John C. Crabbe, Jr. is an American neuroscientist and behavior geneticist. He is a professor of behavioral neuroscience at the

Oregon Health & Science University Oregon Health & Science University (OHSU) is a public research university focusing primarily on health sciences with a main campus, including two hospitals, in Portland, Oregon. The institution was founded in 1887 as the University of Oregon Medi ...

(OHSU) School of Medicine, where he has worked since 1979. He is also a senior research career scientist at the Veterans Affairs Medical Center in

Portland Portland most commonly refers to: * Portland, Oregon, the largest city in the state of Oregon, in the Pacific Northwest region of the United States * Portland, Maine, the largest city in the state of Maine, in the New England region of the northeas ...

Oregon Oregon () is a U.S. state, state in the Pacific Northwest region of the Western United States. The Columbia River delineates much of Oregon's northern boundary with Washington (state), Washington, while the Snake River delineates much of it ...

. He is also the former director of OHSU's Portland Alcohol Research Center. Crabbe is known for his research using

mouse model A model organism (often shortened to model) is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the model organism will provide insight into the working ...

s to study the

pharmacogenetics Pharmacogenomics is the study of the role of the genome in drug response. Its name ('' pharmaco-'' + ''genomics'') reflects its combining of pharmacology and genomics. Pharmacogenomics analyzes how the genetic makeup of an individual affects the ...

alcoholism Alcoholism is, broadly, any drinking of alcohol (drug), alcohol that results in significant Mental health, mental or physical health problems. Because there is disagreement on the definition of the word ''alcoholism'', it is not a recognize ...

. He is also known for a 1999 study he and his colleagues published documenting significant variations in certain mouse behaviors across different labs, even when they all tried to follow the same protocols. In 2011, he was chosen by the

National Institute on Alcohol Abuse and Alcoholism The National Institute on Alcohol Abuse and Alcoholism (NIAAA), as part of the U.S. National Institutes of Health, supports and conducts biomedical and behavioural research on the causes, consequences, treatment, and prevention of alcoholism and ...

to give the 16th annual Mark Keller Honorary Lecture. Crabbe is a member of the

editorial board The editorial board is a group of experts, usually at a publication, who dictate the tone and direction the publication's editorial policy will take. Mass media At a newspaper, the editorial board usually consists of the editorial page editor, a ...

of ''

Genes, Brain and Behavior ''Genes, Brain and Behavior'' (also known as ''G2B'') is a peer-reviewed online-only scientific journal covering research in the fields of behavioural genetics, behavioral, neurogenetics, neural, and psychiatric genetics. It is published by Wiley- ...

''.

References

Living people American neuroscientists Behavior geneticists Oregon Health & Science University faculty Stanford University alumni University of Colorado Boulder alumni Researchers in alcohol abuse Year of birth missing (living people) Scientists from Portland, Oregon {{Neuroscientist-stub