Lawrence S.B. Goldstein (born February 20, 1956, in

Buffalo, New York Buffalo is the second-largest city in the U.S. state of New York (behind only New York City) and the seat of Erie County. It is at the eastern end of Lake Erie, at the head of the Niagara River, and is across the Canadian border from South ...

) is a professor of cellular and molecular medicine at

University of California, San Diego The University of California, San Diego (UC San Diego or colloquially, UCSD) is a public university, public Land-grant university, land-grant research university in San Diego, California. Established in 1960 near the pre-existing Scripps Insti ...

and investigator with the

Howard Hughes Medical Institute The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fil ...

. He receives grant funding from the NIH, the Johns Hopkins ALS Center, the HighQ Foundation, and the

California Institute for Regenerative Medicine The California Institute for Regenerative Medicine (CIRM) was created in 2004 after 59% of California voters approved California Proposition 71: the Research and Cures Initiative, which allocated $3 billion to fund stem cell research in California ...

. In 2020 he was elected to the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...

Biography

Dr. Goldstein received his B.A. degree in biology and genetics from

UCSD The University of California, San Diego (UC San Diego or colloquially, UCSD) is a public university, public Land-grant university, land-grant research university in San Diego, California. Established in 1960 near the pre-existing Scripps Insti ...

in 1976 and his Ph.D. degree in genetics from the University of Washington, Seattle in 1980. He did postdoctoral research at the

University of Colorado at Boulder The University of Colorado Boulder (CU Boulder, CU, or Colorado) is a public research university in Boulder, Colorado. Founded in 1876, five months before Colorado became a state, it is the flagship university of the University of Colorado sys ...

from 1980 to 1983 and the

Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a private land-grant research university in Cambridge, Massachusetts. Established in 1861, MIT has played a key role in the development of modern technology and science, and is one of the ...

in 1983/1984. He was assistant, associate and full professor at

Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...

in the Department of Cellular and Developmental Biology from 1984 to 1993 and moved to

and

HHMI The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fil ...

in 1993. His awards include a Senior Scholar Award from the Ellison Medical Foundation, an

American Cancer Society The American Cancer Society (ACS) is a nationwide voluntary health organization dedicated to eliminating cancer. Established in 1913, the society is organized into six geographical regions of both medical and lay volunteers operating in more than ...

Faculty Research Award, and the Loeb Chair in Natural Sciences when he was at Harvard University. His research is focused on understanding the molecular mechanisms of intracellular movement in neurons and the role of transport failures in neurodegenerative diseases. His lab provided the first molecular descriptions of kinesin structure and organization, and also discovered important links between transport processes and diseases such as

Alzheimer's disease Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ...

and

Huntington's disease Huntington's disease (HD), also known as Huntington's chorea, is a neurodegenerative disease that is mostly inherited. The earliest symptoms are often subtle problems with mood or mental abilities. A general lack of coordination and an unst ...

. Dr. Goldstein has also had an active role in National Science policy. He has served on many public science advisory committees, has written about, spoken about, and been interviewed on numerous occasions on science issues by print and broadcast media, and has testified on a number of occasions in the U.S. House of Representatives and the Senate about NIH funding and stem cell research. As a cofounder and consultant of the biotechnology compan
Cytokinetics, Inc.
he has also had an active role in private industry. Goldstein has also served as elected secretary of the American Society for Cell Biology (ASCB).

References

External links

*https://alleninstitute.org/about/advisors/advisor-profiles/larry-goldstein/ * * {{DEFAULTSORT:Goldstein, Lawrence S.B. University of California, San Diego faculty University of California, San Diego alumni Stem cell researchers Medical educators American medical researchers University of Colorado Boulder alumni University of Washington alumni Harvard University faculty Living people 1956 births Howard Hughes Medical Investigators Members of the United States National Academy of Sciences

Biography

See also

References

External links