John Puskas
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John D. Puskas is an American researcher, author, inventor and cardiovascular surgeon. As of 2022, he is Professor,
Cardiovascular The blood circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate. It includes the cardiovascular system, or vascular system, tha ...
Surgery,
Icahn School of Medicine The Icahn School of Medicine at Mount Sinai (ISMMS or Mount Sinai), formerly the Mount Sinai School of Medicine, is a private medical school in New York City. It is the academic teaching arm of the Mount Sinai Health System, which manages eight ...
at Mount Sinai, and Chairman, Department of Cardiovascular Surgery at
Mount Sinai Morningside Mount Sinai Morningside, formerly known as Mount Sinai St. Luke's, is a teaching hospital located in the Morningside Heights neighborhood of Manhattan in New York City. It is affiliated with the Icahn School of Medicine at Mount Sinai and the ...
,
Mount Sinai Beth Israel Mount Sinai Beth Israel is a 799-bed teaching hospital in Manhattan. It is part of the Mount Sinai Health System, a nonprofit health system formed in September 2013 by the merger of Continuum Health Partners and Mount Sinai Medical Center, and a ...
and
Mount Sinai West Mount Sinai West, opened in 1871 as Roosevelt Hospital, is affiliated with the Icahn School of Medicine at Mount Sinai and the Mount Sinai Health System. The 514-bed facility is located in the Midtown West neighborhood of New York City. The fac ...
. He holds 11 U.S. patents and co-founded the International Coronary Congress and the International Society for Coronary Artery Surgery. He is credited by
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with 330 publications and 15,234 citations and as of 2022
Scopus Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-l ...
reports an
h-index The ''h''-index is an author-level metric that measures both the productivity and citation impact of the publications, initially used for an individual scientist or scholar. The ''h''-index correlates with obvious success indicators such as winn ...
of 62. Puskas is known for advancing
coronary artery bypass Coronary artery bypass surgery, also known as coronary artery bypass graft (CABG, pronounced "cabbage") is a surgical procedure to treat coronary artery disease (CAD), the buildup of plaques in the arteries of the heart. It can relieve chest p ...
(
CABG Coronary artery bypass surgery, also known as coronary artery bypass graft (CABG, pronounced "cabbage") is a surgical procedure to treat coronary artery disease (CAD), the buildup of plaques in the arteries of the heart. It can relieve Angina pe ...
) surgery by refining surgical techniques for all-arterial, off-pump CABG and inventing finer instruments to be used for advanced coronary bypass surgical procedures. He is credited with performing the first totally thoracoscopic bilateral pulmonary vein isolation procedure. He is the co-editor of ''State of the Art Surgical Coronary
Revascularization In medical and surgical therapy, revascularization is the restoration of perfusion to a body part or organ that has had ischemia. It is typically accomplished by surgical means. Vascular bypass and angioplasty are the two primary means of reva ...
'', the first textbook solely devoted to coronary artery surgery. In 2021, Puskas ran the
New York City Marathon The New York City Marathon (currently branded TCS New York City Marathon after its headline sponsor) is an annual marathon () that courses through the five boroughs of New York City. It is the largest marathon in the world, with 53,627 finishe ...
with his patient who, in 2018, suffered cardiac arrest and was clinically dead for five minutes, but recovered after all-arterial CABG. Their trainer, John Garlepp was another CABG patient of Puskas.


