizes individual engineers and inventors who hold a U.S. patent of significant technology. Besides the Hall of Fame, it also opera ...
*1980 Awarded the
IRI Medal The IRI Medal, established by the Industrial Research Institute (IRI) in 1946, recognizes and honors leaders of technology for their outstanding accomplishments in technological innovation which contribute broadly to the development of industry and ...
from the
Industrial Research Institute Innovation Research Interchange (IRI) is a division of the National Association of Manufacturers, a nonprofit association based in Washington, D. C., United States. IRI was founded as a private non-profit in 1938 and merged with the NAM in 2022. IR ...
for his contributions to technology leadership *1981
American Institute of Chemists Gold Medal The American Institute of Chemists Gold Medal is the highest award of the American Institute of Chemists and has been awarded since 1926. It is presented annually to a person who has most encouraged the science of chemistry or the profession of ...


References


External links


Arthur A. Patchett, "Lewis Hastings Sarett", Biographical Memoirs of the National Academy of Sciences (2002)
*http://www.todayinsci.com/12/12_22.htm

December 27, 1999. 20th-century American chemists Jewish chemists Jewish American scientists National Medal of Science laureates Scientists from Illinois Princeton University alumni Northwestern University alumni People from Champaign, Illinois 20th-century American inventors 1917 births 1999 deaths 20th-century American Jews Members of the National Academy of Medicine {{US-scientist-stub