Joseph M. DeSimone
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Joseph M. DeSimone (born May 16, 1964) is an American
chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe th ...
, inventor, and entrepreneur who has co-founded companies based on his research, including the American
3D printing 3D printing or additive manufacturing is the Manufacturing, construction of a three-dimensional object from a computer-aided design, CAD model or a digital 3D modeling, 3D model. It can be done in a variety of processes in which material is ...
technology company,
Carbon Carbon () is a chemical element with the symbol C and atomic number 6. It is nonmetallic and tetravalent In chemistry, the valence (US spelling) or valency (British spelling) of an element is the measure of its combining capacity with o ...
, of which he was
CEO A chief executive officer (CEO), also known as a central executive officer (CEO), chief administrator officer (CAO) or just chief executive (CE), is one of a number of corporate executives charged with the management of an organization especially ...
from 2014 until November 2019. Currently, DeSimone is the Sanjiv Sam Gambhir Professor of Translational Medicine in the Department of Radiology at
Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is consider ...
, where he is also Professor of Chemical Engineering. He joined the faculty at Stanford in 2020. In 2020, he was also elected to the board of trustees of the
National Geographic Society The National Geographic Society (NGS), headquartered in Washington, D.C., United States, is one of the largest non-profit scientific and educational organizations in the world. Founded in 1888, its interests include geography, archaeology, and ...
. DeSimone previously held a joint appointment as the Chancellor's Eminent Professor of Chemistry at the
University of North Carolina at Chapel Hill A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States ...
and
William R. Kenan Jr. William Rand Kenan Jr. (April 30, 1872 – July 28, 1965) was an American chemist, engineer, manufacturer, dairy farmer, and philanthropist. Early life William Rand Kenan Jr. was born in Wilmington, North Carolina, on April 30, 1872., son of Willi ...
Distinguished Professor of Chemical Engineering at
North Carolina State University North Carolina State University (NC State) is a public land-grant research university in Raleigh, North Carolina. Founded in 1887 and part of the University of North Carolina system, it is the largest university in the Carolinas. The universit ...
. DeSimone has published over 350 scientific articles and has over 200 issued patents in his name with over 200 patents pending. He was awarded the 2020
Harvey Prize Harvey Prize is an annual Israeli award for breakthroughs in science and technology, as well as contributions to peace in the Middle East granted by the Technion in Haifa. History The prize is named for industrialist and inventor Leo Harvey. T ...
for "significant contributions to materials science, chemistry, polymer science nano medicine, and 3D printing".


Education

DeSimone received his BS in Chemistry in 1986 from
Ursinus College Ursinus College is a private liberal arts college in Collegeville, Pennsylvania. It was founded in 1869 and occupies a 170-acre campus. History 19th century In 1867, members of the German Reformed Church began plans to establish a college w ...
in
Collegeville, Pennsylvania Collegeville is a borough in Montgomery County, Pennsylvania, a suburb outside of Philadelphia on Perkiomen Creek. Collegeville was incorporated in 1896. It is the location of Ursinus College which opened in 1869. The population was 5,089 at t ...
and his PhD in Chemistry in 1990 from
Virginia Tech Virginia Tech (formally the Virginia Polytechnic Institute and State University and informally VT, or VPI) is a Public university, public Land-grant college, land-grant research university with its main campus in Blacksburg, Virginia. It also ...
in
Blacksburg, Virginia Blacksburg is an incorporated town in Montgomery County, Virginia, United States, with a population of 44,826 at the 2020 census. Blacksburg, as well as the surrounding county, is dominated economically and demographically by the presence of V ...
.


