Karol Sikora
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Karol Sikora (born 17 June 1948) is a British physician specialising in
oncology Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ó ...
, who has been described as a leading world authority on
cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...
. He was a founder and medical director of
Rutherford Health Rutherford Health was a private oncology provider founded by Mike Moran and Karol Sikora in 2015, with investment from Neil Woodford and the Wales Life Sciences Investment Fund, to develop proton therapy facilities in the United Kingdom and elsew ...
, a company that provided
proton therapy In medicine, proton therapy, or proton radiotherapy, is a type of particle therapy that uses a beam of protons to irradiate diseased tissue, most often to treat cancer. The chief advantage of proton therapy over other types of external beam ra ...
services, and is Director of Medical Oncology at the
Bahamas The Bahamas (), officially the Commonwealth of The Bahamas, is an island country within the Lucayan Archipelago of the West Indies in the Atlantic Ocean, North Atlantic. It takes up 97% of the Lucayan Archipelago's land area and is home to ...
Cancer Centre. He is currently Professor of Medicine at the
University of Buckingham , mottoeng = Flying on Our Own Wings , established = 1973; as university college1983; as university , type = Private , endowment = , administrative_staff = 97 academic, 103 support , chance ...
, and a partner in and dean of Buckingham's medical school.


Early life

Karol Sikora was born in 1948. His father was a captain in the Polish Army who arrived in
Great Britain Great Britain is an island in the North Atlantic Ocean off the northwest coast of continental Europe. With an area of , it is the largest of the British Isles, the largest European island and the ninth-largest island in the world. It is ...
during
World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...
and his mother was a Scottish schoolteacher. His childhood was spent in
Edinburgh Edinburgh ( ; gd, Dùn Èideann ) is the capital city of Scotland and one of its 32 Council areas of Scotland, council areas. Historically part of the county of Midlothian (interchangeably Edinburghshire before 1921), it is located in Lothian ...
,
Stafford Stafford () is a market town and the county town of Staffordshire, in the West Midlands region of England. It lies about north of Wolverhampton, south of Stoke-on-Trent and northwest of Birmingham. The town had a population of 70,145 in t ...
and
London London is the capital and largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary down to the North Sea, and has been a majo ...
. He attended Dulwich College on a
London County Council London County Council (LCC) was the principal local government body for the County of London throughout its existence from 1889 to 1965, and the first London-wide general municipal authority to be directly elected. It covered the area today kno ...
scholarship before going to
Corpus Christi College, Cambridge Corpus Christi College (full name: "The College of Corpus Christi and the Blessed Virgin Mary", often shortened to "Corpus"), is a constituent college of the University of Cambridge. From the late 14th century through to the early 19th century ...
where he became a Foundation Scholar and obtained a
double first The British undergraduate degree classification system is a grading structure for undergraduate degrees or bachelor's degrees and integrated master's degrees in the United Kingdom. The system has been applied (sometimes with significant variati ...
. He received his PhD at
Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is consider ...
, where he also served a clinical fellowship.


