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Jakub Karol Parnas, also known as Yakov Oskarovich Parnas (russian: Яков Оскарович Парнас) (January 16, 1884 – January 29, 1949) was a prominent
Polish Polish may refer to: * Anything from or related to Poland, a country in Europe * Polish language * Poles Poles,, ; singular masculine: ''Polak'', singular feminine: ''Polka'' or Polish people, are a West Slavic nation and ethnic group, w ...
Soviet The Soviet Union,. officially the Union of Soviet Socialist Republics. (USSR),. was a transcontinental country that spanned much of Eurasia from 1922 to 1991. A flagship communist state, it was nominally a federal union of fifteen nation ...
biochemist who contributed to the discovery of the Embden–Meyerhof–Parnas pathway, together with
Otto Fritz Meyerhof Otto Fritz Meyerhof (; April 12, 1884 – October 6, 1951) was a German physician and biochemist who won the 1922 Nobel Prize in Physiology and Medicine. Biography Otto Fritz Meyerhof was born in Hannover, at Theaterplatz 16A (now:Rathenaustra ...
and Gustav Georg Embden. He became a
Soviet The Soviet Union,. officially the Union of Soviet Socialist Republics. (USSR),. was a transcontinental country that spanned much of Eurasia from 1922 to 1991. A flagship communist state, it was nominally a federal union of fifteen nation ...
activist after the annexation of Western Ukraine in 1939. He was arrested during the Jewish Anti-Fascist Committee affair in 1949 and died in the prison, reportedly of heart attack.


Biography

Parnas was born in 1884 in
Tarnopol Ternópil ( uk, Тернопіль, Ternopil' ; pl, Tarnopol; yi, טאַרנאָפּל, Tarnopl, or ; he, טארנופול (טַרְנוֹפּוֹל), Tarnopol; german: Tarnopol) is a city in the west of Ukraine. Administratively, Ternopi ...
, at that time part of the Austro-Hungarian Empire, in the province of Galicia (now split between Poland and Ukraine), to
Jewish Jews ( he, יְהוּדִים, , ) or Jewish people are an ethnoreligious group and nation originating from the Israelites Israelite origins and kingdom: "The first act in the long drama of Jewish history is the age of the Israelites""The ...
parents. He graduated from the Royal Technical College of Charlottenburg in 1904. From 1920 to 1941, he was head of the Institute of the Medical Chemistry at
Lviv University The University of Lviv ( uk, Львівський університет, Lvivskyi universytet; pl, Uniwersytet Lwowski; german: Universität Lemberg, briefly known as the ''Theresianum'' in the early 19th century), presently the Ivan Franko Na ...
. He traveled across Europe, collaborating with universities in
Cambridge Cambridge ( ) is a College town, university city and the county town in Cambridgeshire, England. It is located on the River Cam approximately north of London. As of the 2021 United Kingdom census, the population of Cambridge was 145,700. Cam ...
,
Naples Naples (; it, Napoli ; nap, Napule ), from grc, Νεάπολις, Neápolis, lit=new city. is the regional capital of Campania and the third-largest city of Italy, after Rome and Milan, with a population of 909,048 within the city's adminis ...
, Strasbourg,
Ghent Ghent ( nl, Gent ; french: Gand ; traditional English: Gaunt) is a city and a municipality in the Flemish Region of Belgium. It is the capital and largest city of the East Flanders province, and the third largest in the country, exceeded i ...
and Zurich. He was a member of the
German Academy of Sciences Leopoldina The German National Academy of Sciences Leopoldina (german: Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften), short Leopoldina, is the national academy of Germany, and is located in Halle (Saale). Founde ...
, Corresponding Member of the
Polish Academy of Sciences The Polish Academy of Sciences ( pl, Polska Akademia Nauk, PAN) is a Polish state-sponsored institution of higher learning. Headquartered in Warsaw, it is responsible for spearheading the development of science across the country by a society o ...
, as well an honorary doctor of
Sorbonne University Sorbonne University (french: Sorbonne Université; la Sorbonne: 'the Sorbonne') is a public research university located in Paris, France. The institution's legacy reaches back to 1257 when Sorbonne College was established by Robert de Sor ...
and the
University of Athens The National and Kapodistrian University of Athens (NKUA; el, Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών, ''Ethnikó ke Kapodistriakó Panepistímio Athinón''), usually referred to simply as the Univers ...
. After the
Soviet invasion of Poland The Soviet invasion of Poland was a military operation by the Soviet Union without a formal declaration of war. On 17 September 1939, the Soviet Union invaded Poland from the east, 16 days after Nazi Germany invaded Poland from the west. Subs ...
and annexation of
Western Ukraine Western Ukraine or West Ukraine ( uk, Західна Україна, Zakhidna Ukraina or , ) is the territory of Ukraine linked to the former Kingdom of Galicia–Volhynia, which was part of the Polish–Lithuanian Commonwealth, the Austria ...
in 1939 by the
Soviet Union The Soviet Union,. officially the Union of Soviet Socialist Republics. (USSR),. was a List of former transcontinental countries#Since 1700, transcontinental country that spanned much of Eurasia from 1922 to 1991. A flagship communist state, ...
, Parnas remained in
Lviv Lviv ( uk, Львів) is the largest city in western Ukraine, and the seventh-largest in Ukraine, with a population of . It serves as the administrative centre of Lviv Oblast and Lviv Raion, and is one of the main cultural centres of Ukrain ...
to continue his work in the institute. He also started collaborating with the Soviet authorities by taking on a political role in the communist District
Soviet The Soviet Union,. officially the Union of Soviet Socialist Republics. (USSR),. was a transcontinental country that spanned much of Eurasia from 1922 to 1991. A flagship communist state, it was nominally a federal union of fifteen nation ...
Worker's Delegation. In 1941, after the
German invasion of the Soviet Union Operation Barbarossa (german: link=no, Unternehmen Barbarossa; ) was the invasion of the Soviet Union by Nazi Germany and many of its Axis allies, starting on Sunday, 22 June 1941, during the Second World War. The operation, code-named afte ...
, Parnas was evacuated deeper into the USSR and remained there for the rest of his life. Only a few days after his departure,
Lviv Lviv ( uk, Львів) is the largest city in western Ukraine, and the seventh-largest in Ukraine, with a population of . It serves as the administrative centre of Lviv Oblast and Lviv Raion, and is one of the main cultural centres of Ukrain ...
(Lwów) was occupied by the
Nazi Germany Nazi Germany (lit. "National Socialist State"), ' (lit. "Nazi State") for short; also ' (lit. "National Socialist Germany") (officially known as the German Reich from 1933 until 1943, and the Greater German Reich from 1943 to 1945) was ...
army, who
massacred A massacre is the killing of a large number of people or animals, especially those who are not involved in any fighting or have no way of defending themselves. A massacre is generally considered to be morally unacceptable, especially when per ...
approximately 45 Lwów professors. Parnas was a member of the
Union of Polish Patriots Union of Polish Patriots (''Society of Polish Patriots'', pl, Związek Patriotów Polskich, ZPP, russian: Союз Польских Патриотов, СПП) was a political body created by Polish communists in the Soviet Union in 1943. The ...
. In the Soviet Union, Parnas met
Joseph Stalin Joseph Vissarionovich Stalin (born Ioseb Besarionis dze Jughashvili; – 5 March 1953) was a Georgian revolutionary and Soviet political leader who led the Soviet Union from 1924 until his death in 1953. He held power as General Secretar ...
, and received his own laboratory. He became an
Academician An academician is a full member of an artistic, literary, engineering, or scientific academy. In many countries, it is an honorific title used to denote a full member of an academy that has a strong influence on national scientific life. In syst ...
of the
Academy of Sciences of the USSR The Academy of Sciences of the Soviet Union was the highest scientific institution of the Soviet Union from 1925 to 1991, uniting the country's leading scientists, subordinated directly to the Council of Ministers of the Soviet Union (until 1946 ...
and a founding member of the Academy of Medical Sciences of the USSR. Despite his achievements and popularity, Parnas was falsely accused of being a spy of the
West West or Occident is one of the four cardinal directions or points of the compass. It is the opposite direction from east and is the direction in which the Sun sets on the Earth. Etymology The word "west" is a Germanic word passed into some ...
and arrested by the
KGB The KGB (russian: links=no, lit=Committee for State Security, Комитет государственной безопасности (КГБ), a=ru-KGB.ogg, p=kəmʲɪˈtʲet ɡəsʊˈdarstvʲɪn(ː)əj bʲɪzɐˈpasnəsʲtʲɪ, Komitet gosud ...
on January 28, 1949. According to KGB's archives, he died during his first interrogation at
Lubyanka prison The Lubyanka ( rus, Лубянка, p=lʊˈbʲankə) is the popular name for the building which contains the headquarters of the FSB, and its affiliated prison, on Lubyanka Square in the Meshchansky District of Moscow, Russia. It is a large Ne ...
"from a
heart attack A myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to the coronary artery of the heart, causing damage to the heart muscle. The most common symptom is chest pain or discomfort which ma ...
" on January 29, 1949.


