Kynurenine—oxoglutarate transaminase 1 is an
enzyme that in humans is encoded by the ''CCBL1''
gene.
It is one of the
Kynurenine—oxoglutarate transaminase
In enzymology, a kynurenine-oxoglutarate transaminase () is an enzyme that catalyzes the chemical reaction
:-kynurenine + 2-oxoglutarate 4-(2-aminophenyl)-2,4-dioxobutanoate + -glutamate
Thus, the two substrates of this enzyme are -kynurenin ...
s.
This gene encodes a cytosolic
enzyme which is responsible for the
metabolism of
cysteine
Cysteine (symbol Cys or C; ) is a semiessential proteinogenic amino acid with the formula . The thiol side chain in cysteine often participates in enzymatic reactions as a nucleophile.
When present as a deprotonated catalytic residue, sometime ...
conjugates of certain
halogenated alkenes and
alkanes. This metabolism leads to the formation of reactive metabolites which can lead to
nephrotoxicity and
neurotoxicity.
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