Career

After leaving Stanford University, Sikora returned to Cambridge to direct the
Ludwig Institute for Cancer Research Ludwig Cancer Research is an international community of scientists focused on cancer research, with the goal of preventing and controlling cancer. It encompasses the Ludwig Institute for Cancer Research, an international non-profit organization f ...
. From 1985 to 1997, he served as the clinical director for cancer services at
Hammersmith Hospital Hammersmith Hospital, formerly the Military Orthopaedic Hospital, and later the Special Surgical Hospital, is a major teaching hospital in White City, West London. It is part of Imperial College Healthcare NHS Trust in the London Borough of H ...
in London, where he established a cancer research laboratory, and was Professor of International Cancer Medicine at the Royal Postgraduate Medical School, later the Imperial College School of Medicine. During the 1990s Sikora was also deputy director of clinical research at charity the Imperial Cancer Research Fund, the predecessor to Cancer Research UK. In 1997 he became the Chief of the Cancer Program of the
World Health Organization The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of h ...
before resigning in 1999 over a disagreement with the UN regarding their proposals to restructure work on non-communicable diseases, stating this would create a "top-heavy bureaucracy". He served as the Vice-President of Global Clinical Research in Oncology at the
Pharmacia Corporation Pharmacia was a pharmaceutical and biotechnological company in Sweden that merged with the American pharmaceutical company Upjohn in 1995. History Pharmacia company was founded in 1911 in Stockholm, Sweden by pharmacist Gustav Felix Grönfeldt ...
from 1999 to 2002. He has also been a member of the UK Health Department's Expert Advisory Group on Cancer, as well as the Committee on Safety of Medicines. In 2022, Rutherford Health, a company he founded in 2015 and was Medical Director of, was liquidated. He is dean of the
University of Buckingham , mottoeng = Flying on Our Own Wings , established = 1973; as university college1983; as university , type = Private , endowment = , administrative_staff = 97 academic, 103 support , chance ...
's medical school, the only private medical school in the UK. He is also a member of the Oncology Scientific Advisory Board at biopharmaceutical company
Cyclacel {{Infobox company , , name = Cyclacel Pharmaceuticals, Inc. , logo = Cyclacel.png , type = Public , traded_as = {{NASDAQ, CYCC , foundation = 1997 , location = Berkeley Heights, New Jersey, U.S. , key_people = Spiro Rombotis, CEO David P. ...
Limited, and serves as an oncology consultant for AstraZeneca. Sikora also served as the Interim Director of Radiation Oncology for the newly constructed Cancer Centre Eastern Caribbean in Antigua. He is an unpaid member of the Meat Advisory Panel, a group of scientists that provide information and advice about meat as part of a balanced diet, and is patron of several cancer and other charities, including Medical Detection Dogs, which trains dogs to detect the odour of human disease to assist in diagnosis. Sikora has published over 300 papers and written or edited 20 books, notably the "standard" UK postgraduate textbook ''Treatment of Cancer''. He appeared in Michael Apted's 1999 documentary film ''
Me & Isaac Newton ''Me & Isaac Newton'' is a 1999 documentary directed by Michael Apted and produced by Clear Blue Sky Productions. Synopsis With a lightly humorous approach, the film explores human advances in the field of sciences. Both Apted and Paul G. Allen, ...
'', which featured interviews with scientists and researchers.