Career

DeSimone is a member of the
National Academy of Medicine The National Academy of Medicine (NAM), formerly called the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, En ...
(2014),
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
(2012), and the
National Academy of Engineering The National Academy of Engineering (NAE) is an American nonprofit, non-governmental organization. The National Academy of Engineering is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy ...
(2005). He is also a member of the
American Academy of Arts and Sciences The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and ...
(2005). In the 1990s, at the
University of North Carolina at Chapel Hill A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States ...
, he developed an environmentally friendly manufacturing process that relies on
supercritical carbon dioxide Supercritical carbon dioxide (s) is a fluid state of carbon dioxide where it is held at or above its critical temperature and critical pressure. Carbon dioxide usually behaves as a gas in air at standard temperature and pressure (STP), or as ...
instead of water and bio-persistent
surfactant Surfactants are chemical compounds that decrease the surface tension between two liquids, between a gas and a liquid, or interfacial tension between a liquid and a solid. Surfactants may act as detergents, wetting agents, emulsifiers, foaming ...
s for the creation of
fluoropolymer A fluoropolymer is a fluorocarbon-based polymer with multiple carbon–fluorine bonds. It is characterized by a high resistance to solvents, acids, and bases. The best known fluoropolymer is polytetrafluoroethylene under the brand name "Teflon ...
s or
high-performance plastics High-performance plastics are plastics that meet higher requirements than ''standard'' or ''engineering'' plastics. They are more expensive and used in smaller amounts. Definition High performance plastics differ from standard plastics and eng ...
, such as
Teflon Polytetrafluoroethylene (PTFE) is a synthetic fluoropolymer of tetrafluoroethylene that has numerous applications. It is one of the best-known and widely applied PFAS. The commonly known brand name of PTFE-based composition is Teflon by Chemou ...
. In 2002 DeSimone, along with Richard Stack, a cardiologist at
Duke University Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James ...
, co-founded Bioabsorbable Vascular Solutions (BVS) to commercialize a fully bioabsorbable, drug-eluting
stent In medicine, a stent is a metal or plastic tube inserted into the lumen of an anatomic vessel or duct to keep the passageway open, and stenting is the placement of a stent. A wide variety of stents are used for different purposes, from expandab ...
for the treatment of
coronary artery disease Coronary artery disease (CAD), also called coronary heart disease (CHD), ischemic heart disease (IHD), myocardial ischemia, or simply heart disease, involves the reduction of blood flow to the heart muscle due to build-up of atherosclerotic pla ...
. BVS was acquired by
Guidant Guidant Corporation, part of Boston Scientific and Abbott Labs, designs and manufactures artificial cardiac pacemakers, implantable cardioverter-defibrillators, stents, and other cardiovascular medical products. Their company headquarters is loc ...
in 2003. As a professor at the
University of North Carolina at Chapel Hill A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States ...
and
North Carolina State University North Carolina State University (NC State) is a public land-grant research university in Raleigh, North Carolina. Founded in 1887 and part of the University of North Carolina system, it is the largest university in the Carolinas. The universit ...
, DeSimone and members of his academic laboratory also developed the nanoparticle fabrication technology, PRINT (Particle Replication in Non-Wetting Templates), leading DeSimone and students to co-found the company
Liquidia Technologies
in 2004. Liquidia develops PRINT particle-based medical treatments and became a publicly traded company in 2018. At the University of North Carolina at Chapel Hill, the PRINT technology also became a foundation for the Carolina Center for Cancer Nanotechnology Excellence funded by the
National Cancer Institute The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. ...
. In 2015, DeSimone and colleagues published a paper in ''
Science Magazine ''Science'', also widely referred to as ''Science Magazine'', is the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals. It was first published in 1880, ...
'' on their invention of a rapid polymer 3D printing technology, Continuous Liquid Interface Production (CLIP). The company,
Carbon Carbon () is a chemical element with the symbol C and atomic number 6. It is nonmetallic and tetravalent In chemistry, the valence (US spelling) or valency (British spelling) of an element is the measure of its combining capacity with o ...
, which DeSimone co-founded, now develops printers with the CLIP technology. The printers are used to make end-use parts and products in several industries, including by the companies
Adidas Adidas AG (; stylized as adidas since 1949) is a German multinational corporation, founded and headquartered in Herzogenaurach, Bavaria, that designs and manufactures shoes, clothing and accessories. It is the largest sportswear manufactur ...
, Resolution Medical, and
Ford Ford commonly refers to: * Ford Motor Company, an automobile manufacturer founded by Henry Ford * Ford (crossing), a shallow crossing on a river Ford may also refer to: Ford Motor Company * Henry Ford, founder of the Ford Motor Company * Ford F ...
. Recently, DeSimone has also been involved in the digital fabrication space using computational design to speed up the former method.


