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Julius Caesar Aranzi (Giulio Cesare Aranzio, Arantius) (1529/1530 – April 7, 1589) was a leading figure in the history of the science of
human anatomy The human body is the structure of a human being. It is composed of many different types of cells that together create tissues and subsequently organ systems. They ensure homeostasis and the viability of the human body. It comprises a he ...
. He was born in
Bologna Bologna (, , ; egl, label= Emilian, Bulåggna ; lat, Bononia) is the capital and largest city of the Emilia-Romagna region in Northern Italy. It is the seventh most populous city in Italy with about 400,000 inhabitants and 150 different nat ...
, the son of Ottaviano di Jacopo and Maria Maggi. Owing to the poverty of the family, he studied with his uncle Bartolomeo Maggi (1477–1552), a famous surgeon who was a lecturer at the
University of Bologna The University of Bologna ( it, Alma Mater Studiorum – Università di Bologna, UNIBO) is a public research university in Bologna, Italy. Founded in 1088 by an organised guild of students (''studiorum''), it is the oldest university in continuo ...
as well as court physician to
Julius III Pope Julius III ( la, Iulius PP. III; it, Giulio III; 10 September 1487 – 23 March 1555), born Giovanni Maria Ciocchi del Monte, was head of the Catholic Church and ruler of the Papal States from 7 February 1550 to his death in March 155 ...
. He held this uncle in such high esteem that he assumed his surname, calling himself Giulio Cesare Aranzio Maggio. He was admitted to the
University of Padua The University of Padua ( it, Università degli Studi di Padova, UNIPD) is an Italian university located in the city of Padua, region of Veneto, northern Italy. The University of Padua was founded in 1222 by a group of students and teachers from B ...
, where he made his first discovery in 1548, at the age of nineteen, when he described the elevator muscle of the upper eyelid. Later, at the University of Bologna, he received a doctorate in medicine in 1556 and was appointed a lecturer in medicine and surgery shortly thereafter at the age of twenty-seven. In 1570, surgery and anatomy were separated into separate professorships at his instigation and he held the newly created chair in anatomy for thirty-three years until his death at Bologna in 1589. From Aranzio came the first correct account of the anatomical peculiarities of the
fetus A fetus or foetus (; plural fetuses, feti, foetuses, or foeti) is the unborn offspring that develops from an animal embryo. Following embryonic development the fetal stage of development takes place. In human prenatal development, fetal deve ...
, and he was the first to show that the
muscle Skeletal muscles (commonly referred to as muscles) are organs of the vertebrate muscular system and typically are attached by tendons to bones of a skeleton. The muscle cells of skeletal muscles are much longer than in the other types of muscl ...
s of the
eye Eyes are organs of the visual system. They provide living organisms with vision, the ability to receive and process visual detail, as well as enabling several photo response functions that are independent of vision. Eyes detect light and conv ...
do not, as was previously imagined, arise from the
dura mater In neuroanatomy, dura mater is a thick membrane made of dense irregular connective tissue that surrounds the brain and spinal cord. It is the outermost of the three layers of membrane called the meninges that protect the central nervous system. ...
but from the margin of the optic hole. He also, after considering the anatomical relations of the cavities of the
heart The heart is a muscular organ in most animals. This organ pumps blood through the blood vessels of the circulatory system. The pumped blood carries oxygen and nutrients to the body, while carrying metabolic waste such as carbon dioxide t ...
, the
valve A valve is a device or natural object that regulates, directs or controls the flow of a fluid (gases, liquids, fluidized solids, or slurries) by opening, closing, or partially obstructing various passageways. Valves are technically fittings ...
s and the great vessels, corroborated the views of
Realdo Colombo Matteo Realdo Colombo (c. 1515 – 1559) was an Italian professor of anatomy and a surgeon at the University of Padua between 1544 and 1559. Early life and education Matteo Realdo Colombo or Realdus Columbus, was born in Cremona, Lombardy, the ...
regarding the course which the blood follows in passing from the right to the left side of the heart. Aranzio was the first anatomist to describe distinctly the inferior cornua of the ventricles of the
cerebrum The cerebrum, telencephalon or endbrain is the largest part of the brain containing the cerebral cortex (of the two cerebral hemispheres), as well as several subcortical structures, including the hippocampus, basal ganglia, and olfactory bulb. In ...
, who recognizes the objects by which they are distinguished, and who gives them the name by which they are still known (
hippocampus The hippocampus (via Latin from Greek , 'seahorse') is a major component of the brain of humans and other vertebrates. Humans and other mammals have two hippocampi, one in each side of the brain. The hippocampus is part of the limbic system, a ...
) in 1564; and his account is more minute and perspicuous than that of the authors of the subsequent century. He speaks at length of the
choroid plexus The choroid plexus, or plica choroidea, is a plexus of cells that arises from the tela choroidea in each of the ventricles of the brain. Regions of the choroid plexus produce and secrete most of the cerebrospinal fluid (CSF) of the central nerv ...
, and gives a detailed description of the fourth ventricle, under the name of '' cistern of the cerebellum'', as a discovery of his own. He also was the first to discover that the blood of mother and fetus remain separate during pregnancy. As a professor of anatomy and surgery at the University of Bologna from 1556, he established anatomy as a major branch of medicine for the first time. Aranzi combined anatomy with a description of pathological processes, based largely on his own research, Galen, and the work of his contemporary Italians. Aranzi discovered the 'Nodules of Aranzio' in the semilunar valves of the heart and wrote the first description of the superior levator palpebral and the coracobrachialis muscles. His books (in Latin) covered surgical techniques for many conditions, including hydrocephalus, nasal polyp, goitre and tumours to phimosis, ascites, haemorrhoids, anal abscess and fistulae.Raffi Gurunluoglu et al. "Giulio Cesare Aranzio (Arantius) (1530–1589) in the pageant of anatomy and surgery," ''Journal of Medical Biography'' (2011) 19#2 pp. 63–69


Bibliography

*''De humano foetu opusculum'', Rome, 1564; Venice, 1571; Basel, 1579. 32: De formato foetu. Bononiae, J. Rubrius, 1564. *''De tumoribus secundum locus affectum''. Bologna, 1571. *''In Hippocrates librum de vulneribus capitis''. Leiden, 1580. *''Observationes anatomicae''. Basel, 1579; Venice 1587. These works were published together in Venice in 1587: *''De tumoribus prater naturam secundum locos affectus liber''. *''De humano foetu liber''. *''Anatomicarum observationum liber''.


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Who Named It?
{{DEFAULTSORT:Aranzi, Julius Caesar 1530 births 1589 deaths 16th-century Italian physicians 16th-century Latin-language writers Italian anatomists Italian neuroscientists History of neuroscience University of Bologna alumni University of Padua alumni Physicians from Bologna