John Wayne Kappler (born December 22, 1943, in
Baltimore, Maryland
Baltimore ( , locally: or ) is the List of municipalities in Maryland, most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic (United States), Mid-Atlantic, and List of United States cities by popula ...
) is a professor in the Department of Integrated Immunology at
National Jewish Health
National Jewish Health is a Denver, Colorado academic hospital/clinic doing research and treatment in respiratory, cardiac, immune and related disorders. It is an internationally respected medical center that draws people from many countries to ...
. His principal research is in
T cell biology, a subject he collaborates on with his wife
Philippa Marrack
Philippa "Pippa" Marrack, FRS (born 28 June 1945) is an English immunologist and academic, based in the United States, best known for her research and discoveries pertaining to T cells. Marrack is the Ida and Cecil Green Professor and chair of ...
.
[ Rennie, J. (1992) ''Profile: Philippa Marrack and John Kappler – Keeping It In the Family'', ]Scientific American
''Scientific American'', informally abbreviated ''SciAm'' or sometimes ''SA'', is an American popular science magazine. Many famous scientists, including Albert Einstein and Nikola Tesla, have contributed articles to it. In print since 1845, it i ...
267(2), 43-44. In 1983 they discovered the
T cell receptor
The T-cell receptor (TCR) is a protein complex found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules. The binding b ...
, together with Ellis Reinherz and
James Allison.
Awards
*1986 – Appointed investigator,
Howard Hughes Medical Institute
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fil ...
*1989 – Elected member,
National Academy of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
*1993 – Cancer Research Institute
William B. Coley Award
The William B. Coley Award for Distinguished Research in Basic and Tumor Immunology is presented annually by the Cancer Research Institute, to scientists who have made outstanding achievements in the fields of basic and tumor immunology and whose w ...
*1993 -
Paul Ehrlich and Ludwig Darmstaedter Prize
The Paul Ehrlich and Ludwig Darmstaedter Prize is an annual award bestowed by the since 1952 for investigations in medicine. It carries a prize money of 120,000 Euro. The prize awarding ceremony is traditionally held on March 14, the birthday of N ...
*1994 –
Louisa Gross Horwitz Prize
The Louisa Gross Horwitz Prize for Biology or Biochemistry is an annual prize awarded by Columbia University to a researcher or group of researchers who have made an outstanding contribution in basic research in the fields of biology or biochemist ...
for Biology or Biochemistry (
Columbia University
Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
)
*2015 –
Wolf Prize in Medicine
The Wolf Prize in Medicine is awarded annually by the Wolf Foundation in Israel. It is one of the six Wolf Prizes established by the Foundation and awarded since 1978; the others are in Agriculture, Chemistry, Mathematics, Physics and Arts. The P ...
References
1943 births
Living people
American immunologists
Members of the United States National Academy of Sciences
Howard Hughes Medical Investigators
University of Denver faculty
Members of the National Academy of Medicine
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