Awards and honors

DeSimone is the recipient of the 2000 Oliver Max Gardner Award from the University of North Carolina; the 2002 Engineering Excellence Award by DuPont; the 2002 Wallace H. Carothers Award from the Delaware Section of the
American Chemical Society The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all d ...
; the 2002
John Scott Award John Scott Award, created in 1816 as the John Scott Legacy Medal and Premium, is presented to men and women whose inventions improved the "comfort, welfare, and happiness of human kind" in a significant way. "...the John Scott Medal Fund, establish ...
presented by the Board of Directors of City Trusts, Philadelphia, given to "the most deserving" men and women whose inventions have contributed in some outstanding way to the "comfort, welfare and happiness" of mankind; the 2005 American Chemical Society Award for Creative Invention; the 2007 Collaboration Success Award from the
Council for Chemical Research Council for Chemical Research is an organization based in Washington, DC, whose membership represents the U.S. chemical research enterprise. CCR was formed in 1979 to promote cooperation in basic research and encourage high-quality education in th ...
; the 2008
Lemelson–MIT Prize The Lemelson-MIT Program awards several prizes yearly to inventors in the United States. The largest is the Lemelson–MIT Prize which was endowed in 1994 by Jerome H. Lemelson, funded by the Lemelson Foundation, and is administered through the Sc ...
, the 2009
North Carolina Award The North Carolina Award is the highest civilian award bestowed by the U.S. state of North Carolina. It is awarded in the four fields of science, literature, the fine arts, and public service. Sometimes referred to as the "Nobel Prize of North Carol ...
; the 2009
NIH Director's Pioneer Award National Institutes of Health Director's Pioneer Award is a research initiative first announced in 2004 designed to support individual scientists' biomedical research. The focus is specifically on "pioneering" research that is highly innovative ...
; the 2010 AAAS Mentor Award in recognition of his efforts to advance diversity in the chemistry PhD workforce; the 2012 Walston Chubb Award for Innovation; the 2014 American Chemical Societ
Kathryn C. Hach Award for Entrepreneurial Success
the 2014 Dickson Prize in Science; the 2014
IRI Medal The IRI Medal, established by the Industrial Research Institute (IRI) in 1946, recognizes and honors leaders of technology for their outstanding accomplishments in technological innovation which contribute broadly to the development of industry and ...
; and the 2015 Kabiller Prize in Nanoscience and Nanomedicine. DeSimone was awarded the
National Medal of Technology and Innovation The National Medal of Technology and Innovation (formerly the National Medal of Technology) is an honor granted by the President of the United States to American inventors and innovators who have made significant contributions to the development ...
, the highest honor in the U.S. for achievements related to technological progress, by
President President most commonly refers to: *President (corporate title) *President (education), a leader of a college or university *President (government title) President may also refer to: Automobiles * Nissan President, a 1966–2010 Japanese ful ...
Barack Obama Barack Hussein Obama II ( ; born August 4, 1961) is an American politician who served as the 44th president of the United States from 2009 to 2017. A member of the Democratic Party, Obama was the first African-American president of the U ...
at the White House in May 2016. In 2017, Dr. DeSimone received the 22nd Annual
Heinz Award The Heinz Awards are individual achievement honors given annually by the Heinz Family Foundation. The Heinz Awards each year recognize outstanding individuals for their innovative contributions in three areas: the Arts, the Economy and the Enviro ...
in Technology, the Economy, and Employment. In 2019, DeSimone received the
Wilhelm Exner Medal The Wilhelm Exner Medal has been awarded by the Austrian Industry Association, (ÖGV), for excellence in research and science since 1921. The medal is dedicated to Wilhelm Exner (1840–1931), former president of the Association, who initialized ...
in ''Polymer Manufacturing''. Also in 2019, he was named the U.S. Entrepreneur Of The Year, National Overall Award winner by
Ernst & Young Ernst & Young Global Limited, trade name EY, is a multinational professional services partnership headquartered in London, England. EY is one of the largest professional services networks in the world. Along with Deloitte, KPMG and Pricewaterh ...
. For the years 2019-2020 he was awarded the
Harvey Prize Harvey Prize is an annual Israeli award for breakthroughs in science and technology, as well as contributions to peace in the Middle East granted by the Technion in Haifa. History The prize is named for industrialist and inventor Leo Harvey. T ...
of the Technion in Israel. In 2021, he received the
Charles Goodyear Medal The Charles Goodyear Medal is the highest honor conferred by the American Chemical Society, Rubber Division. Established in 1941, the award is named after Charles Goodyear, the discoverer of vulcanization, and consists of a gold medal, a framed c ...
from the
American Chemical Society The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all d ...
Rubber Division. DeSimone was elected a member of the
National Academy of Engineering The National Academy of Engineering (NAE) is an American nonprofit, non-governmental organization. The National Academy of Engineering is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy ...
(2005) for the development of environmentally friendly chemistries and processes for the synthesis of materials, especially new fluoropolymers.


References


External links


Oral history interview transcript with Joseph DeSimone on 24 May 2021, American Institute of Physics, Niels Bohr Library & Archives
{{DEFAULTSORT:Desimone, Joseph 1964 births Living people American chemical engineers American chemical industry businesspeople Fellows of the American Academy of Arts and Sciences Lemelson–MIT Prize Members of the United States National Academy of Engineering Members of the United States National Academy of Sciences Ursinus College alumni Fellows of the American Institute for Medical and Biological Engineering Virginia Tech alumni Members of the National Academy of Medicine