Jill Escher
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Jill Escher is a former attorney and real estate developer. She is the head of the Escher Fund for Autism, the immediate past president of the
Autism Society of America The Autism Society of America (ASA) was founded in 1965 by Bernard Rimland and Ivar Lovaas together with Ruth C. Sullivan and a small group of other parents of children with autism. Its original name was the National Society for Autistic Childre ...
San Francisco Bay Area chapter, and the president of the National Council on Severe Autism. Escher is a graduate of
Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is consider ...
and the
UC Berkeley School of Law The University of California, Berkeley, School of Law (commonly known as Berkeley Law or UC Berkeley School of Law) is the law school of the University of California, Berkeley, a public research university in Berkeley, California. It is one of 1 ...
.


Research

Escher hypothesizes that the increasing prevalence and strong heritability of autism can in part be explained by non-genetic, environmentally informed events. In particular, her work stresses that heritable components of parental germ cells (egg and sperm and especially their precursors) can be damaged by exogenous toxicants such as tobacco smoke, general anesthesia, and synthetic steroid drugs, dysregulating brain-related gene expression in the offspring. The changes can manifest as changes in chromatin, epigenome, or
de novo mutations In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitos ...
. The Escher Fund for Autism awards grants each year to scientists undertaking pilot projects related to germ cell exposure to toxicants. Some scientists claim that she should also look into other causes of autism. Escher's hypothesis is based on her own personal story. When her mother was pregnant with her in 1965, she was administered very high, regular doses of synthetic steroid hormone drugs that were thought at the time to prevent miscarriage. After discovering this history at age 45, Escher hypothesized that these drugs disrupted the development of her fetal eggs, which ultimately caused two of her children to have autism. She is known for collaborating with scientific experts, speaking at scientific conferences, and for being elected as the only non-scientist to serve on the governing council of the Environmental Mutagenesis and Genomics Society. Escher has also petitioned the FDA to withdraw approval for two drugs until they can be tested for impacts on developing fetal germ cells, an anti-nausea drug approved for pregnant women, and the synthetic progestin marketed as Makena. Her papers published in scientific journals stress that more research needs to be done on germ line vulnerabilities to pharmaceuticals and chemicals. In 2013, Escher presented at the
Interagency Autism Coordinating Committee The Interagency Autism Coordinating Committee (IACC) is a United States federal advisory panel within the Department of Health and Human Services (HHS). It coordinates all efforts within HHS concerning autism spectrum disorder (ASD). The IACC was ...
about the germ cell exposure hypothesis of autism. In 2019, she was invited to present at the
National Institute of Environmental Health Sciences The National Institute of Environmental Health Sciences (NIEHS) conducts research into the effects of the environment on human disease, as one of the 27 institutes and centers of the National Institutes of Health (NIH). It is located in the Rese ...
about the importance of research on germline exposures. In 2021, Escher, along with
Wei Yan Wei Yan () (died October 234), courtesy name Wenchang, was a Chinese military general and politician of the state of Shu Han during the Three Kingdoms period of China. Originally a subordinate of the warlord Liu Bei in the late Eastern Han dy ...
,
Victor Corces Victor Corces (born August 16, 1952, in Asturias, Spain) is a professor of human genetics at Emory University. His work has focused on understanding the mechanisms by which chromosomes are folded in the three-dimensional nuclear space. He was el ...
, and others published an article in the
Journal of Autism and Developmental Disorders The ''Journal of Autism and Developmental Disorders'' is a peer-reviewed medical journal focusing on all aspects of autism spectrum disorders and related developmental disabilities. It was established in 1971 under the name ''Journal of Autism an ...
calling for more research into germline exposures as a potential cause of autism.


Advocacy

Before becoming a research advocate, Escher earned her J.D. degree and Master's in City and Regional Planning at UC Berkeley. In 1996, Jill Escher published her master's thesis, ''A Nightmare on Elm Street?: Government Liability for Innovative Street Design''. Concerned about sugar's effects on the public health, Escher founded ''Sugar Addiction Awareness Day'' in 2011, which promotes the claim that
sugar addiction A food or eating addiction is any behavioral addiction that is primarily characterized by the compulsive consumption of palatable (e.g., high fat and high sugar) food items which markedly activate the reward system in humans and other animal ...
among many people is a legitimate issue. She believes that some people are biologically susceptible to this addiction, and should eliminate sugar and flour from their diet. She has written articles on this topic, and has advocated for awareness in general. In 2002, Escher appealed to the
Blue Cross Blue Shield Blue Cross Blue Shield Association (BCBS, BCBSA) is a federation, or supraorganization, of, in 2022, 34 independent and locally operated BCBSA companies that provide health insurance in the United States to more than 106 million people. It was f ...
Federal Employee Program to provide reimbursement for speech-language services for all autistic individuals, claiming that speech therapy provides benefits to autistic individuals that are equivalent to medicine. Escher won her appeal but also asked the
Office of Personnel Management An office is a space where an organization's employees perform administrative work in order to support and realize objects and goals of the organization. The word "office" may also denote a position within an organization with specific duti ...
for a written decision indicating that BCBS was an error. This was cited as an example of a reimbursement appeal success. Escher founded the National Council on Severe Autism. Escher claims that the problem with the
neurodiversity Neurodiversity refers to diversity in the human brain and cognition, for instance in sociability, learning, attention, mood and other mental functions. It was coined in 1998 by sociologist Judy Singer, who helped popularize the concept alo ...
paradigm is that proponents of this view focus far too much on the positives of autism, and not on the difficulties. She claims that many ND advocates bully and terrorize people into silence. The
Autism Society of America The Autism Society of America (ASA) was founded in 1965 by Bernard Rimland and Ivar Lovaas together with Ruth C. Sullivan and a small group of other parents of children with autism. Its original name was the National Society for Autistic Childre ...
's national headquarters responded to two blog pieces written by Jill Escher. Escher wrote that she was worried that the government would prevent the creation of new residences and programs for autistic people, and the ASA said that they were optimistic that the government would do what is best. In response to a book review criticizing ''
Neurotribes ''NeuroTribes: The Legacy of Autism and the Future of Neurodiversity'' is a book by Steve Silberman that discusses autism and neurodiversity from historic, scientific, and advocacy-based perspectives. ''Neurotribes'' was awarded the Samuel Johnso ...
'' by
Steve Silberman Steve Silberman is an American writer for ''Wired (magazine), Wired'' magazine and has been an editor and contributor there for 14 years. In 2010, Silberman was awarded the American Association for the Advancement of Science, AAAS "Kavli Science ...
, where she claims that Silberman ignores the effects of severe autism, the ASA said that they respect the views of Silberman. Escher responded by claiming that the government needs a better plan for housing for autistic people, and that the ASA should explain why they support Steve Silberman's work.


Bibliography

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References


External links

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Germline Exposures
{{DEFAULTSORT:Escher, Jill 1965 births 21st-century American writers Living people American women lawyers American lawyers California lawyers Stanford University alumni UC Berkeley School of Law alumni 21st-century American women