Criticism of National Health Service

Sikora is known for his outspoken views on
National Health Service The National Health Service (NHS) is the umbrella term for the publicly funded healthcare systems of the United Kingdom (UK). Since 1948, they have been funded out of general taxation. There are three systems which are referred to using the " ...
(NHS) reform, and has written for ''
the Times ''The Times'' is a British daily national newspaper based in London. It began in 1785 under the title ''The Daily Universal Register'', adopting its current name on 1 January 1788. ''The Times'' and its sister paper ''The Sunday Times'' (fou ...
'', ''
the Observer ''The Observer'' is a British newspaper published on Sundays. It is a sister paper to ''The Guardian'' and ''The Guardian Weekly'', whose parent company Guardian Media Group Limited acquired it in 1993. First published in 1791, it is the w ...
'', the ''
New Statesman The ''New Statesman'' is a British political and cultural magazine published in London. Founded as a weekly review of politics and literature on 12 April 1913, it was at first connected with Sidney and Beatrice Webb and other leading members ...
'', and other publications on the subject. He has been critical of the quality of cancer care available on the NHS and has argued for its restructuring, suggesting that while the UK spends as much per patient on cancer care as the rest of Europe, survival rates are substantially lower: "there are 10 new drugs routinely available in
Boulogne Boulogne-sur-Mer (; pcd, Boulonne-su-Mér; nl, Bonen; la, Gesoriacum or ''Bononia''), often called just Boulogne (, ), is a coastal city in Northern France. It is a sub-prefecture of the department of Pas-de-Calais. Boulogne lies on the ...
but not in
Brighton Brighton () is a seaside resort and one of the two main areas of the City of Brighton and Hove in the county of East Sussex, England. It is located south of London. Archaeological evidence of settlement in the area dates back to the Bronze A ...
". In a 2017 '' Newsnight'' opinion piece, he described the NHS as "the last bastion of
communism Communism (from Latin la, communis, lit=common, universal, label=none) is a far-left sociopolitical, philosophical, and economic ideology and current within the socialist movement whose goal is the establishment of a communist society, a s ...
– it is a monolithic, unmanageable and inefficient system ..the staff are great but the system is not". He proposed instead regarding it as a tax-based insurance scheme covering "basic costs", and allowing private providers to enter the market. An interview with Sikora, in which he suggested the NHS system led to patients losing control over their own healthcare, was featured in a May 2009
Republican Party Republican Party is a name used by many political parties around the world, though the term most commonly refers to the United States' Republican Party. Republican Party may also refer to: Africa *Republican Party (Liberia) * Republican Part ...
attack ad in the US during US President
Barack Obama Barack Hussein Obama II ( ; born August 4, 1961) is an American politician who served as the 44th president of the United States from 2009 to 2017. A member of the Democratic Party, Obama was the first African-American president of the U ...
's push to enact healthcare reform. Sikora later told ''
The Guardian ''The Guardian'' is a British daily newspaper. It was founded in 1821 as ''The Manchester Guardian'', and changed its name in 1959. Along with its sister papers ''The Observer'' and ''The Guardian Weekly'', ''The Guardian'' is part of the Gu ...
'' that he did not know his interview would be used in the ad campaign, and that he agreed with Obama that the main problems with the American system were "the high cost of medical treatment" and the large number of uninsured people. In a piece published online by the '' New Hampshire Union Leader'' the same day as the advertisement, Sikora was referred to as professor of oncology at
Imperial College Imperial College London (legally Imperial College of Science, Technology and Medicine) is a public research university in London, United Kingdom. Its history began with Prince Albert, consort of Queen Victoria, who developed his vision for a cu ...
. This led Imperial to seek legal advice to stop Sikora being referred to as a current professor of cancer medicine at Imperial; a claim that he was also alleged to have made earlier in the previous five years. On 29 January 2009, Sikora was said to have introduced himself to a Commons health select committee as "...professor of oncology at Imperial College for 22 years." Prior to 2004, Sikora had held the honorary post of Professor of Cancer Medicine at the Imperial College School of Medicine, Hammersmith, having been the founding chair of cancer medicine at its predecessor, the Royal Postgraduate Medical School. In the context of the National Institute for Health and Care Excellence (NICE) considering whether to apply age criteria when prescribing expensive drugs, he suggested that "within limited budgets" younger patients might be given priority over the frail elderly.


