L. Emmett Holt, Jr.
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Luther Emmett Holt Jr. (1895–1974) was an American
pediatrician Pediatrics ( also spelled ''paediatrics'' or ''pædiatrics'') is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, paediatrics covers many of their youth until the ...
. As a faculty member at
Johns Hopkins University Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private university, private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hem ...
and later
New York University New York University (NYU) is a private research university in New York City. Chartered in 1831 by the New York State Legislature, NYU was founded by a group of New Yorkers led by then-Secretary of the Treasury Albert Gallatin. In 1832, the ...
, he performed extensive research in the field of pediatric nutrition. He received the
John Howland Award The John Howland Award is the highest honor bestowed by the American Pediatric Society (APS). Named in honor of John Howland (1873–1926), the award, with its accompanying medal, is presented annually by the American Pediatric Society for "dist ...
in 1966.


Biography

L. Emmett Holt Jr., the son of the pediatrician
Luther Emmett Holt Luther Emmett Holt (L. Emmett Holt, March 4, 1855 – January 14, 1924) was an American pediatrician and author, noted for writing ''The Care and Feeding of Children: A Catechism for the Use of Mothers and Children's Nurses'' in 1894. Born near ...
, was born in New York in 1895. He graduated from
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
in 1916 and finished
medical school A medical school is a tertiary educational institution, or part of such an institution, that teaches medicine, and awards a professional degree for physicians. Such medical degrees include the Bachelor of Medicine, Bachelor of Surgery (MBBS, M ...
at
Johns Hopkins University Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private university, private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hem ...
in 1920. As a student at Johns Hopkins, he worked in
William Henry Howell William Henry Howell (February 20, 1860 – February 6, 1945) was an American physiologist. He pioneered the use of heparin as a blood anti-coagulant. Early life William Henry Howell was born on February 20, 1860, in Baltimore, Maryland. He gra ...
's laboratory and assisted in the research that led to the discovery of
heparin Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. Since heparins depend on the activity of antithrombin, they are considered anticoagulants. Specifically it is also used in the treatm ...
. After graduating, he trained in pediatrics for a year at the Babies Hospital (now
Morgan Stanley Children's Hospital Morgan Stanley Children's Hospital of NewYork-Presbyterian (MSCH or CHONY) is a women's and children's hospital at 3959 Broadway, near West 165th Street, in the Washington Heights neighborhood of Manhattan, New York City. It is a part of NewYork-Pr ...
) in New York City before returning to Johns Hopkins in 1922. Holt practiced pediatrics at Johns Hopkins for 22 years under the leadership of Edwards A. Park and
John Howland John Howland (February 23, 1673) accompanied the English Separatists and other passengers when they left England on the to settle in Plymouth Colony. He was an indentured servant and in later years an executive assistant and personal secretary ...
. In 1943, he revised and published a new edition of his father's textbook ''Holt's Care and Feeding of Children''. He left Johns Hopkins in 1944 and returned to New York City, where he was appointed director of pediatrics at Bellevue Hospital and chair of the pediatrics department at the
New York University School of Medicine NYU Grossman School of Medicine is a medical school of New York University, a private research university in New York City. It was founded in 1841 and is one of two medical schools of the university, with the other being the Long Island School of ...
. In 1947, he organized the first International Congress of Pediatrics since the end of World War II; that same year, he was awarded the Order of the White Lion for recommending oral feeding as treatment during a Czechoslovak epidemic of diarrhea in children. His contributions to international pediatrics also earned him the Order of the Star of Jordan. Holt retired in 1960 and received the
John Howland Award The John Howland Award is the highest honor bestowed by the American Pediatric Society (APS). Named in honor of John Howland (1873–1926), the award, with its accompanying medal, is presented annually by the American Pediatric Society for "dist ...
, the highest honor given by the American Pediatric Society, in 1966. He died in
Myrtle Beach, South Carolina Myrtle Beach is a resort city on the east coast of the United States in Horry County, South Carolina. It is located in the center of a long and continuous stretch of beach known as "The Grand Strand" in the northeastern part of the state. Its y ...
, in 1974 at the age of 79.


Research

Holt began his research career as a medical student. At Johns Hopkins, he studied
calcium Calcium is a chemical element with the symbol Ca and atomic number 20. As an alkaline earth metal, calcium is a reactive metal that forms a dark oxide-nitride layer when exposed to air. Its physical and chemical properties are most similar to ...
metabolism and its association with rickets. His main field of research was pediatric nutrition. His research into fat absorption in premature babies led to the development of a popular
infant formula Infant formula, baby formula, or simply formula (American English); or baby milk, infant milk or first milk (British English), is a manufactured food designed and marketed for feeding to babies and infants under 12 months of age, usually prepar ...
, while his studies on the nutritional requirements of infants provided data for parenteral nutrition regimes. He also studied
fat emulsion Lipid emulsion or fat emulsion refers to an emulsion of lipid for human intravenous use, especially catering critically-ill patients that cannot consume food and administer their required nutrients enterally. It is often referred to by the brand n ...
as a method of intravenous nutrition, the treatment of
maple syrup urine disease Maple syrup urine disease (MSUD) is an autosomal recessive metabolic disorder affecting branched-chain amino acids. It is one type of organic acidemia. The condition gets its name from the distinctive sweet odor of affected infants' urine and ear ...
through diet control, and the human requirements for various B vitamins. Outside of nutrition, he also published research on topics including
lead poisoning Lead poisoning, also known as plumbism and saturnism, is a type of metal poisoning caused by lead in the body. The brain is the most sensitive. Symptoms may include abdominal pain, constipation, headaches, irritability, memory problems, inferti ...
,
leukemia Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ' ...
,
meningitis Meningitis is acute or chronic inflammation of the protective membranes covering the brain and spinal cord, collectively called the meninges. The most common symptoms are fever, headache, and neck stiffness. Other symptoms include confusion or ...
,
eczema Dermatitis is inflammation of the Human skin, skin, typically characterized by itchiness, erythema, redness and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become lichenification, thick ...
, and pertussis.


References

{{DEFAULTSORT:Holt, L. Emmett Jr. 1895 births 1974 deaths American pediatricians American medical researchers Johns Hopkins School of Medicine alumni Harvard University alumni New York University Grossman School of Medicine faculty Physicians from New York (state) Johns Hopkins Hospital physicians