Johannes Fabry (1 June 1860, in Jülich – 29 June 1930, in

Dortmund Dortmund (; Westphalian nds, Düörpm ; la, Tremonia) is the third-largest city in North Rhine-Westphalia after Cologne and Düsseldorf, and the eighth-largest city of Germany, with a population of 588,250 inhabitants as of 2021. It is the la ...

) was a German

dermatologist Dermatology is the branch of medicine dealing with the skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A dermatologist is a specialist medical ...

. He studied medicine at the universities of

Bern german: Berner(in)french: Bernois(e) it, bernese , neighboring_municipalities = Bremgarten bei Bern, Frauenkappelen, Ittigen, Kirchlindach, Köniz, Mühleberg, Muri bei Bern, Neuenegg, Ostermundigen, Wohlen bei Bern, Zollikofen , website ...

and

Berlin Berlin ( , ) is the capital and largest city of Germany by both area and population. Its 3.7 million inhabitants make it the European Union's most populous city, according to population within city limits. One of Germany's sixteen constitue ...

, receiving his doctorate in 1886. Following graduation he trained in dermatology under

Joseph Doutrelepont Louis Guillaume Joseph Doutrelepont (3 June 1834, Malmedy – 30 April 1918, Bonn) was a German surgeon and dermatologist. In 1858 he received his medical doctorate in Berlin, then furthered his education at the University of Bonn as a student ...

at the

University of Bonn The Rhenish Friedrich Wilhelm University of Bonn (german: Rheinische Friedrich-Wilhelms-Universität Bonn) is a public research university located in Bonn, North Rhine-Westphalia, Germany. It was founded in its present form as the ( en, Rhine U ...

and with Hugo Ribbert in

Zürich Zürich () is the list of cities in Switzerland, largest city in Switzerland and the capital of the canton of Zürich. It is located in north-central Switzerland, at the northwestern tip of Lake Zürich. As of January 2020, the municipality has 43 ...

. From 1889 to 1929 he was chief medical officer of the Skin Clinic at the

municipal hospital, which under his guidance, became a leading center for dermatology. His name is associated with "

Fabry disease Fabry disease, also known as Anderson–Fabry disease, is a rare genetic disease that can affect many parts of the body, including the kidneys, heart, and skin. Fabry disease is one of a group of conditions known as lysosomal storage diseases. T ...

", a rare, inherited metabolic disease characterized by telangiectatic skin lesions,

kidney failure Kidney failure, also known as end-stage kidney disease, is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. Kidney failure is classified as eit ...

and disorders of the

cardiovascular The blood circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate. It includes the cardiovascular system, or vascular system, tha ...

gastrointestinal The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans and ...

, and

central nervous system The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all par ...

s. In 1898 he described dermatological features of the disease in a 13-year-old boy, naming the condition "purpura haemorrhagica nodularis". The disease is also called "Anderson-Fabry disease", named along with British surgeon

William Anderson William Anderson may refer to: Arts and entertainment * William Anderson (artist) (1757–1837), painter of marine and historical paintings * William Anderson (theatre) (1868–1940), Australian stage entrepreneur * William Anderson (1911–1986), ...

, who independent of Fabry, reviewed the progression of the disease over nearly 20 years in a 39-year-old patient.Anderson-Fabry disease
Who Named It

Works by Fabry associated with Fabry disease

* ''Ein Beitrag zur Kenntnis der Purpura haemorrhagica nodularis (Purpura papulosa haemorrhagica Hebrae)''. Archiv für Dermatologie und Syphilis, Berlin, 1898, 43: 187-200. * ''Ueber einen Fall von Angiokeratoma circumscriptum am linken Oberschenkel''. Dermatologische Zeitschrift, 1915, 22: 1-4. * ''Zur Klinik und Ätiologie der Angiokeratoma''. Archiv für Dermatologie und Syphilis, Berlin, 1916, 123: 294-307. * ''Weiterer Beitrag zur Klinik des Angiokeratoma naeviforme (Naevus angiokeratosus)''. Dermatologische Wochenschrift, Hamburg, 1923, 90: 339.

References

{{DEFAULTSORT:Fabry, Johannes 1860 births 1930 deaths People from Jülich Humboldt University of Berlin alumni University of Bern alumni German dermatologists