Career


Life and education

Puskas received his MD at
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
in 1986 and in 1991, a Master of Science in Surgical Science (
MSc MSC may refer to: Computers * Message Sequence Chart * Microelectronics Support Centre of UK Rutherford Appleton Laboratory * MIDI Show Control * MSC Malaysia (formerly known as Multimedia Super Corridor) * USB mass storage device class (USB MSC ...
) at the
University of Toronto The University of Toronto (UToronto or U of T) is a public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution ...
. Post-graduate training included a general surgery internship and residency, department of surgery,
Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United Stat ...
; fellowship in
cardiothoracic surgery Cardiothoracic surgery is the field of medicine involved in surgical treatment of organs inside the thoracic cavity — generally treatment of conditions of the heart ( heart disease), lungs (lung disease), and other pleural or mediastinal st ...
at
Emory University Hospital Emory University Hospital is a 733-bed facility in Atlanta, Georgia, specializing in the care of acutely ill adults. Emory University Hospital is staffed exclusively by Emory University School of Medicine faculty who also are members of The Emor ...
s,
Atlanta Atlanta ( ) is the capital and most populous city of the U.S. state of Georgia. It is the seat of Fulton County, the most populous county in Georgia, but its territory falls in both Fulton and DeKalb counties. With a population of 498,715 ...
, a
lung transplantation Lung transplantation, or pulmonary transplantation, is a surgical procedure in which one or both lungs are replaced by lungs from a donor. Donor lungs can be retrieved from a living or deceased donor. A living donor can only donate one lung lobe. ...
research fellowship, division of
thoracic The thorax or chest is a part of the anatomy of humans, mammals, and other tetrapod animals located between the neck and the abdomen. In insects, crustaceans, and the extinct trilobites, the thorax is one of the three main divisions of the crea ...
surgery,
Toronto General Hospital The Toronto General Hospital (TGH) is a major teaching hospital in Toronto, Ontario, Canada and the flagship campus of University Health Network (UHN). It is located in the Discovery District of Downtown Toronto along University Avenue's Hospital ...
; and an advanced fellowship in
trachea The trachea, also known as the windpipe, is a Cartilage, cartilaginous tube that connects the larynx to the bronchi of the lungs, allowing the passage of air, and so is present in almost all air-breathing animals with lungs. The trachea extends ...
l surgery,
Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United Stat ...
, Division of General
Thoracic Surgery Cardiothoracic surgery is the field of medicine involved in surgical treatment of organs inside the thoracic cavity — generally treatment of conditions of the heart (heart disease), lungs (lung disease), and other pleural or mediastinal struc ...
.


Research

Puskas research concentrations include arterial bypass grafting, robotic and hybrid coronary bypass grafting, novel designs and materials for artificial heart valves, mitral and aortic valve repair and replacement, surgical and medical treatments for people with atrial fibrillation and surgical instruments for adult cardiac surgery. He founded the
Emory University Emory University is a private research university in Atlanta, Georgia. Founded in 1836 as "Emory College" by the Methodist Episcopal Church and named in honor of Methodist bishop John Emory, Emory is the second-oldest private institution of ...
Cardiothoracic Cardiothoracic surgery is the field of medicine involved in surgical treatment of organs inside the thoracic cavity — generally treatment of conditions of the heart (heart disease), lungs (lung disease), and other pleural or mediastinal struct ...
Clinical Research Unit in 2005 and was a founding investigator in the creation of the
NIH The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
Cardiothoracic Surgery Trials Network in 2007; he has served on the steering committee of that NIH Network since that time. As of 2022, he has served as the
principal investigator In many countries, the term principal investigator (PI) refers to the holder of an independent grant and the lead researcher for the grant project, usually in the sciences, such as a laboratory study or a clinical trial. The phrase is also often us ...
(PI) of five multi-center
FDA The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food s ...
investigatory drug/device exemption trials in cardiovascular surgery. At
Mount Sinai Health System The Mount Sinai Health System is a hospital network in New York City. It was formed in September 2013 by merging the operations of Continuum Health Partners and the Mount Sinai Medical Center. The Health System is structured around eight hospit ...
, he founded and directs the Cardiovascular Clinical Research Unit at Mount Sinai Morningside and Mount Sinai Beth Israel Hospitals to create a multidisciplinary collaborative clinical research infrastructure allowing clinical cardiologists and surgeons to enroll patients in multiple trials. He led 47 clinical sites nationwide to conduct the first RCT of hybrid coronary revascularization. He is listed on NIH RePORTER with 12 NHLBI PI roles.


