John Rodney Guest, FRS (born 27 December 1935) is a British molecular microbiologist. He was born the son of Sidney Ramsey Guest in Leeds, West Yorkshire and educated at the

University of Leeds , mottoeng = And knowledge will be increased , established = 1831 – Leeds School of Medicine1874 – Yorkshire College of Science1884 - Yorkshire College1887 – affiliated to the federal Victoria University1904 – University of Leeds , ...

(B.Sc. 1957) and

Trinity College, Oxford (That which you wish to be secret, tell to nobody) , named_for = The Holy Trinity , established = , sister_college = Churchill College, Cambridge , president = Dame Hilary Boulding , location = Broad Street, Oxford OX1 3BH , coordinates ...

(Ph.D. 1961). He worked as a Fellow at Oxford University from 1960 to 1965 and as a

Fulbright Scholar The Fulbright Program, including the Fulbright–Hays Program, is one of several United States Cultural Exchange Programs with the goal of improving intercultural relations, cultural diplomacy, and intercultural competence between the people of ...

Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is consider ...

in 1963–64. He was appointed Lecturer in Microbiology at the

University of Sheffield , mottoeng = To discover the causes of things , established = – University of SheffieldPredecessor institutions: – Sheffield Medical School – Firth College – Sheffield Technical School – University College of Sheffield , type = Pu ...

from 1965 to 1968, Senior Lecturer and Reader from 1968 to 1981 and has been Professor of Microbiology at Sheffield since 1981. He is known for his work on the application of mutant and genetic approaches to define the biochemistry and genetic make-up of central

anabolic Anabolism () is the set of metabolic pathways that construct molecules from smaller units. These reactions require energy, known also as an endergonic process. Anabolism is the building-up aspect of metabolism, whereas catabolism is the breaking-do ...

and

catabolic pathway Catabolism () is the set of metabolic pathways that breaks down molecules into smaller units that are either oxidized to release energy or used in other anabolic reactions. Catabolism breaks down large molecules (such as polysaccharides, lipid ...

s of bacteria, in particular the

citric acid cycle The citric acid cycle (CAC)—also known as the Krebs cycle or the TCA cycle (tricarboxylic acid cycle)—is a series of chemical reactions to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins ...

and related functions in both

aerobic Aerobic means "requiring air," in which "air" usually means oxygen. Aerobic may also refer to * Aerobic exercise, prolonged exercise of moderate intensity * Aerobics, a form of aerobic exercise * Aerobic respiration, the aerobic process of cellu ...

and

anaerobic metabolism Anaerobic respiration is respiration using electron acceptors other than molecular oxygen (O2). Although oxygen is not the final electron acceptor, the process still uses a respiratory electron transport chain. In aerobic organisms undergoing re ...

. In 1986 he was elected a

Fellow of the Royal Society Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, incl ...

and delivered their

Leeuwenhoek Lecture The Leeuwenhoek Lecture is a prize lecture of the Royal Society to recognize achievement in microbiology. The prize was originally given in 1950 and awarded annually, but from 2006 to 2018 was given triennially. From 2018 it will be awarded bienni ...

in 1995 on the subject of life without oxygen. He married Barbara Dearsley in 1962 and had a son (Chris Guest b.1968) and 2 daughters (Sue Guest b.1963 and Julia Guest b.1965).

References

{{DEFAULTSORT:Guest, John Rodney 1935 births Living people British microbiologists Alumni of the University of Leeds Alumni of Trinity College, Oxford Fellows of the Royal Society Academics of the University of Sheffield