Jonathan "Joe" Betts-LaCroix (born Jonathan Betts February 26, 1962) is an American
scientist
A scientist is a person who conducts scientific research to advance knowledge in an area of the natural sciences.
In classical antiquity, there was no real ancient analog of a modern scientist. Instead, philosophers engaged in the philosoph ...
and
entrepreneur
Entrepreneurship is the creation or extraction of economic value. With this definition, entrepreneurship is viewed as change, generally entailing risk beyond what is normally encountered in starting a business, which may include other values t ...
known for his discoveries in
biophysics
Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. ...
and for creating the world's smallest
personal computer
A personal computer (PC) is a multi-purpose microcomputer whose size, capabilities, and price make it feasible for individual use. Personal computers are intended to be operated directly by an end user, rather than by a computer expert or tec ...
. He is working to optimize medical research priorities in the U.S.
Academics
Beginning in earth sciences at Harvard, Betts-LaCroix contributed to the field of long-term regulation of oxygen on Earth over multi-100 Million-year timespans, quantifying the effect of the burial efficiency of organic carbon as a feedback mechanism.
At MIT, he designed and built an autonomous, robotic system that enables research into ocean circulation patterns and climate change, by operating untended for up to one year at sea on battery power and collecting hyper-pure water samples at predetermined intervals.
In work at Caltech, Betts-LaCroix moved into biophysics, publishing a paper in ''
Science
Science is a systematic endeavor that Scientific method, builds and organizes knowledge in the form of Testability, testable explanations and predictions about the universe.
Science may be as old as the human species, and some of the earli ...
'' that has been cited by more than 700 subsequent scientific works.
In this work, he, along with
David Beratan
David Nathan Beratan (born 1958) is an American chemist and physicist, the R.J. Reynolds Professor of Chemistry at Duke University. He has secondary appointments in the departments of Physics and Biochemistry. He is the Director of the Center ...
and
José Onuchic José Nelson Onuchic is a Brazilian and American physicist, the Harry C & Olga K Wiess Professor of Physics at Rice University.[OQO
OQO was a U.S. computer hardware company that was notable for manufacture of handheld computers. Its systems possessed the functionality of a tablet computer, tablet PC in a size slightly larger than a personal digital assistant (PDA). According t ...](_blank)
, a computer hardware and software OEM credited by the Guinness World Records as having created the world's smallest Windows PC.
[Guinness Book of World Records 2006, ] This created a new category of mobile computing devices between PDAs and laptops, which were initially dubbed the "Ultra Personal Computer", and which subsequently became known as the "Netbook". The device won many awards for its innovation, aesthetics and functionality.
After OQO, Betts-Lacroix was active in Silicon Valley as a lecturer and mentor for CEOs of start up companies.
Biotechnology & biomedicine
Betts-LaCroix has participated in the Quantified Self movement since the beginning,
and has given numerous presentations on aspects of self experimentation and tracking, including experiments in the 28-Hour day.
In 2010 he joined startup Halcyon Molecular to lead its automation efforts.
Halcyon, funded by, among others,
Elon Musk
Elon Reeve Musk ( ; born June 28, 1971) is a business magnate and investor. He is the founder, CEO and chief engineer of SpaceX; angel investor, CEO and product architect of Tesla, Inc.; owner and CEO of Twitter, Inc.; founder of The ...
and
Peter Thiel
Peter Andreas Thiel (; born 11 October 1967) is a German-American billionaire entrepreneur, venture capitalist, and political activist. A co-founder of PayPal, Palantir Technologies, and Founders Fund, he was the first outside investor in F ...
, attempted to sequence human
DNA using
electron microscopes
An electron microscope is a microscope that uses a beam of accelerated electrons as a source of illumination. As the wavelength of an electron can be up to 100,000 times shorter than that of visible light photons, electron microscopes have a hi ...
. The underlying goal of Halcyon's work was to make meaningful progress in understanding human biology in order to improve medicine.
Following the theme of improving medicine, Betts-LaCroix founded th
Health Extension Foundationin 2012.
The efforts of the people working in Health Extension are motivated by recognizing that
#Most healthcare money treats age-related diseases;
#Aging is the single biggest risk factor for these diseases;
#But funding to address the biochemical processes of aging is less than 0.01% of healthcare spending—and correcting this missed opportunity to optimally assign medical research and translation priorities.
In 2013 Betts-LaCroix cofounded Vium, which has raised $33M to accelerate the development of new medical therapies by automating in-vivo research.
Vium launched publicly in 2016,
and was later acquired by Recursion in 2020.
Betts-LaCroix is also a biotech angel investor in such companies as
StemCentrx, Recursion Pharma
and Spring Discovery,
as well as a part-time contributor at
Y Combinator
Y Combinator (YC) is an American technology startup accelerator launched in March 2005. It has been used to launch more than 3,000 companies, including Airbnb, Coinbase, Cruise, DoorDash, Dropbox, Instacart, Quora, PagerDuty, Reddit, St ...
.
In 2022 Betts-LaCroix cofounded Retro Biosciences, which emerged out of stealth with $180 million in funding to focus on extending healthy human lifespans.
See also
*
Aging-associated diseases
References
External links
Health Extension"Joe Betts-LaCroix at TEDxSF 2011"
* Goethe Institute
"Transience and Permanence"* Oakland Futurist
"Health Extension Salon #9"
{{DEFAULTSORT:Betts-LaCroix, Joe
1962 births
Living people
Harvard College alumni
Massachusetts Institute of Technology alumni
Businesspeople from the San Francisco Bay Area
American scientists