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"Joy to the World" is the eleventh episode of the fifth season of ''
House A house is a single-unit residential building. It may range in complexity from a rudimentary hut to a complex structure of wood, masonry, concrete or other material, outfitted with plumbing, electrical, and heating, ventilation, and air condi ...
'' and the ninety-seventh episode overall. It aired on December 9, 2008.


Plot

A troubled sixteen-year-old, Natalie, is singing at her school's Christmas program when she suddenly becomes disoriented and vomits. She is brought to
Princeton-Plainsboro Teaching Hospital ''House'' (also called ''House, M.D.'') is an American medical drama television series that originally ran on the Fox network for eight seasons, from November 16, 2004, to May 21, 2012. The series' main character is Dr. Gregory House (Hugh ...
, where the team discovers her
liver The liver is a major Organ (anatomy), organ only found in vertebrates which performs many essential biological functions such as detoxification of the organism, and the Protein biosynthesis, synthesis of proteins and biochemicals necessary for ...
is failing for an unknown reason. In House's office, the team exchange Christmas gifts when House receives a mysterious gift. The present turns out to be Dr. Joseph Bell's ''Manual of The Operations of Surgery''. House, annoyed, throws it in the trash. Afterwards, House conducts a
differential diagnosis In healthcare, a differential diagnosis (abbreviated DDx) is a method of analysis of a patient's history and physical examination to arrive at the correct diagnosis. It involves distinguishing a particular disease or condition from others that p ...
, with the team entertaining ideas such as
alcohol abuse Alcohol abuse encompasses a spectrum of unhealthy alcohol drinking behaviors, ranging from binge drinking to alcohol dependence, in extreme cases resulting in health problems for individuals and large scale social problems such as alcohol-relat ...
and pill-popping, but none of the symptoms fit the entire picture. When Chase and Kutner question Natalie's classmates, one admits they slipped "
magic mushrooms Psilocybin mushrooms, commonly known as magic mushrooms, are a polyphyletic informal group of fungi that contain psilocybin which turns into psilocin upon ingestion. Biological genera containing psilocybin mushrooms include ''Psilocybe'', ''Pa ...
" into her food. Meanwhile, Foreman and Thirteen are still involved in the
Huntington's Huntington's disease (HD), also known as Huntington's chorea, is a neurodegenerative disease that is mostly inherited. The earliest symptoms are often subtle problems with mood or mental abilities. A general lack of coordination and an unst ...
drug trial. A woman whose disease is quite advanced drops out of the trial, saying that Foreman told her to "get over it" when her medication made her nauseous. Thirteen, annoyed, accuses Foreman of being like House. After briefly suggesting the gift was from a former patient and old flame
Irene Adler Irene Adler is a fictional character in the Sherlock Holmes stories written by Sir Arthur Conan Doyle. A former opera singer and actress, she was featured in the short story " A Scandal in Bohemia", published in July 1891. Adler is one of the ...
, Wilson tells the team that it is in fact last year's gift from Wilson himself, which House never opened. Wilson accuses House of needing to create the false illusion of a gift because he just cannot be nice to anyone. They bet that House cannot get thanked by a patient. Later, after Natalie's tox-screen was clean, Taub and Kutner find
Tylenol Tylenol may refer to: * Paracetamol (acetaminophen), a medication used to treat pain and fever * Tylenol (brand) Tylenol () is a brand of medication, advertised for reducing pain, reducing fever, and relieving the symptoms of allergies, cold, ...
in her school locker, which makes them think she tried to kill herself by acetaminophen toxicity. They later suspect
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
, thinking she might have picked up something from the soup kitchen she normally attends. To win the bet with Wilson, House behaves kindly and caring toward his patients. A naive woman, Whitney, comes to the clinic with a terrible headache and compliments House on his hospitality, to which he responds, "If you can't be nice, why be a doctor?" He later deduces she is pregnant, much to her surprise. She insists that she and her fiancé are virgins, and asks for a
paternity test DNA paternity testing is the use of DNA profiles to determine whether an individual is the biological parent of another individual. Paternity testing can be especially important when the rights and duties of the father are in issue and a child ...
