Jonathan J. Lewis is an American surgeon, biomedical researcher and entrepreneur. He was trained in surgery in South Africa, Britain, and the United States, and is a fellow of both the

Royal College of Surgeons The Royal College of Surgeons is an ancient college (a form of corporation) established in England to regulate the activity of surgeons. Derivative organisations survive in many present and former members of the Commonwealth. These organisations a ...

and the

American College of Surgeons The American College of Surgeons is an educational association of surgeons created in 1913.American College of Surgeons Online "What is the American College of Surgeons?"/ref> See also *American College of Physicians The American College o ...

. Dr. Lewis was awarded an MB.B.Ch. from

University of the Witwatersrand The University of the Witwatersrand, Johannesburg (), is a multi-campus South African Public university, public research university situated in the northern areas of central Johannesburg. It is more commonly known as Wits University or Wits ( o ...

School of Medicine, and his Ph.D. in Molecular Biology from Witwatersrand and

Yale School of Medicine The Yale School of Medicine is the graduate medical school at Yale University, a private research university in New Haven, Connecticut. It was founded in 1810 as the Medical Institution of Yale College and formally opened in 1813. The primary te ...

. He completed his Surgical Residency at

Charlotte Maxeke Johannesburg Academic Hospital The Charlotte Maxeke Johannesburg Academic Hospital is an accredited general hospital in Parktown, Johannesburg, Gauteng, South Africa. Size and capability The main structure was opened in 1979. The facility has 1,088 usable beds. The hospital's ...

and at

Yale-New Haven Hospital Yale New Haven Hospital (YNHH) is a 1,541-bed hospital located in New Haven, Connecticut. It is owned and operated by the Yale New Haven Health System. YNHH includes the 168-bed Smilow Cancer Hospital at Yale New Haven, the 201-bed Yale New Have ...

. Lewis was a Professor of Surgery and Medicine Memorial Sloan-Kettering Cancer Center, before working in the

biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...

and healthcare industries, serving in several CEO and Chairman roles. He is currently chairman and co-founder of the Molecular Ninja Group and chairman and co-founder o
Dugri Inc

Education

Lewis received his MB. B.Ch. from

in 1982 and his Ph.D. degree in the Molecular and Cell Biology of Growth Factor Signal Transduction from the University of Witwatersrand and

in 1990. He was elected a fellow of the Royal College of Surgeons in 1987. At Yale he trained with Elton Cahow and William Collins, and at Memorial Sloan-Kettering Cancer Center he trained with Sir

Murray Brennan Sir Murray Frederick Brennan (born 2 April 1940) is a New Zealand surgeon, oncologist, cancer researcher, and academic. From 1985 to 2006, he was chairman of the surgery department of the Memorial Sloan Kettering Cancer Center in New York City, ...

. At Sloan-Kettering, he completed postdoctoral research in the immunology lab of Alan Houghton.

Research and scientific contribution

Lewis’ research has contributed to the development of innovative cancer treatments and treatment approaches. Lewis' work focused on better understanding the biology and treatment of difficult-to-treat cancers. This includes the early use of peptides and DNA vaccines with active immunotherapy using T cells, a better understanding of the biology and role of surgery in retroperitoneal sarcoma, the liberal and correct use of re-resection in extremity sarcoma, and the potential use of vaccines in

pancreatic cancer Pancreatic cancer arises when cell (biology), cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a Neoplasm, mass. These cancerous cells have the malignant, ability to invade other parts of t ...

. Lewis has authored over 200 scientific publications, which include work in the biology and treatment of

sarcoma A sarcoma is a malignant tumor, a type of cancer that arises from transformed cells of mesenchymal (connective tissue) origin. Connective tissue is a broad term that includes bone, cartilage, fat, vascular, or hematopoietic tissues, and sarcom ...

, the biology and treatment of

, molecular cancer vaccines,

gene therapy Gene therapy is a medical field which focuses on the genetic modification of cells to produce a therapeutic effect or the treatment of disease by repairing or reconstructing defective genetic material. The first attempt at modifying human DN ...

and the translation of laboratory findings to the clinic, in addition to writing chapters or sections in 15 textbooks. Lewis has worked with Yotam Dagan, Sir

and others to help hone the development of next-generation technology platforms for scale in the management of operational stress management and PTSD. During his career as a physician, Lewis cared for

Kitch Christie George Moir Christie, better known as Kitch Christie (31 January 1940 – 22 April 1998), was a South African rugby union coach best known for coaching the country's national team, the Springboks, to victory at the 1995 Rugby World Cup. He remai ...

, the head coach of the 1995 South Africa national rugby union team, Chief Justice

Ismail Mahomed Ismail Mahomed SCOB SC (5 July 1931 – 17 June 2000) was a South African lawyer who served as the Chief Justice of South Africa and the Chief Justice of Namibia, and co-authored the constitution of Namibia. Early life Mahomed was born in Pr ...

, and

Kate McGarrigle Kate McGarrigle (February 6, 1946 – January 18, 2010)Obituary at CBC ...

. He has served on multiple boards of non-profits, including as chairman of the board of trustees and Scientific Advisory Council of the Hope Funds for Cancer Research and as an Honorary Member of the Board of Directors of the Sarcoma Foundation of America.

References

{{DEFAULTSORT:Lewis, Jonathan 1959 births Living people Yale School of Medicine alumni Yale School of Medicine faculty American surgeons People from Fairfield County, Connecticut People from Johannesburg Businesspeople from New Haven, Connecticut Fellows of the Royal College of Surgeons of England