Lawrence S.B. Goldstein (born February 20, 1956, in
Buffalo, New York) is a professor of cellular and molecular medicine at
University of California, San Diego and investigator with the
Howard Hughes Medical Institute
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fil ...
. He receives grant funding from the
NIH, the Johns Hopkins ALS Center, the HighQ Foundation, and the
California Institute for Regenerative Medicine. In 2020 he was elected to the
National Academy of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
.
Biography
Dr. Goldstein received his B.A. degree in biology and genetics from
UCSD in 1976 and his Ph.D. degree in genetics from the
University of Washington, Seattle in 1980. He did postdoctoral research at the
University of Colorado at Boulder from 1980 to 1983 and the
Massachusetts Institute of Technology in 1983/1984. He was assistant, associate and full professor at
Harvard University in the Department of Cellular and Developmental Biology from 1984 to 1993 and moved to
UCSD and
HHMI
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fil ...
in 1993. His awards include a Senior Scholar Award from the Ellison Medical Foundation, an
American Cancer Society
The American Cancer Society (ACS) is a nationwide voluntary health organization dedicated to eliminating cancer. Established in 1913, the society is organized into six geographical regions of both medical and lay volunteers operating in more than ...
Faculty Research Award, and the Loeb Chair in Natural Sciences when he was at Harvard University.
His research is focused on understanding the molecular mechanisms of intracellular movement in neurons and the role of transport failures in neurodegenerative diseases. His lab provided the first molecular descriptions of
kinesin structure and organization, and also discovered important links between transport processes and diseases such as
Alzheimer's disease
Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ...
and
Huntington's disease. Dr. Goldstein has also had an active role in National Science policy. He has served on many public science advisory committees, has written about, spoken about, and been interviewed on numerous occasions on science issues by print and broadcast media, and has testified on a number of occasions in the U.S. House of Representatives and the Senate about NIH funding and stem cell research. As a cofounder and consultant of the biotechnology compan
Cytokinetics, Inc.he has also had an active role in private industry. Goldstein has also served as elected secretary of the
American Society for Cell Biology (ASCB).
See also
*
Through_the_Wormhole#Season_8_(2017)
References
External links
*https://alleninstitute.org/about/advisors/advisor-profiles/larry-goldstein/
*
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{{DEFAULTSORT:Goldstein, Lawrence S.B.
University of California, San Diego faculty
University of California, San Diego alumni
Stem cell researchers
Medical educators
American medical researchers
University of Colorado Boulder alumni
University of Washington alumni
Harvard University faculty
Living people
1956 births
Howard Hughes Medical Investigators
Members of the United States National Academy of Sciences