James J. Champoux (died 13 May 2019) was an American microbiologist who worked at

University of Washington The University of Washington (UW, simply Washington, or informally U-Dub) is a public research university in Seattle, Washington. Founded in 1861, Washington is one of the oldest universities on the West Coast; it was established in Seattle a ...

and an Elected Fellow of the

American Association for the Advancement of Science The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific respons ...

Education

He earned his B.S. at University of Washington and his Ph.D. at

Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is consider ...

Research

His interests were retroviruses and topoisomerases and his highest cited paper is ''DNA Topoisomerases: Structure, Function, and Mechanism'' at 2260 times, according to Google Scholar.

Publications

*Effects of DNA and protein size on substrate cleavage by human tyrosyl-DNA phosphodiesterase 1. Interthal H, Champoux JJ The Biochemical Journal. 2011 Jun; 436 3: 559-66 *Multiple nucleotide preferences determine cleavage-site recognition by the HIV-1 and M-MuLV RNases H. Schultz SJ, Zhang M, Champoux JJ Journal of Molecular Biology. 2010 Mar; 397 1: 161-78 *Preferred sequences within a defined cleavage window specify DNA 3' end-directed cleavages by retroviral RNases H. Schultz SJ, Zhang M, Champoux JJ The Journal of Biological Chemistry. 2009 Nov; 284 47: 32225-38 *Assays for the preferential binding of human topoisomerase I to supercoiled DNA. Yang Z, Champoux JJ Methods in Molecular Biology. 2009 ; 582 : 49-57 *Mutational analysis of the preferential binding of human topoisomerase I to supercoiled DNA. Yang Z, Carey JF, Champoux JJ The FEBS journal. 2009 Oct; 276 20: 5906-19

References

{{DEFAULTSORT:Champoux, James Year of birth missing (living people) Living people Fellows of the American Association for the Advancement of Science University of Washington faculty American microbiologists