LOX1 (gene)
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Linoleate 9S-lipoxygenase (, ''9-lipoxygenase'', ''9S-lipoxygenase'', ''linoleate 9-lipoxygenase'', ''LOX1 (gene)'', ''9S-LOX'') is an
enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ...
''linoleate:oxygen 9S-oxidoreductase''. This enzyme catalyses the following
chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
:
linoleate Linoleic acid (LA) is an organic compound with the formula COOH(CH2)7CH=CHCH2CH=CH(CH2)4CH3. Both alkene groups are ''cis''. It is a fatty acid sometimes denoted 18:2 (n-6) or 18:2 ''cis''-9,12. A linoleate is a salt or ester of this acid. L ...
+ O2 \rightleftharpoons (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate Linoleate 9S-lipoxygenase contains nonheme iron.


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* {{Portal bar, Biology, border=no EC 1.13.11