when House suggests that she has had an affair. After sharing the test results with them, he looks surprised, and leaves to repeat the test. He returns with the same results, and with a look of disbelief, states that Whitney is pregnant as a result of human parthenogenesis, a never-seen-before phenomenon. Her baby only has maternal genes due to a spontaneous gene mutation which fertilized her egg, without ever needing male sperm. Her baby will be a virgin birth. Later, however, it is revealed that House faked the results and told them the story to cover up Whitney's infidelity, thereby 'saving' their relationship but saddling the fiancé with a cheating potential future wife and another man's child. Things make a turn for the worse for Natalie, as she has a
seizure An epileptic seizure, informally known as a seizure, is a period of symptoms due to abnormally excessive or synchronous neuronal activity in the brain. Outward effects vary from uncontrolled shaking movements involving much of the body with los ...
, ruling out TB but bringing her brain into the differential, along with the liver and
lungs The lungs are the primary organs of the respiratory system in humans and most other animals, including some snails and a small number of fish. In mammals and most other vertebrates, two lungs are located near the backbone on either side of th ...
. Kutner suggests a
mold A mold () or mould () is one of the structures certain fungus, fungi can form. The dust-like, colored appearance of molds is due to the formation of Spore#Fungi, spores containing Secondary metabolite#Fungal secondary metabolites, fungal seco ...
allergy Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic derma ...
, for which the team test her. Natalie admits to buying alcohol from her friend Simon, whom Kutner and Taub question. Taub suggests alcohol poisoning, but it turns out that she hardly drank any of the alcohol and had only bought it to impress Simon. She goes into
cardiac arrest Cardiac arrest is when the heart suddenly and unexpectedly stops beating. It is a medical emergency that, without immediate medical intervention, will result in sudden cardiac death within minutes. Cardiopulmonary resuscitation (CPR) and possib ...
, ruling out the alcohol theory. But her high blood
alkaline phosphatase The enzyme alkaline phosphatase (EC 3.1.3.1, alkaline phosphomonoesterase; phosphomonoesterase; glycerophosphatase; alkaline phosphohydrolase; alkaline phenyl phosphatase; orthophosphoric-monoester phosphohydrolase (alkaline optimum), systematic ...
level nonetheless suggests
leukemia Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ' ...
, and Wilson is brought in to help. While Cuddy desperately tries to rule leukemia out, Wilson discusses its likelihood and says that she will die, even if they kill all the cancer, due to her failing heart and liver. A double transplant would not even save her. Cuddy then has an epiphany after talking with House about the pregnant couple and gravely realizes the only other disease that explains everything: post-partum
eclampsia Eclampsia is the onset of seizures (convulsions) in a woman with pre-eclampsia. Pre-eclampsia is one of the hypertensive disorders of pregnancy that presents with three main features: new onset of high blood pressure, large amounts of protein in ...
, which means that Natalie must have got pregnant and had a child. This turns out to be correct, and her friend Simon is the unknowing father. Natalie explains that she gave birth in an abandoned house but her daughter was
stillborn Stillbirth is typically defined as fetal death at or after 20 or 28 weeks of pregnancy, depending on the source. It results in a baby born without signs of life. A stillbirth can result in the feeling of guilt or grief in the mother. The term i ...
. Cuddy searches the house and finds the baby girl, alive, being cared for by a pair of homeless squatters, and brings the baby back to the hospital where she reunites her with her mother. Unfortunately, due to the extent of Natalie's failing organs, she will die within hours (although this is not shown in the episode). The baby is in good health but is kept for observation as she is premature. In the end, the whole team is full of Christmas spirit. Kutner finds a former classmate he used to bully and apologizes to him. During the episode he is shown to be furious about Natalie being bullied and when asked says that he was never bullied. Cuddy plans to become a foster parent and adopt the baby, as neither grandparent wants to care for her as she will recall memories too painful for them to handle, with House wishing her "Merry Christmas, Cuddy." Thirteen tells Foreman that he is not like House, after he welcomed back the woman who dropped out of the trial and is taking better care of her. Foreman and Thirteen passionately kiss.


External links


"Joy to the World"
at
Fox.com The Fox Broadcasting Company, commonly known simply as Fox and stylized in all caps as FOX, is an American commercial broadcast television network owned by Fox Corporation and headquartered in New York City, with master control operations and ...
* {{DEFAULTSORT:Joy To The World House (season 5) episodes American Christmas television episodes 2008 American television episodes Television episodes about bullying Television episodes directed by David Straiton fr:Saison 5 de Dr House#Épisode 11 : Le Divin Enfant