Laricitrin 5'-O-methyltransferase
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Laricitrin is an ''O''-methylated flavonol, a type of flavonoid. It is found in
red grape This list of grape varieties includes cultivated grapes, whether used for wine, or eating as a table grape, fresh or dried (raisin, currant, sultana). For a complete list of all grape species including those unimportant to agriculture, see Viti ...
(absent in white grape) and in ''
Vaccinium uliginosum ''Vaccinium uliginosum'' (bog bilberry, bog blueberry, northern bilberry or western blueberry) is a Eurasian and North American flowering plant in the genus ''Vaccinium'' within the heath family. Distribution ''Vaccinium uliginosum'' is native ...
'' (bog billberries). It is one of the phenolic compounds present in wine.


Metabolism

Laricitrin is formed from
myricetin Myricetin is a member of the flavonoid class of polyphenolic compounds, with antioxidant properties. Common dietary sources include vegetables (including tomatoes), fruits (including oranges), nuts, berries, tea, and red wine. Myricetin is structu ...
by the action of the enzyme
myricetin O-methyltransferase In enzymology, a myricetin O-methyltransferase () is an enzyme that catalyzes the chemical reaction :2 S-adenosyl-L-methionine + myricetin \rightleftharpoons 2 S-adenosyl-L-homocysteine + syringetin Thus, the two substrates of this enzyme are S ...
. It is further methylated by laricitrin 5'-O-methyltransferase into syringetin.


Glycosides

* Laricitrin 3-O-galactoside, found in grape * Laricitrin 3-glucoside found in ''
Larix sibirica ''Larix sibirica'', the Siberian larch or Russian larch, is a frost-hardy tree native to western Russia, from close to the Finnish border east to the Yenisei valley in central Siberia, where it hybridises with the Dahurian larch ''L. gmelinii' ...
'' * Laricitrin 3,5’-di-O-β-glucopyranoside, found in ''
Medicago littoralis ''Medicago littoralis'' is a plant species of the genus '' Medicago''. It is found primarily in the Mediterranean basin. It forms a symbiotic relationship with the bacterium ''Sinorhizobium meliloti'', which is capable of nitrogen fixation Ni ...
''Flavonoids isolated from ''Medicago littoralis'' Rhode (Fabaceae): their ecological and chemosystematic significance


References

{{flavonol O-methylated flavonols Resorcinols Catechols