Clinical and practice

Puskas performs cardiovascular surgical procedures including all-arterial coronary bypass grafting, minimally invasive robotic coronary bypass surgery, hybrid coronary
revascularization In medical and surgical therapy, revascularization is the restoration of perfusion to a body part or organ that has had ischemia. It is typically accomplished by surgical means. Vascular bypass and angioplasty are the two primary means of reva ...
, off-pump coronary artery bypass surgery,
ablation Ablation ( la, ablatio – removal) is removal or destruction of something from an object by vaporization, chipping, erosion, erosive processes or by other means. Examples of ablative materials are described below, and include spacecraft materi ...
surgery for the treatment of atrial fibrillation,
mitral valve The mitral valve (), also known as the bicuspid valve or left atrioventricular valve, is one of the four heart valves. It has two cusps or flaps and lies between the left atrium and the left ventricle of the heart. The heart valves are all one-w ...
repair/replacement,
aortic valve The aortic valve is a valve in the heart of humans and most other animals, located between the left ventricle and the aorta. It is one of the four valves of the heart and one of the two semilunar valves, the other being the pulmonary valve. The ...
replacement, valve-sparing aortic root replacement and surgery for
aortic dissection Aortic dissection (AD) occurs when an injury to the innermost layer of the aorta allows blood to flow between the layers of the aortic wall, forcing the layers apart. In most cases, this is associated with a sudden onset of severe chest or ...
. He performed the first triple off-pump bypass surgery using minimally invasive coronary artery bypass graft instrumentation in 1997. Between 1996 and 2022, he performed approximately 300 cardiac surgical cases annually, specializing in multiple arterial
CABG Coronary artery bypass surgery, also known as coronary artery bypass graft (CABG, pronounced "cabbage") is a surgical procedure to treat coronary artery disease (CAD), the buildup of plaques in the arteries of the heart. It can relieve Angina pe ...
and robotic CABG. In 2019, Puskas, with Gianluca Torregrossa, MD, successfully performed two totally endoscopic coronary arterial bypass surgeries ( TECABs) making Mount Sinai the only New York State health system qualified to make the procedure available. As of 2022, Puskas has served as President of the International Society for Minimally Invasive Cardiothoracic Surgery (2009) and the International Society for Coronary Artery Surgery.


U.S. patents


Present societies

* International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS) *
Society of Thoracic Surgeons The Society of Thoracic Surgeons is a Chicago, Illinois (US)-based medical specialty professional society in the field of cardiothoracic surgery Cardiothoracic surgery is the field of medicine involved in surgical treatment of organs inside the ...
*
American College of Surgeons The American College of Surgeons is an educational association of surgeons created in 1913.American College of Surgeons Online "What is the American College of Surgeons?"/ref> See also *American College of Physicians The American College o ...
*
American Association for Thoracic Surgery The American Association for Thoracic Surgery (AATS) is an international association of cardiothoracic surgeons. It was founded in 1917 by the earliest pioneers in the field of thoracic surgery. Headquartered in Beverly, Massachusetts, it has over ...
*
American College of Chest Physicians The American College of Chest Physicians (CHEST) is a medical association in the United States consisting of physicians and non-physician specialists in the field of chest medicine, which includes pulmonology, critical care medicine, and sleep med ...
*
American College of Cardiology The American College of Cardiology (ACC), based in Washington, D.C., is a nonprofit medical association established in 1949. It bestows credentials upon cardiovascular specialists who meet its qualifications. Education is a core component of the ...
''*Present indicates 2022''


Publications


Editorial

As of 2022, Puskas is a reviewer and editorial contributor to nine journals, including Annuals Thoracic Surgery,
Journal of Thoracic and Cardiovascular Surgery ''The Journal of Thoracic and Cardiovascular Surgery'' is a monthly peer-reviewed medical journal covering cardiothoracic surgery, cardiology, pulmonary medicine, and vascular disease published by Elsevier. It is the official journal of the Ame ...
, Heart Surgery Forum, The Lancet, The
Journal of Cardiac Surgery The ''Journal of Cardiac Surgery'' is a peer-reviewed medical journal about cardiology and surgery that was established in March 1986. The current editor in chief of the journal is Tomas Salerno of the University of Miami The University of ...
, Circulation,
Innovations Innovation is the practical implementation of ideas that result in the introduction of new goods or services or improvement in offering goods or services. ISO TC 279 in the standard ISO 56000:2020 defines innovation as "a new or changed entit ...
,
American College of Cardiology The American College of Cardiology (ACC), based in Washington, D.C., is a nonprofit medical association established in 1949. It bestows credentials upon cardiovascular specialists who meet its qualifications. Education is a core component of the ...
, European Association for Cardiothoracic Surgery.