Views on alternative medicine

Sikora has in the past suggested that
alternative Alternative or alternate may refer to: Arts, entertainment and media * Alternative (''Kamen Rider''), a character in the Japanese TV series ''Kamen Rider Ryuki'' * ''The Alternative'' (film), a 1978 Australian television film * ''The Alternative ...
or "complementary" medicine might have some utility in providing psychological care to cancer patients;''British Medical Journal'' 1989;298:1583 he has commented "I personally don’t think that complementary medicine is itself a cure ..but I do believe it ..allows you to get on top of the fact that you have cancer and live with it in a way that doesn’t disturb you psychologically too much". He has stated that after being invited in the 1980s to work with the Bristol Cancer Help Centre, which employed complementary therapists alongside conventional medicine, he came to believe that complementary therapies such as counselling or acupuncture could "help patients to complete their course of orthodox treatment" and "improve quality of life"."Empowering the patient", ''International Therapist'', 89 (Jul 2009), 58 Sikora was a Foundation Fellow of
Prince Charles Charles III (Charles Philip Arthur George; born 14 November 1948) is King of the United Kingdom and the 14 other Commonwealth realms. He was the longest-serving heir apparent and Prince of Wales and, at age 73, became the oldest person to ...
' now-defunct alternative medicine lobby group
The Prince's Foundation for Integrated Health The Foundation for Integrated Health (FIH) was a controversial charity run by King Charles III (then Prince of Wales) founded in 1993. The foundation promoted complementary and alternative medicine, preferring to use the term " integrated health", ...
. He is also a "professional member" of the College of Medicine, a patient-oriented healthcare lobby group also linked to the Prince of Wales that appeared shortly after the collapse of the FIH. Correspondents to the ''
British Medical Journal ''The BMJ'' is a weekly peer-reviewed medical trade journal, published by the trade union the British Medical Association (BMA). ''The BMJ'' has editorial freedom from the BMA. It is one of the world's oldest general medical journals. Origi ...
'' have criticised the College for its promotion of alternative medicine, claims which it has contested. Sikora is on the advisory panel of complementary cancer care charity Penny Brohn Cancer Care (formerly the Bristol Cancer Help Centre) of which Prince Charles is a patron, and is a patron of the Iain Rennie Hospice at Home. The pharmacologist
David Colquhoun David Colquhoun (born 19 July 1936) is a British pharmacologist at University College London (UCL). He has contributed to the general theory of receptor and synaptic mechanisms, and in particular the theory and practice of single ion channel f ...
noted that the School of Medicine at Buckingham University, of which Sikora is Dean, had briefly offered a diploma in "integrated medicine" (a
euphemism A euphemism () is an innocuous word or expression used in place of one that is deemed offensive or suggests something unpleasant. Some euphemisms are intended to amuse, while others use bland, inoffensive terms for concepts that the user wishes ...
for alternative medicine) run by the "Faculty of Integrated Medicine", adding that Sikora's own views on the subject were a "mystery wrapped in an enigma". Sikora has however, elsewhere been critical of alternative medicine; after Parliament member Lord Maurice Saatchi proposed a bill allowing doctors to use unproven experimental therapies, he noted that this could give false hope to terminally ill patients. He has contrasted therapies having "a profound psychological base", such as counselling, with others "founded on completely spurious pseudoscientific logic".


Release of Abdelbaset al-Megrahi

In September 2009, the man convicted of the
Pan Am Flight 103 Pan Am Flight 103 was a regularly scheduled Pan Am transatlantic flight from Frankfurt to Detroit via a stopover in London and another in New York City. The transatlantic leg of the route was operated by ''Clipper Maid of the Seas'', a Boeing ...
bombing,
Abdelbaset al-Megrahi ) , birth_date = , birth_place = Tripoli, Kingdom of Libya , death_date = , death_place = Tripoli, Libya , cause = Prostate cancer , nationality = Libyan , race = Arab , g ...
, was released from a Scottish prison on compassionate grounds. ''
The Daily Telegraph ''The Daily Telegraph'', known online and elsewhere as ''The Telegraph'', is a national British daily broadsheet newspaper published in London by Telegraph Media Group and distributed across the United Kingdom and internationally. It was fo ...
'' reported that Sikora, along with Professors
Jonathan Waxman Jonathan Waxman is an American chef who was one of the pioneers of California cuisine and is credited with being the first to bring its style, fusing French cooking techniques with the freshest local ingredients, to New York. Biography Born in 19 ...
and Ibrahim Sharif, was one of three doctors hired by the
Libya Libya (; ar, ليبيا, Lībiyā), officially the State of Libya ( ar, دولة ليبيا, Dawlat Lībiyā), is a country in the Maghreb region in North Africa. It is bordered by the Mediterranean Sea to the north, Egypt to Egypt–Libya bo ...
n government to assess Megrahi's condition prior to the release. Sikora's report concluded that Megrahi would "likely" die within three months due to terminal
prostate cancer Prostate cancer is cancer of the prostate. Prostate cancer is the second most common cancerous tumor worldwide and is the fifth leading cause of cancer-related mortality among men. The prostate is a gland in the male reproductive system that sur ...
; Sharif agreed and Waxman conceded Megrahi did not have long to live. Megrahi outlived the prognosis and died on 20 May 2012, two years and nine months after his release. Sikora later denied that he had been pressured by Libya to agree Megrahi had under three months to live: "on the balance of probability, you could justify that
laim Laim (Central Bavarian: ''Loam'') is a district of Munich, Germany, forming the 25th borough of the city. Inhabitants: c. 49.000 (2005) History Originally its own independent locality, Laim was in existence before Munich. It was first documented ...
but you couldn't say he was definitely going to be dead in three months". The Scottish government confirmed Sikora's report was not used by the Scottish Justice Minister in making the decision to release Megrahi, which was instead based on their own medical reports and input from the parole board and governor. Sikora has since complained about the way journalists have reported his views and stated that he was not paid to make claims, and there was probably a less than one percent chance of Megrahi living 10 years.


