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John Hughes Bennett PRCPE
FRSE Fellowship of the Royal Society of Edinburgh (FRSE) is an award granted to individuals that the Royal Society of Edinburgh, Scotland's national academy of science and letters, judged to be "eminently distinguished in their subject". This soci ...
(31 August 1812 – 25 September 1875) was an English physician,
physiologist Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical a ...
and
pathologist Pathology is the study of the causal, causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when us ...
. His main contribution to medicine has been the first description of
leukemia Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ' ...
as a
blood disorder Hematologic diseases are disorders which primarily affect the blood & blood-forming organs. Hematologic diseases include rare genetic disorders, anemia, HIV, sickle cell disease & complications from chemotherapy or transfusions. Myeloid * Hemog ...
(1845). The first person to describe leukemia as an unknown disease was
Alfred François Donné Alfred François Donné (13 September 1801 – 7 March 1878) was a French bacteriologist and doctor. He was born in Noyon, France, and died in Paris. Donné was the discoverer of Trichomonas vaginalis. He was also the inventor of the photomicrogr ...
. Bennett was the first doctor to describe
aspergillosis Aspergillosis is a fungal infection of usually the lungs, caused by the genus ''Aspergillus'', a common mould that is breathed in frequently from the air around, but does not usually affect most people. It generally occurs in people with lung dise ...
. In his seminal paper published in 1842 entitled "On the parasitic vegetable structures found growing in living animals" he makes the very first description of ''
Aspergillus ' () is a genus consisting of several hundred mold species found in various climates worldwide. ''Aspergillus'' was first catalogued in 1729 by the Italian priest and biologist Pier Antonio Micheli. Viewing the fungi under a microscope, Miche ...
'' (a pathogenic fungus) growing in the lung tissue of humans.