Peer reviewed

PubMed lists 320 publications as of 2022. A short list ranked by citations include: Smith, P. K., Puskas, J. D., Ascheim, D. D., Voisine, P., Gelijns, A. C., Moskowitz, A. J., ... & Michler, R. E. (2014). Surgical treatment of moderate ischemic mitral regurgitation. ''New England Journal of Medicine'', ''371''(23), 2178-2188; 273 citations Puskas, J. D., Thourani, V. H., Marshall, J. J., Dempsey, S. J., Steiner, M. A., Sammons, B. H., ... & Guyton, R. A. (2001). Clinical outcomes, angiographic patency, and resource utilization in 200 consecutive off-pump coronary bypass patients. ''The Annals of thoracic surgery'', ''71''(5), 1477-1484; 324 citations Gaudino, M., Benedetto, U., Fremes, S., Biondi-Zoccai, G., Sedrakyan, A., Puskas, J. D., ... & Taggart, D. P. (2018). Radial-artery or saphenous-vein grafts in coronary-artery bypass surgery. ''New England Journal of Medicine'', ''378''(22), 2069-2077; 295 citations Gillinov, A. M., Gelijns, A. C., Parides, M. K., DeRose Jr, J. J., Moskowitz, A. J., Voisine, P., ... & Argenziano, M. (2015). Surgical ablation of atrial fibrillation during mitral-valve surgery. ''New England Journal of Medicine'', ''372''(15), 1399-1409; 261 citations El-Chami, M. F., Kilgo, P., Thourani, V., Lattouf, O. M., Delurgio, D. B., Guyton, R. A., ... & Puskas, J. D. (2010). New-onset atrial fibrillation predicts long-term mortality after coronary artery bypass graft. ''Journal of the American College of Cardiology'', ''55''(13), 1370-1376; 338 citations


Books and chapters

''State of the Art Surgical Coronary Revascularization''. Winston AD and Puskas JD. "''Techniques for Multivessel OPCAB''". Minimally Invasive Cardiac Surgery. 2ndEdition, edited by Oz MC and Goldstein DJ, Humana Press, 2003. Sharoni E and Puskas JD. "''Techniques in Multivessel OPCAB''". Operative Cardiac Surgery, edited by Gardner T J and Spray TL, Arnold Publishers, 2004. Thourani VH and Puskas JD. "''Coronary Artery Bypass Procedures·Medical Management of the Surgical Patient''." Fourth Edition, edited by Lubin MF, Walker HK, Smith RB III, 2006. Song HK and Puskas JD. "''Off-pump Coronary Artery Bypass Surgery''". Mastery of Cardiothoracic Surgery, 2nd Edition, Lippincott Williams and Wilkins, New York, 2007. Richard J. Myung and John D. Puskas. "''Off-Pump Coronary Artery Bypass Grafting for Repeat Coronary Revascularization''", Redo Cardiac Surgery in Adults, 2nd Edition, Edited by Venkat R. Machiraju, Hartzell V. Schaff and Lars G. Svensson. Springer. 2011. Michael E. Halkos, John D. Puskas. "''Minimally Invasive Coronary Artery Bypass Graft to Cardiac Surgery: Recent Advances and Techniques''", 2012. Yanagawa B and Puskas JD. “''Off-Pump Coronary Artery Bypass Grafting''”, in Mastery of Techniques in Cardiac Surgery, 2016. Michael E. Halkos, Emmanuel Moss, and John D. Puskas. “''Chapter 2 Off-pump versus on-pump coronary artery bypass grafting''”, in Core Concepts in Cardiac Surgery, Edited by David Taggart and Yasir Abu-Omar, Oxford University Press, 2018. Bobby Yanagawa, Michael E. Halkos, John D. Puskas. “''Chapter 21: Myocardial Revascularization Without Cardiopulmonary Bypass''”, in Cardiac Surgery in the Adult, 5e, Edited by Lawrence H. Cohn, David H. Adams, Cenveo® Publisher Services, 2018.


See also

* Mario Gaudino - cardiac surgeon and expert in coronary revascularization


References


External links


The Cardiothoracic Surgery Network

The Society of Thoracic Surgeons

American Association for Thoracic Surgery

International Society for Minimally Invasive Cardiothoracic Surgery

International Coronary Congress
{{DEFAULTSORT:Puskas, John American cardiac surgeons American thoracic surgeons American cardiologists Icahn School of Medicine at Mount Sinai faculty Harvard Medical School alumni Massachusetts General Hospital residents 20th-century surgeons 21st-century surgeons Cardiovascular researchers Living people Year of birth missing (living people)