Commentary on UK response to COVID-19

Sikora has commented in the UK media on the UK's public health response to COVID-19, expressing concerns that policies of lockdown could impact treatment of other conditions, particularly cancer.Blakely, Rhys
This is an unfolding disaster. My advice? Don’t get cancer in 2020
''The Times'', 22-08-20
Sikora,
Britain faces a deadly new cancer crisis thanks to lockdown and we are being too slow to react to it
''Daily Telegraph'', 06-07-20
On 21 September 2020, Sikora alongside Carl Heneghan, Sunetra Gupta and 28 other signatories, wrote an open letter to top UK government officials asking for a rethink to the Covid strategy. It called for a targeted approach to lockdowns advising that only over-65s and the vulnerable should be shielded.Boris must urgently rethink his Covid strategy
''The Spectator'', 21-09-20


Works

* ''
Interferon Interferons (IFNs, ) are a group of signaling proteins made and released by host cells in response to the presence of several viruses. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten the ...
and cancer'', 1983 * ''Clinical Physiology'' (with Campbell, Dickinson, Slater and Edwards), 1984 * ''Endocrine Problems in Cancer'' (with Roland T. Jung), 1984 * ''Monoclonal Antibodies'' (with Howard Smedley), 1984 * ''Molecular Biology and Human Disease'' (with Sandy McCleod), 1984 * ''Cancer – what it is and how it's treated'' (with Rob Stepney and Howard Smedley), 1985 * ''Cancer – a study guide'' (with Howard Smedley), 1985 * ''Cancer'' (with Howard Smedley), 1988 * ''The Molecular Biology of Cancer'' (with Jonathan Waxman), 1989 * ''Fight Cancer'' (with Hilary Thomas), 1989 * ''Treatment of Cancer'' (with Keith Halnan and Pat Price), 1990, 1995, 2002, 2008 * ''Genes and Cancer'' (editor), 1990 * ''The cancer cell'' (with Gerard Evan and James Watson), 1991 * ''Human genetic therapy'' (with Jonathan Harris), 1994 * ''Cancer: a positive approach'' (with Hilary Thomas), 1995 * ''Handbook of oncology'' (with Victor Barley and Jeff Tobias), 1998, 2004 * ''The Realities of Rationing'' (with John Spiers et al.), 1999 * ''The cancer survival kit'' (with Rosy Daniel), 2004 * ''Cancer 2025: The future of cancer care'' (editor), 2005 * ''Economics of Cancer Care'' (with Nick Bosanquet), 2006


References


External links


University of Buckingham profile
{{DEFAULTSORT:Sikora, Karol British oncologists 21st-century British medical doctors People educated at Dulwich College Alumni of Corpus Christi College, Cambridge Fellows of Corpus Christi College, Cambridge Academics of the University of Buckingham Stanford University faculty 1948 births Living people British people of Polish descent