Keratin 3 also known as ''cytokeratin 3'' is a protein that in humans is encoded by the ''KRT3'' gene. Keratin 3 is a

type II cytokeratin Type II keratins (or Type II cytokeratins) constitutes the Type II intermediate filaments (IFs) of the intracytoplasmatic cytoskeleton, which is present in all mammalian epithelial cells. The type 2 cytokeratins consist of basic or neutral, high mol ...

. It is specifically found in the corneal epithelium together with

keratin 12 Keratin 12 is a protein that in humans is encoded by the KRT12 gene. Keratin 12 is keratin Keratin () is one of a family of structural fibrous proteins also known as ''scleroproteins''. Alpha-keratin (α-keratin) is a type of keratin found ...

. Mutations in the KRT3 encoding this protein have been associated with

Meesmanns Corneal Dystrophy Meesmann corneal dystrophy (MECD) is a rare hereditary autosomal dominant disease that is characterized as a type of corneal dystrophy and a keratin disease. MECD is characterized by the formation of microcysts in the outermost layer of the cornea, ...

References

Keratins {{Gene-12-stub