Biography

Born in London, he was educated at Mount Radford School in
Exeter Exeter () is a city in Devon, South West England. It is situated on the River Exe, approximately northeast of Plymouth and southwest of Bristol. In Roman Britain, Exeter was established as the base of Legio II Augusta under the personal comm ...
, and being destined for the medical profession he entered an apprenticeship with Mr Sedgwick, a surgeon in
Maidstone Maidstone is the largest Town status in the United Kingdom, town in Kent, England, of which it is the county town. Maidstone is historically important and lies 32 miles (51 km) east-south-east of London. The River Medway runs through the c ...
. In 1833 he began his studies at
Edinburgh Edinburgh ( ; gd, Dùn Èideann ) is the capital city of Scotland and one of its 32 Council areas of Scotland, council areas. Historically part of the county of Midlothian (interchangeably Edinburghshire before 1921), it is located in Lothian ...
, and in 1837 graduated with the highest honours and a gold medal, with a dissertation entitled ''The Physiology and Pathology of the Brain''. During his last year at Edinburgh he was elected President of the
Royal Medical Society The Royal Medical Society (RMS) is a society run by students at the University of Edinburgh Medical School, Scotland. It claims to be the oldest medical society in the United Kingdom although this claim is also made by the earlier London-based ...
,
Royal Physical Society of Edinburgh The Royal Physical Society of Edinburgh was a learned society based in Edinburgh, Scotland "for the cultivation of the physical sciences". The society was founded in 1771 as the Physico-Chirurgical Society but soon after changed its name to the ...
, and a vice-president of the Anatomical and Physiological Society. During the next two years he studied in Paris (where he founded the English-speaking Medical Society) and then spent two in Germany (mainly at Heidelberg and the
Charité The Charité – Universitätsmedizin Berlin (Charité – Berlin University of Medicine) is one of Europe's largest university hospitals, affiliated with Humboldt University and Free University Berlin. With numerous Collaborative Research Cen ...
Hospital in Berlin), before returning to Edinburgh in 1841 where he published a ''Treatise on Cod-liver Oil as a Therapeutic Agent''. In the same year he began to lecture as an extra-academical teacher on
histology Histology, also known as microscopic anatomy or microanatomy, is the branch of biology which studies the microscopic anatomy of biological tissues. Histology is the microscopic counterpart to gross anatomy, which looks at larger structures vis ...
, drawing attention to the importance of the
microscope A microscope () is a laboratory instrument used to examine objects that are too small to be seen by the naked eye. Microscopy is the science of investigating small objects and structures using a microscope. Microscopic means being invisibl ...
in the investigation of disease; and as physician to the
Royal Public Dispensary of Edinburgh The Public Dispensary of Edinburgh was the first free-of-charge hospital in Scotland. History Edinburgh has a history of providing free medical care to the poor. In first meeting of the Royal College of Physicians of Edinburgh, in 1681, the F ...
he instituted courses of polyclinical medicine. In 1843 he was elected a Fellow of the
Royal Society of Edinburgh The Royal Society of Edinburgh is Scotland's national academy of science and letters. It is a registered charity that operates on a wholly independent and non-partisan basis and provides public benefit throughout Scotland. It was established i ...
his proposer being Sir
Robert Christison Sir Robert Christison, 1st Baronet, (18 July 1797 – 27 January 1882) was a Scottish toxicologist and physician who served as president of the Royal College of Physicians of Edinburgh (1838–40 and 1846-8) and as president of the British ...
. His address was then listed as 1 Glenfinlas Street, just off
Charlotte Square 300px, Robert Adam's palace-fronted north side Charlotte Square is a garden square in Edinburgh, Scotland, part of the New Town, designated a UNESCO World Heritage Site. The square is located at the west end of George Street and was intended ...
. In the same year he was appointed professor of the Institutes of Medicine at Edinburgh, and performed the duties of that chair with great energy until incapacitated by failing health, in 1874. In 1845, Bennett published a paper entitled a ''Case of Hypertrophy of the Spleen and Liver in which Death Took Place from Suppuration of the Blood'', the first recorded case of
leukemia Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ' ...
, then known as
leucocythemia Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. Symptoms may include ...
, in the ''Edinburgh Medical and Surgical Journal''. In 1849, Bennett was elected as a member to the
American Philosophical Society The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and communit ...
. In 1855 he was a prime opponent of
Thomas Laycock Thomas Laycock (1786 – 7 November 1823) was an English soldier, explorer, and later businessman, who served in North America during the War of 1812, but is most famous for being the first European to travel overland through the interior of Ta ...
for the Edinburgh Chair. His obituary refers to this as an "exciting contest". Michalel Barfoot wrote in 1995 that in fact extremely bitter, and became a source of great dissension in subsequent years. Barfoot describes him as having "the personality biographers' dreams are made of", and quotes Bennett's biographer
John M'Kendrick John is a common English name and surname: * John (given name) * John (surname) John may also refer to: New Testament Works * Gospel of John, a title often shortened to John * First Epistle of John, often shortened to 1 John * Second E ...
as stating that Bennett "regarded his defeat (by Laycock) as the great disappointment of his life, and there is little doubt that it tended to a certain extent to distort his views of men an things". In 1859 he was elected President of the
Harveian Society The Harveian Society of London, named after the physician William Harvey, is a medical society and registered charity, founded in 1831. Doctors assemble regularly at the Medical Society of London, Chandos Street, Cavendish Square to converse and d ...
. In 1873, he was elected a member of the
French Academy of Medicine French (french: français(e), link=no) may refer to: * Something of, from, or related to France ** French language, which originated in France, and its various dialects and accents ** French people, a nation and ethnic group identified with France ...
and granted recognition by the French government to practice medicine in France. In August 1875 he was able to be present at the meeting of the
British Medical Association The British Medical Association (BMA) is a registered trade union for doctors in the United Kingdom. The association does not regulate or certify doctors, a responsibility which lies with the General Medical Council. The association's headquar ...
in Edinburgh, on which occasion he received the degree of LL.D., but the fatigue he then underwent brought on a relapse, and he was compelled to have the operation of
lithotomy Lithotomy from Greek for "lithos" (stone) and "tomos" (cut), is a surgical method for removal of calculi, stones formed inside certain organs, such as the urinary tract (kidney stones), bladder (bladder stones), and gallbladder (gallstones), tha ...
performed. He sank rapidly and died on 25 September 1875 at
Norwich Norwich () is a cathedral city and district of Norfolk, England, of which it is the county town. Norwich is by the River Wensum, about north-east of London, north of Ipswich and east of Peterborough. As the seat of the See of Norwich, with ...
. Bennett died at
Norwich Norwich () is a cathedral city and district of Norfolk, England, of which it is the county town. Norwich is by the River Wensum, about north-east of London, north of Ipswich and east of Peterborough. As the seat of the See of Norwich, with ...
on 25 September 1875, nine days after an operation for stone, performed by Mr. Cadge, from which his enfeebled strength did not enable him to recover. He was buried in the
Dean Cemetery The Dean Cemetery is a historically important Victorian cemetery north of the Dean Village, west of Edinburgh city centre, in Scotland. It lies between Queensferry Road and the Water of Leith, bounded on its east side by Dean Path and on ...
, Edinburgh, on 30 September by the side of his friends Goodsir and Edward Forbes.