Achievements

Parnas's major work was the study of the mechanisms of
carbohydrate In organic chemistry, a carbohydrate () is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water) and thus with the empirical formula (where ''m'' may or m ...
metabolism Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run c ...
in muscle tissue. Together with Władysław Baranowski, he discovered the process of phosphorolysis.http://nobelprize.org/nobel_prizes/medicine/laureates/1947/cori-lecture.pdf. Parnas also made a major contribution to the theoretical analysis of glycolysis.


Legacy

Parnas is honored by the Polish–Ukrainian Parnas Conference organized by the Polish and Ukrainian Biochemical Societies, which has been held every two years since 1996.Postepy Biochemii Vol. 43 No. 5 1997 p.311 In 2009, Prof. Andrzej Dżugaj, the President of the Polish Biochemical Society, suggested to include Israeli biochemists to the Conference organizers to acknowledge the roots of J.K. Parnas and his co-workers. Thanks to his efforts, the VIII Parnas Conference took place in 2011, in Poland, for the first time, with the joint organization by three national Societies, Polish, Ukrainian and Israel. In 2013 the conference took place in Jerusalem (organized by Israeli Society for Biochemistry and Molecular Biology). The next Parnas conference took place in Poland at 10–12 July 2016, (Wrocław University).


References


Further reading

*Tomasz Cieszyński
O PROFESORZE JAKUBIE PARNASIE NA TLE LWOWA z lat 1938 do 1945
(see bottom of the article for English summary) *Tadeusz Korzybski, ''Słownik biologów polskich'', Warszawa 1987


External links


Barańska J ''et al''. (2007) Jakub Karol Parnas – life and creativity (Opening Lecture), 6th Parnas Conference Molecular Mechanism of Cellular Signalling (Kraków, Poland, 30 May – 2 June 2007) ''Acta Biochimica Polonica'' 54 (Suppl. 2), 1
{{DEFAULTSORT:Parnas, Jakob Karol 1884 births 1949 deaths People from Lviv Oblast Ukrainian Jews Ukrainian biochemists Jewish scientists Jews from Galicia (Eastern Europe) Polish people who died in Soviet detention Soviet biochemists