Johannes Kornhuber (born September 11, 1959) is a German psychiatrist and psychotherapist.

Life

Kornhuber worked in the Department of Psychiatry at the

University of Würzburg The Julius Maximilian University of Würzburg (also referred to as the University of Würzburg, in German ''Julius-Maximilians-Universität Würzburg'') is a public research university in Würzburg, Germany. The University of Würzburg is one of ...

, Germany, as Postdoctoral Fellow, Resident and Supervising Physician. In 1996 he obtained an appointment to a full professorship in the Department of Psychiatry at the

University of Göttingen The University of Göttingen, officially the Georg August University of Göttingen, (german: Georg-August-Universität Göttingen, known informally as Georgia Augusta) is a public research university in the city of Göttingen, Germany. Founded ...

, Germany, where he was Chairman of the Gerontopsychiatric Section. Since 2000, Kornhuber has been a full professor and chairman in the Department of Psychiatry at the

University of Erlangen-Nuremberg A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, ...

, Germany.

Work

His research interests include the pathophysiology of Alzheimer’s disease, the early diagnosis and treatment of dementia syndromes, the pathophysiology of alcohol addiction and the pathophysiology of major depressive disorder. He has authored or co-authored more than 400 Journal articles. Kornhuber described novel molecular mechanisms of approved psychotropic drugs, namely that memantine, amantadine, budipine and orphenadrine act as low-affinity NMDA-receptor antagonists. The data obtained with memantine formed an important basis for its worldwide approval as an antidementive drug. Kornhuber developed the pharmacokinetic hypothesis explaining the delayed therapeutic effects of antidepressant drugs. Furthermore, he found that antidepressant drugs like amitriptyline and fluoxetine mediate their effects on neurogenesis and behavior by lowering ceramide abundance in the brain.Kornhuber J, Müller CP, et al. ''The ceramide system as a novel antidepressant target''. In: ''

Trends in Pharmacological Sciences A fad or trend is any form of collective behavior that develops within a culture, a generation or social group in which a group of people enthusiastically follow an impulse for a short period. Fads are objects or behaviors that achieve short- ...

''. 35:293-304,2014, Among his coauthors has been Peter Riederer.

Honors

* Scientific Award of the German Society for Psychiatry (1990) * Organon-Award of the German Society for Biological Psychiatry (1990) * Rafaelsen Award of the Collegium Internationale Neuro-Psychopharmacologicum (1994) * Scientific Award of the Senator Dr. Franz Burda-Foundation (1995) * Klaesi-Award, Swiss Academy of Medical Sciences (1995) * Scientific Award for Psychopharmacology of the AGNP (1999) * Ehrenpreis – Deutscher Förderpreis für Schmerzforschung und Schmerztherapie (2000) * Award „ZukunftErfindenNRW“ Der HochschulWettbewerb 2011 3. Preis (together with Wiltfang J, Maler M, et al.) (2011) * Annika Liese-Award (together with Gulbins E) (2014) * Awards for Good Teaching, University of Erlangen-Nuremberg (2006, 2010, 2013, 2014, 2015)

References

External links

Publications in PubMedPublications in Google scholar
{{DEFAULTSORT:Kornhuber, Johannes German psychiatrists German psychotherapists Living people 1959 births Physicians from Freiburg im Breisgau University of Würzburg faculty University of Göttingen faculty University of Erlangen-Nuremberg faculty