Works

His publications were very numerous including ''Lectures on Clinical Medicine'' (1850–1856), which in second and subsequent editions were calle
''Clinical Lectures on the Principles and Practice of Medicine''
and were translated into various languages, including Russian and
Hindi Hindi (Devanāgarī: or , ), or more precisely Modern Standard Hindi (Devanagari: ), is an Indo-Aryan language spoken chiefly in the Hindi Belt region encompassing parts of northern, central, eastern, and western India. Hindi has been de ...
; ''Leucocythaemia'' (1852), the first recorded cure of which was published by him in 1845; ''Outlines of Physiology'' (1858), reprinted from the 8th edition of the ''
Encyclopædia Britannica The (Latin for "British Encyclopædia") is a general knowledge English-language encyclopaedia. It is published by Encyclopædia Britannica, Inc.; the company has existed since the 18th century, although it has changed ownership various time ...
'', ''Pathology and Treatment of Pulmonary
Tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
'' (1853); ''Textbook of Physiology'' (1871–1872). Because Bennett introduced practical classes in the teaching of physiology, he is considered the father of physiological education in
medical school A medical school is a tertiary educational institution, or part of such an institution, that teaches medicine, and awards a professional degree for physicians. Such medical degrees include the Bachelor of Medicine, Bachelor of Surgery (MBBS, M ...
s. He was also the first to teach the clinical use of the microscope systematically and its uses in the teaching of pathology and physiology. He opposed
bloodletting Bloodletting (or blood-letting) is the withdrawal of blood from a patient to prevent or cure illness and disease. Bloodletting, whether by a physician or by leeches, was based on an ancient system of medicine in which blood and other bodily flu ...
and was highly influential in changing medical therapeutics towards a more science-based approach in the second half of the 19th century. He supported the admission of women to medical schools and advocated a better interaction between medical specialities.


Memorials

In 1901, the
University of Edinburgh The University of Edinburgh ( sco, University o Edinburgh, gd, Oilthigh Dhùn Èideann; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Granted a royal charter by King James VI in 15 ...
inaugurated the ''John Hughes Bennett Laboratory of Experimental Pathology'', in homage to "one of that galaxy of talent and genius that illuminated Edinburgh in the middle decades of the last century". A second laboratory with his name was opened in 1998, in a joint venture between Britain's Leukaemia Research Fund, the University of Edinburgh and the
Western General Hospital The Western General Hospital (often abbreviated to simply ‘The Western General’) is a health facility at Craigleith, Edinburgh, Scotland. It is managed by NHS Lothian. History The hospital was designed by Peddie and Kinnear and opened as ...
Trust.


Family

On 22 August 1844 Bennett married Jessie Samuel (1824–1906), a niece of the Reverend Alexander Simpson (later moderator of the Church of Scotland). They had a son Dr Alexander Hughes Bennett (1848-1901) who became a consultant neurologist in
London London is the capital and largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary down to the North Sea, and has been a majo ...
and four daughters. Their daughter Harriet Sophia Bennett (1850-1905), married Robert Cox MP.


Freemasonry

Rhind was a Scottish Freemason. He was Initiated in Lodge Canongate Kilwinning, No. 2, on 23 November 1836.History of the Lodge Canongate Kilwinning, No.2, compiled from the records 1677-1888
By Alan MacKenzie. 1888. P.238.


Notes


References

* * * * Attribution * *


Further reading

* * * *


External links


Lodge Canongate Kilwinning, No. 2 (Edinburgh)
{{DEFAULTSORT:Bennett, John Hughes 1812 births 1875 deaths Alumni of the University of Edinburgh British pathologists Scottish Freemasons 19th-century English medical doctors