Katherine S. Squibb
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Katherine Sprague Squibb (May 10, 1949 – August 18, 2018) was an American toxicologist who specialized in
metal toxicity Metal toxicity or metal poisoning is the toxic effect of certain metals in certain forms and doses on life. Some metals are toxic when they form poisonous soluble compounds. Certain metals have no biological role, i.e. are not essential minerals, o ...
. She was a faculty member at the
University of Maryland School of Medicine The University of Maryland School of Medicine (abbreviated UMSOM), located in Baltimore City, Maryland, U.S., is the medical school of the University of Maryland, Baltimore and is affiliated with the University of Maryland Medical Center and Me ...
and served as co-director of the University System of Maryland's graduate program in toxicology.


Life

Katherine Anne Sprague was born May 10, 1949 in
New Brunswick, New Jersey New Brunswick is a city (New Jersey), city in and the county seat, seat of government of Middlesex County, New Jersey, Middlesex County, in the U.S. state of New Jersey.agronomist and homemaker Margarete Hardegen Sprauge. Raised in the
Dayton Dayton () is the sixth-largest city in the U.S. state of Ohio and the county seat of Montgomery County. A small part of the city extends into Greene County. The 2020 U.S. census estimate put the city population at 137,644, while Greater Da ...
section of South Brunswick, Squibb graduated from South Brunswick High School. She majored in biochemistry at University of Wisconsin–Madison, graduating in 1971. Squibb married fellow toxicologist on August 21, 1971. Squibb completed a master's and Ph.D. (1977) in biochemistry at Rutgers University. Her dissertation was titled ''Control of hepatic metallothionein synthesis by zinc and cadmium''. She was a postdoctoral researcher at the
National Institute of Environmental Health Sciences The National Institute of Environmental Health Sciences (NIEHS) conducts research into the effects of the environment on human disease, as one of the 27 institutes and centers of the National Institutes of Health (NIH). It is located in the Rese ...
. In 1984, Squibb joined the New York University Medical Center's Institute of Environmental Medicine. In 1993, she joined the department of medicine at the
University of Maryland School of Medicine The University of Maryland School of Medicine (abbreviated UMSOM), located in Baltimore City, Maryland, U.S., is the medical school of the University of Maryland, Baltimore and is affiliated with the University of Maryland Medical Center and Me ...
. She worked as the co-director of the University System of Maryland's graduate program in toxicology. Squibb led research on
metal toxicity Metal toxicity or metal poisoning is the toxic effect of certain metals in certain forms and doses on life. Some metals are toxic when they form poisonous soluble compounds. Certain metals have no biological role, i.e. are not essential minerals, o ...
"and metabolism elucidated ways in which metals such as cadmium, lead, and depleted uranium target specific organ systems." In the fall of 2015, Squibb received the achievement graduate education award from the University of Maryland's graduate program in life sciences. Squibb had a daughter and son. She died August 18, 2018 in Columbia, Maryland of
Alzheimer's disease Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ...
.


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* * * * {{DEFAULTSORT:Squibb, Katherine S. 1949 births 2018 deaths People from New Brunswick, New Jersey People from South Brunswick, New Jersey Scientists from New Jersey University of Wisconsin–Madison alumni Rutgers University alumni South Brunswick High School (New Jersey) alumni New York University faculty University of Maryland School of Medicine faculty American toxicologists 20th-century American women scientists 21st-century American women scientists Deaths from Alzheimer's disease